인삼과 당근 즙액 첨가 참취녹즙이 흰쥐의 혈청지질에 미치는 영향
Effect of Aster scaber Juice supplemented with Carrot and Ginseng extracts on Serum Lipid in Rats
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초록
The effect on serum lipid of green aster juice blended with ginseng and carrot extracts was investigated using rats injected with CCl4. The rats were classified with four groups: (i) normal control (NC), (ii) rats fed with the blended juice (BA), (iii) rats treated with CCl4 after having been on a normal diet for 4 weeks (NC-CCl4), and (iv) rats treated with CCl4 after having been fed the blended juice for 4 weeks (BA-CCl4). All groups had similar feed intake. The weight gains and feed efficiency ratio were lower in the NC-CCl4 group. The liver weight per body weight was much higher in the NC-CCl4 group than the NC group, but did not differ between the BA-CCl4 and BA groups. Triglycerides increased only for the NC-CCl4 group (88.72 mg/dL); the other groups had similar levels (56.48-65.33 mg/dL). The BA group had the lowest total cholesterol level (74.08 mg/dL) the other groups had similar levels (96.78-108.83 mg/dL). HDL-cholesterol was lower in the NC-CCl4 group (40.56 mg/dL) compared with the NC group (48.95 mg/dL), but there was no difference between the BA and BA-CCl4 groups. The LDL-cholesterol level was higher in the NC-CCl4 group (55.20 mg/dL the highest level) than the NC group (43.33 mg/dL), and higher in the BA-CCl4 group (50.10 mg/dL) than the BA group (18.09 mg/dL). The lipid peroxide content was much higher in the NC-CCl4 group (22.61 nmol/g) than the NC group (12.52 nmol/g), but the BA-CCl4 (17.41 nmol/g) and BA (13.99 nmol/g) groups were similar. The glutathione content was much lower in the NC-CCl4 group (2.25 μmol/g) than the NC and BA groups, and decreased to 2.63 μmol/g for the BA-CCl4 group. The glutathione content of the BA-CCl4 recovered to the level of that in the NC group.
Abstract
The effect on serum lipid of green aster juice blended with ginseng and carrot extracts was investigated using rats injected with CCl4. The rats were classified with four groups: (i) normal control (NC), (ii) rats fed with the blended juice (BA), (iii) rats treated with CCl4 after having been on a normal diet for 4 weeks (NC-CCl4), and (iv) rats treated with CCl4 after having been fed the blended juice for 4 weeks (BA-CCl4). All groups had similar feed intake. The weight gains and feed efficiency ratio were lower in the NC-CCl4 group. The liver weight per body weight was much higher in the NC-CCl4 group than the NC group, but did not differ between the BA-CCl4 and BA groups. Triglycerides increased only for the NC-CCl4 group (88.72 mg/dL); the other groups had similar levels (56.48-65.33 mg/dL). The BA group had the lowest total cholesterol level (74.08 mg/dL) the other groups had similar levels (96.78-108.83 mg/dL). HDL-cholesterol was lower in the NC-CCl4 group (40.56 mg/dL) compared with the NC group (48.95 mg/dL), but there was no difference between the BA and BA-CCl4 groups. The LDL-cholesterol level was higher in the NC-CCl4 group (55.20 mg/dL the highest level) than the NC group (43.33 mg/dL), and higher in the BA-CCl4 group (50.10 mg/dL) than the BA group (18.09 mg/dL). The lipid peroxide content was much higher in the NC-CCl4 group (22.61 nmol/g) than the NC group (12.52 nmol/g), but the BA-CCl4 (17.41 nmol/g) and BA (13.99 nmol/g) groups were similar. The glutathione content was much lower in the NC-CCl4 group (2.25 μmol/g) than the NC and BA groups, and decreased to 2.63 μmol/g for the BA-CCl4 group. The glutathione content of the BA-CCl4 recovered to the level of that in the NC group.
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