Acoustic Change Complex에 기반한 와우소실영역 검사의 객관적인 방법 제시를 위한 예비 연구
The Objective Test of Cochlear Dead Region Using Acoustic Change Complex: A Preliminary Report
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Background and Objectives Cochlear dead region (CDR) is a region in the cochlear wherehearing loss has occurred due to damage to the inner hair cells and/or neurons. Recently, a subjectivetest involving a pure-tone test in the presence of threshold-equalizing noise (TEN) wasintroduced to identify CDR. However, for uncooperative patients, such a subjective methodwould be unsuitable and objective methods would be needed instead to detect CDR. The acousticchange complex (ACC) is an evoked potential elicited by changes in the ongoing sound. In thisstudy, we developed an objective method of identifying CDR by combining ACC response witha TEN test, namely the TEN-ACC test, and investigated its feasibility in normal-hearing listeners. Subjects and Method Ten normal-hearing subjects participated in this study. All subjectsunderwent both behavioral TEN test and electrophysiological TEN-ACC test. The stimuli forthe TEN-ACC test consisted of TEN and embedded pure tones with different frequencies/signalsto noise ratios (SNRs). To identify the thresholds, the range SNR of stimulation was variedfrom 0 to 20 dB, in stages of 4 dB. Results The ACC responses of all subjects who participated in this study were well elicited bystimuli developed for the TEN-ACC test. We confirm that the pure-tones embedded in TENelicited the objective ACC response. Conclusion The results of this study suggest that the novel TEN-ACC test can be applied toevoke ACC in normal-hearing listeners. Future research should incorporate hearing-impairedlisteners to determine the feasibility of the TEN-ACC test as an objective method to identifyCDR.
Abstract
Background and Objectives Cochlear dead region (CDR) is a region in the cochlear wherehearing loss has occurred due to damage to the inner hair cells and/or neurons. Recently, a subjectivetest involving a pure-tone test in the presence of threshold-equalizing noise (TEN) wasintroduced to identify CDR. However, for uncooperative patients, such a subjective methodwould be unsuitable and objective methods would be needed instead to detect CDR. The acousticchange complex (ACC) is an evoked potential elicited by changes in the ongoing sound. In thisstudy, we developed an objective method of identifying CDR by combining ACC response witha TEN test, namely the TEN-ACC test, and investigated its feasibility in normal-hearing listeners. Subjects and Method Ten normal-hearing subjects participated in this study. All subjectsunderwent both behavioral TEN test and electrophysiological TEN-ACC test. The stimuli forthe TEN-ACC test consisted of TEN and embedded pure tones with different frequencies/signalsto noise ratios (SNRs). To identify the thresholds, the range SNR of stimulation was variedfrom 0 to 20 dB, in stages of 4 dB. Results The ACC responses of all subjects who participated in this study were well elicited bystimuli developed for the TEN-ACC test. We confirm that the pure-tones embedded in TENelicited the objective ACC response. Conclusion The results of this study suggest that the novel TEN-ACC test can be applied toevoke ACC in normal-hearing listeners. Future research should incorporate hearing-impairedlisteners to determine the feasibility of the TEN-ACC test as an objective method to identifyCDR.
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