Validity and Reliability of the Greek Version of the Multiple Sclerosis International Quality-of-Life Questionnaire
1
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Background and Purpose There are no data regarding psychometrically validated, healthrelated quality-of-life instruments designed specifically for patients with multiple sclerosis (MS) in Greece. Recently, the MS International Quality-of-Life questionnaire (MusiQoL), a multidimensional, self-administered questionnaire, which is available in 14 languages (including Greek), has been validated using a large international sample. We investigated the validity and reliability of the Greek version of the MusiQoL. Methods Consecutive patients with different types and severities of MS were recruited from two tertiary-care centers in Greece. All patients completed the MusiQoL, the Short-Form-36 quality-of-life questionnaire (SF-36), and a symptom checklist at baseline and 21±7 days (mean± SD) later. Data regarding sociodemographic status, MS history, and functional outcome were also collected prospectively. Construct validity, internal consistency, reproducibility, and external consistency were tested. Results A total of 92 patients was evaluated. The construct validity was confirmed in terms of satisfactory item-internal consistency correlations and scaling success (87.5-100%) of itemdiscriminant validity. The dimensions of the MusiQoL exhibited high internal consistency (Cronbach’s alpha: 0.63-0.96), and reproducibility was satisfactory (intraclass correlation coefficients: 0.69-0.99). External validity testing indicated that the MusiQoL correlated significantly with all SF-36 dimension scores (Spearman’s correlation: 0.43-0.76). Conclusions The Greek version of the MusiQoL appears to be a valid and reliable instrument for measuring quality of life in Greek MS patients.
Abstract
Background and Purpose There are no data regarding psychometrically validated, healthrelated quality-of-life instruments designed specifically for patients with multiple sclerosis (MS) in Greece. Recently, the MS International Quality-of-Life questionnaire (MusiQoL), a multidimensional, self-administered questionnaire, which is available in 14 languages (including Greek), has been validated using a large international sample. We investigated the validity and reliability of the Greek version of the MusiQoL. Methods Consecutive patients with different types and severities of MS were recruited from two tertiary-care centers in Greece. All patients completed the MusiQoL, the Short-Form-36 quality-of-life questionnaire (SF-36), and a symptom checklist at baseline and 21±7 days (mean± SD) later. Data regarding sociodemographic status, MS history, and functional outcome were also collected prospectively. Construct validity, internal consistency, reproducibility, and external consistency were tested. Results A total of 92 patients was evaluated. The construct validity was confirmed in terms of satisfactory item-internal consistency correlations and scaling success (87.5-100%) of itemdiscriminant validity. The dimensions of the MusiQoL exhibited high internal consistency (Cronbach’s alpha: 0.63-0.96), and reproducibility was satisfactory (intraclass correlation coefficients: 0.69-0.99). External validity testing indicated that the MusiQoL correlated significantly with all SF-36 dimension scores (Spearman’s correlation: 0.43-0.76). Conclusions The Greek version of the MusiQoL appears to be a valid and reliable instrument for measuring quality of life in Greek MS patients.
참고문헌 (24)
- McCrone P, "Multiple sclerosis in the UK: service use, costs, quality of life and disability", Pharmacoeconomics, 26, pp.847~860 (2008)
- Miller DM, "Health-related quality of life assessment in multiple sclerosis", Rev Neurol Dis, 5, pp.56~64 (2008)
- Motl RW, "Physical activity, self-efficacy, and quality of life in multiple sclerosis", Ann Behav Med, 35, pp.111~115 (2008)
- Whalley D, "Measuring quality of life in patients with depression or anxiety", Pharmacoeconomics, 8, pp.305~315 (1995)
- Solari A, "Role of health-related quality of life measures in the routine care of people with multiple sclerosis", Health Qual Life Outcomes, 3, pp.16~ (2005)
- Simeoni M, "Validation of the Multiple Sclerosis International Quality of Life questionnaire", Mult Scler, 14, pp.219~230 (2008)
- Poser CM, "New diagnostic criteria for multiple sclerosis: guidelines for research protocols", Ann Neurol, 13, pp.227~231 (1983)
- McDonald WI, "Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis", Ann Neurol, 50, pp.121~127 (2001)
- Ware JE Jr, "The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection", Med Care, 30, pp.473~483 (1992)
- Tsivgoulis G, "Associations of the Expanded Disability Status Scale with anxiety and depression in multiple sclerosis outpatients", Acta Neurol Scand, 115, pp.67~72 (2007)
- Rentzos M, "IL-15 is elevated in serum and cerebrospinal fluid of patients with multiple sclerosis", J Neurol Sci, 241, pp.25~29 (2006)
- Kurtzke JF, "Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS)", Neurology, 33, pp.1444~1452 (1983)
- Kurtzke JF, "On the evaluation of disability in multiple sclerosis", Neurology, 11, pp.686~694 (1961)
- Hauser SL, "Intensive immunosuppression in progressive multiple sclerosis. A randomized, three-arm study of high-dose intravenous cyclophosphamide, plasma exchange, and ACTH", N Engl J Med, 308, pp.173~180 (1983)
- Folstein MF, "The Mini-Mental State Examination", Arch Gen Psychiatry, 40, pp.812~ (1983)
- Guy W, "ECDEU Assessment manual for psychopharmacology, revised", pp.218~222 (1976), U.S. Department of Health and Human Services
- Piperidou H, "The Greek version of the Quality of Life in Epilepsy Inventory (QOLIE-31)", Qual Life Res, 15, pp.833~839 (2006)
- Piperidou C, "Association of demographic, clinical and treatment variables with quality of life of patients with epilepsy in Greece", Qual Life Res, 17, pp.987~996 (2008)
- Courts NF, "Focus groups: the lived experience of participants with multiple sclerosis", J Neurosci Nurs, 36, pp.42~47 (2004)
- Somerset M, "Factors that contribute to quality of life outcomes prioritised by people with multiple sclerosis", Qual Life Res, 12, pp.21~29 (2003)
- Kaul P, "Influence of racial disparities in procedure use on functional status outcomes among patients with coronary artery disease", Circulation, 111, pp.1284~1290 (2005)
- Chavers LS, "Racial and socioeconomic disparities in oral disadvantage, a measure of oral health-related quality of life: 24-month incidence", J Public Health Dent, 62, pp.140~147 (2002)
- Cella DF, "Validation of the functional assessment of multiple sclerosis quality of life instrument", Neurology, 47, pp.129~139 (1996)
- Vickrey BG, "A healthrelated quality of life measure for multiple sclerosis", Qual Life Res, 4, pp.187~206 (1995)