First Case of Skin and Soft Tissue Infection Caused by Mycoplasma hominis in a Pediatric Immunocompromised Patient
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Dear Editor, Mycoplasma hominis is a part of the urogenital commensal flora, with higher bacterial loads in women compared with men. Thus, infections of M. hominis are usually associated with endocervicitis and pelvic inflammatory diseases. Although rare, M. hominis can also cause various extra-urogenital infections, such as skin and soft tissue infections (SSTIs) [1, 2], central nervous system (CNS) infection, mediastinitis, and disseminated infection [3-6]. Because M. hominis lacks a cell wall and shows resistance to cell wall-acting antibiotics, including carbapenem and glycopeptides, it is important to accurately identify this bacterium and initiate appropriate treatment in the case of infection. Clindamycin shows the highest in vitro activity against M. hominis, followed by fluoroquinolones [4].
Abstract
Dear Editor, Mycoplasma hominis is a part of the urogenital commensal flora, with higher bacterial loads in women compared with men. Thus, infections of M. hominis are usually associated with endocervicitis and pelvic inflammatory diseases. Although rare, M. hominis can also cause various extra-urogenital infections, such as skin and soft tissue infections (SSTIs) [1, 2], central nervous system (CNS) infection, mediastinitis, and disseminated infection [3-6]. Because M. hominis lacks a cell wall and shows resistance to cell wall-acting antibiotics, including carbapenem and glycopeptides, it is important to accurately identify this bacterium and initiate appropriate treatment in the case of infection. Clindamycin shows the highest in vitro activity against M. hominis, followed by fluoroquinolones [4].
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