본문 바로가기
KERD
논문KCI 등재

A Rare Human Case of Dirofilaria repens Infection in the Subcutaneous Posterior Thorax with Molecular Identification

1

조회

0

다운로드

0

인용

0

참고문헌

키워드

초록

The emergence of dirofilarial infections in Asia including Vietnam is a clinically significant threat to the community. We here report a rare case of subcutaneous Dirofilaria repens infection on the posterior thoracic wall in a young woman presenting a painful, itchy, and palpable nodule. The adult worm was identified by mitochondrial cox1 and nuclear ITS-2 sequence determination. The diagnosis was additionally confirmed by 16S rRNA sequencing of the endosymbiont Wolbachia pipientis commonly co-existing with D. repens. This is a rare case of subcutaneous human infection on the posterior thoracic region caused by D. repens.

Abstract

The emergence of dirofilarial infections in Asia including Vietnam is a clinically significant threat to the community. We here report a rare case of subcutaneous Dirofilaria repens infection on the posterior thoracic wall in a young woman presenting a painful, itchy, and palpable nodule. The adult worm was identified by mitochondrial cox1 and nuclear ITS-2 sequence determination. The diagnosis was additionally confirmed by 16S rRNA sequencing of the endosymbiont Wolbachia pipientis commonly co-existing with D. repens. This is a rare case of subcutaneous human infection on the posterior thoracic region caused by D. repens.

참고문헌 (22)

  1. Simón F, "Human and animal dirofilariasis: the emergence of a zoonotic mosaic", Clin Microbiol Rev, 25, pp.507~544 (2012)
  2. Casiraghi M, "Mapping the presence of Wolbachia pipientis on the phylogeny of filarial nematodes: evidence for symbiont loss during evolution", Int J Parasitol, 34, pp.191~203 (2004)
  3. Cancrini G, "Aedes albopictus and Culex pipiens implicated as natural vectors of Diroflaria repens in central Italy", J Med Entomol, 44, pp.1064~1066 (2007)
  4. Dang TC, "A human case of subcutaneous dirofilariasis caused by Dirofilaria repens in Vietnam: histologic and molecular confirmation", Parasitol Res, 107, pp.1003~1007 (2010)
  5. Nguyen Van De, "Dirofilaria repens in Vietnam: Detection of 10 Eye and Subcutaneous Tissue Infection Cases Identified by Morphology and Molecular Methods", The Korean Journal of Parasitology, 50(2), pp.137~141 (2012), 대한기생충학ㆍ열대의학회[DOI]
  6. Sathyan P, "Subcutaneus infection by Dirofilaria repens", Indian J Med Microbiol, 24, pp.61~62 (2006)
  7. Rishniw M, "Discrimination between six species of canine microfilariae by a single polymerase chain reaction", Vet Parasitol, 135, pp.303~314 (2006)
  8. Tamura K, "MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods", Mol Biol Evol, 28, pp.2731~2739 (2011)
  9. Khoramnia R, "Images in clinical medicine: subconjunctival Dirofilaria repens", N Engl J Med, 363, pp.e37~ (2010)
  10. Sviben M, "Dirofilaria repens as a cause of subconjunctival infection in a 77-years old female patient from Croatia-a case report", Coll Antropol, 37, pp.995~997 (2013)
  11. Foroulis CN, "Pulmonary dirofilariasis mimicking lung tumor with chest wall and mediastinal invasion", Thorac Cardiovasc Surg, 53, pp.173~175 (2005)
  12. Mulanovich EA, "A case of Dirofilaria pulmonary infection coexisting with lung cancer", J Infect, 56, pp.241~243 (2008)
  13. Pozgain Z, "Live Dirofilaria immitis found during coronary artery bypass grafting procedure", Eur J Cardiothorac Surg, 46, pp.134~136 (2014)
  14. Maltezos ES, "Human subcutaneous dirofilariasis: a report of three cases manifesting as breast or axillary nodules", Scott Med J, 47, pp.86~88 (2002)
  15. Pampiglione S, "Human dirofilariasis in Italy: a new case in the spermatic cord", Parasitologia, 44, pp.93~96 (2002)
  16. Genchi C, "Dirofilarial infection in Europe", Vector-borne Zoonot Dis, 11, pp.1307~1317 (2011)
  17. Leccia N, "Pseudo-tumor of the scrotum, a rare clinical presentation of dirofilariasis: a report of two autochthonous cases due to Dirofilaria repens", Pathog Glob Health, 106, pp.370~372 (2012)
  18. Hermosilla C, "First autochthonous case of canine ocular Dirofilaria repens infection in Germany", Vet Rec, 158, pp.134~135 (2006)
  19. Grandi G, "Mappe Parasitologiche, Vol. 8", pp.59~66 (2007), Universita degli Studi di Napoli Federico II
  20. Dantas-Torres F, "Dirofilariosis in the Americas: a more virulent Dirofilaria immitis?", Parasit Vectors, 6, pp.288~ (2013)
  21. Chan CC, "A rare case of Dirofilaria repens infection", J Laryngol Otol, 127, pp.607~609 (2013)
  22. Dissanaike AS, "Filaria in the vitreous of the eye of man in peninsular Malaysia", Am J Trop Med Hyg, 26, pp.1143~1147 (1977)

관련 논문AI추천

이 간행물의 다른 논문 (16건)