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다양한 임상양상을 보이는 두경부의 이식 후 림프증식성 질환: 3예

Various Clinical Presentation of Post-Transplant Lymphoproliferative Disorder in Head and Neck: A Case Series of 3 Patients

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주제분류이비인후과학

초록

The outcome of solid organ and bone marrow transplantation has been dramatically improvedwith the development of immunosuppressive agent. However, the use of immunosuppressiveagents could increase the risk of malignancies such as post-transplant lymphoproliferative disorder(PTLD). PTLD is regarded as the lymphoid malignancy of patients using immunosuppressiveagents, and it could present diverse and non-specific symptoms. It involves variousorgans including the tonsil, adenoid, lymph node, and the brain. Because of its poor prognosis,an early suspicion of pathologic diagnosis is crucial for the treatment of PTLD. In this report,we demonstrate the case of three pediatric patients who had been treated for PTLD of variousclinical presentations by early suspicion and pathologic diagnosis.

Abstract

The outcome of solid organ and bone marrow transplantation has been dramatically improvedwith the development of immunosuppressive agent. However, the use of immunosuppressiveagents could increase the risk of malignancies such as post-transplant lymphoproliferative disorder(PTLD). PTLD is regarded as the lymphoid malignancy of patients using immunosuppressiveagents, and it could present diverse and non-specific symptoms. It involves variousorgans including the tonsil, adenoid, lymph node, and the brain. Because of its poor prognosis,an early suspicion of pathologic diagnosis is crucial for the treatment of PTLD. In this report,we demonstrate the case of three pediatric patients who had been treated for PTLD of variousclinical presentations by early suspicion and pathologic diagnosis.

참고문헌 (14)

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