In Vitro Effect of Methanolic Extract of Argemone mexicana against Trichomonas vaginalis
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Infections caused by Trichomonas vaginalis in humans are one of the main public health problems caused by sexually transmitted diseases. Objective of this study was to evaluate potential biological activity of the medicinal plant Argemone mexicana (Mexican poppy) on T. vaginalis. Methanolic extracts of the stems and leaves of A. mexicana, and different fractions were prepared with solvents of different polarities. The extracts and functional groups were detected containing sterols, triterpenes, quinones, flavonoids and, alkaloids. Extracts from both the stems and leaves of A. mexicana inhibited the growth of T. vaginalis with half-maximal inhibitory concentration value of 70.6 and 67.2 μg/ml, respectively. In the active fractions, the most abundant compounds were berberine and jatrorrhizine, with presumed antiparasitic activity.
Abstract
Infections caused by Trichomonas vaginalis in humans are one of the main public health problems caused by sexually transmitted diseases. Objective of this study was to evaluate potential biological activity of the medicinal plant Argemone mexicana (Mexican poppy) on T. vaginalis. Methanolic extracts of the stems and leaves of A. mexicana, and different fractions were prepared with solvents of different polarities. The extracts and functional groups were detected containing sterols, triterpenes, quinones, flavonoids and, alkaloids. Extracts from both the stems and leaves of A. mexicana inhibited the growth of T. vaginalis with half-maximal inhibitory concentration value of 70.6 and 67.2 μg/ml, respectively. In the active fractions, the most abundant compounds were berberine and jatrorrhizine, with presumed antiparasitic activity.
참고문헌 (37)
- Kissinger P, "Trichomonas vaginalis : a review of epidemiologic, clinical and treatment issues", BMC Infect Dis, 15, pp.307~ (2015)
- Wendel KA, "Trichomoniasis : challenges to Appropriate Management", Clin Infect Dis, 44(suppl), pp.123~129 (2007)
- Mokdad AH, "Health in times of uncertainty in the eastern Mediterranean region, 1990-2013 : a systematic analysis for the Global Burden of Disease Study 2013", Lancet Glob Heal, 4, pp.e704~ (2016)
- Patel B, "Effect of different extracts from Celosia argentea on calcium and phosphate inhibition in vitro", Int J Pharm Pharm Sci, 3, pp.337~339 (2011)
- Sharanappa R, "Plant profile, phytochemistry and pharmacology of Argemone Mexicana Linn. A review", Int J Pharm Pharm Sci, 6, pp.45~53 (2014)
- Sharma A, "Antibacterial activities of medicinal plants used in Mexican traditional medicine", J Ethnopharmacol, 208, pp.264~329 (2017)
- Bhalke RD, "Anti-stress and antiallergic effect of Argemone mexicana stems in Asthma", Arch Pharm Sci Res, 1, pp.127~129 (2009)
- Chang YC, "Cytotoxic benzophenanthridine and benzylisoquinoline alkaloids from Argemone mexicana", Z Naturforsch C J Biosci, 58, pp.521~526 (2003)
- Magos-guerrero GA, "Exploratory studies of some Mexican medicinal plants : cardiovascular effects in rats with and without hypertension", J Intercult Ethnopharmacol, 3, pp.274~279 (2013)
- Sharma BD, "Epidemic dropsy in India", Postgrad Med J, 75, pp.657~661 (1999)
- Rubio-Pina J, "Pharmaceutical applications of the benzylisoquinoline alkaloids from Argemone mexicana L", Curr Top Med Chem, 13, pp.2200~2207 (2013)
- Willcox ML, "Argemone mexicana decoction for the treatment of uncomplicated falciparum malaria", Trans R Soc Trop Med Hyg, 101, pp.1190~1198 (2007)
- Brahmachari G, "Argemone mexicana : chemical and pharmacological aspects", Rev bras farmacogn, 23, pp.559~575 (2013)
- Malebo HM, "Anti-protozoal activity of aporphine and protoberberine alkaloids from Annickia kummeriae (Engl. & Diels) Setten & Maas (Annonaceae)", BMC Complement Altern Med, 13, pp.48~ (2013)
- Harborne JB, "Phytochemical Methods. A Guide to Modern Techniques of Plant analysis", pp.54~84 (1998), Chapman and Hall
- Mata-Cárdenas BD, "A new vial microassay to screen antiprotozoal drugs", Pharmacologyonline, 1, pp.529~537 (2008)
- Ntie-Kang F, "The potential of anti-malarial compounds derived from African medicinal plants, part II : a pharmacological evaluation of non-alkaloids and non-terpenoids", Malar J, 13, pp.81~ (2014)
- Kumar G, "Hemolytic activity of Indian medicinal plants towards human erythrocytes : an in vitro study", Elixir Appl Botany, 40, pp.5534~5537 (2011)
- Lakshmi G, "Phytochemical profile, in vitro antioxidant and hemolytic activities of various leaf extract of Nymphaea Nouchali Linn : an in vitro study", Int J Pharm Pharm Sci, 6, pp.548~552 (2014)
- Singh S, "A new benzylisoquinoline alkaloid from Argemone mexicana", Nat Prod Res, 24, pp.63~67 (2010)
- Trujillo-Villanueva K, "The sequential exposure to jasmonate, salicylic acid and yeast extract promotes sanguinarine accumulation in Argemone mexicana cell cultures", Biotechnol Lett, 34, pp.379~385 (2012)
- Singh S, "Cytotoxicity of alkaloids isolated from Argemone mexicana on SW480 human colon cancer cell line", Pharm Biol, 54, pp.740~745 (2016)
- Kostara I, "Growth and survival of Trichomonas vaginalis", J Med Microbiol, 47, pp.555~560 (1998)
- Schrader FC, "The antimalarial pipeline-an update", Int J Med Microbiol, 302, pp.165~171 (2012)
- Elizondo-Luévano JH, "In vitro study of antiamoebic activity of methanol extracts of Argemone mexicana on trophozoites of Entamoeba histolytica HM1-IMSS", Can J Infect Dis Med Microbiol, 2018, pp.7453787~ (2018)
- Raghav D, "Berberine induces toxicity in HeLa cells through perturbation of microtubule polymerization by binding to tubulin at a unique site", Biochemistry, 56, pp.2594~2611 (2017)
- Simoes-pires C, "Reverse pharmacology for developing an anti-malarial phytomedicine. The example of Argemone mexicana", Int J Parasitol Drugs Drug Resist, 4, pp.338~346 (2014)
- Grycová L, "Quaternary protoberberine alkaloids", Phytochemistry, 68, pp.150~175 (2007)
- Liu F, "Determination of berberine, palmatine and jatrorrhizine in rabbit plasma by liquid chromatography-electrospray ionization-mass spectrometry", J Pharm Biomed Anal, 56, pp.1006~1015 (2011)
- Tang DQ, "Quantitative and qualitative analysis of common peaks in chemical fingerprint of Yuanhu Zhitong tablet by HPLC-DAD-MS", MS, 2014, pp.4, 96~106
- Birdsall TC, "Therapeutic potential of an alkaloid found in several medicinal plants", Altern Med Rev, 2, pp.94~103 (1997)
- Kaneda Y, "In vitro effects of berberine sulphate on the growth and structure of Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis", Ann Trop Med Parasitol, 85, pp.417~425 (1991)
- Li Y, "Metabolic profiling analysis of berberine, palmatine, jatrorrhizine, coptisine and epiberberine in zebrafish by ultra-high performance liquid chromatography coupled with LTQ Orbitrap mass spectrometer", Xenobiotica, 45, pp.302~311 (2015)
- Vinjamuri S, "In vitro evaluation of hemolytic activity and cell viability assay of hexanoic extracts of Bridelia ferruginea Benth", World J Pharm Pharm Sci, 4, pp.1263~1268 (2015)
- Karimi G, "Protective effects of aqueous and ethanolic extracts of Nigella sativa L. and Portulaca oleracea L. on free radical induced hemolysis of RBCs", Daru, 19, pp.295~300 (2011)
- 김정현, "Interaction between Trichomonas vaginalis and the Prostate Epithelium", Parasites, Hosts and Diseases, 55(2), pp.213~218 (2017), 대한기생충학ㆍ열대의학회[DOI]
- Ávila-Blanco ME, "Amoebicidal activity of essential oil of Dysphania ambrosioides (L.) Mosyakin & Clemants in an amoebic liver abscess hamster model", Evid Based Complement Alternat Med, 2014, pp.1~7 (2014)
