매실추출물의 항균특성
Antimicrobial Characteristic of Prunus mune extract
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참고문헌
초록
매실추출물의 항균력을 조사한 결과, 250 μg/mL 이상의 농도에서 뚜렷한 항균활성을 보였고, 광역의 병원성 및 부패성 미생물들에 대하여 항균활성을 나타내었다. 또한, 매실추출물의 항균물질은 넓은 범위의 온도(40～120℃) 및 pH(3～11)에서 안정성을 나타냈다. 따라서 매실추출물의 항균물질은 항균활성이 높고, 항균 spectrum이 광범위할 뿐아니라, 넓은 범위의 온도 및 pH에 안정하여 이상적인 천연 항균제로서의 개발가능성을 제시하였다. 아울러, 매실추출물의 항균작용을 조사한 결과, 매실추출물에는 두 종류 이상의 항균물질이 존재하며 이 물질들의 상승작용으로 항균활성을 나타냄을 확인하였다. 매실추출물의 항균활성은 친수성 성분임을 확인하였으며, 항균물질의 주요 작용기작은 세포막 perturbation에 기인한 것으로 사료되었다.
Abstract
Prunus mume extracts showed antimicrobial effects remarkably against the wide spectrum of putrefactive and food spoilage microorganisms above 250 ppm of concentration. Their thermal and pH stabilities were effective under the range of temperature (40℃120℃) and pH (311). Prunus mume extracts seemed to be a natural antimicrobial ideally with the view of their effectiveness and thermal & pH stabilities. In addition, their action modes suggested that their hydrophillic components would perturb the fucntions of microbial cell membranes synergistically.
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