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Pathogenic free-living amoebae in Korea (Mini-Review)

임경일|신호준
대한기생충학ㆍ열대의학회 (The Korean Society For Parasitology and Tropical Medicine)|2004.09|Parasites, Hosts and Diseases|제42권 제3호|pp. 93-119

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참고문헌

주제분류예방의학/직업환경의학

초록

Abstract

Acanthamoeba and Naegleria are widely distributed in fresh water, soil and dust throughout the world, and cause meningoencephalitis or keratoconjunctivitis in humans and other mammals. Korean isolates, namely, Naegleria sp. YM-1 and Acanthamoeba sp. YM-2, YM-3, YM-4, YM-5, YM-6 and YM-7, were collected from sewage, water puddles, a storage reservoir, the gills of a fresh water fish, and by corneal washing. These isolates were categorized into three groups based on the mortalities of infected mice namely, highly virulent (YM-4), moderately virulent (YM-2, YM-5 and YM-7) and nonpathogenic (YM-3). In addition, a new species of Acanthamoeba was isolated from a freshwater fish in Korea and tentatively named Korean isolate YM-4. The morphologic characters of its cysts were similar to those of A. culbertsoni and A. royreba, which were previously designated as Acanthamoeba group III. Based on experimentally infected mouse mortality, Acanthamoeba YM-4 was highly virulent. The isoenzymes profile of Acanthamoeba YM-4 was similar to that of A. royreba. Moreover, an anti-Acanthamoeba YM-4 monoclonal antibody reacted only with Acanthamoeba YM-4, and not with A. culbertsoni. Random amplified polymorphic DNA marker analysis and RFLP analysis of mitochondrial DNA and of a 18S small subunit ribosomal RNA, placed Acanthamoeba YM-4 in a separate cluster based on phylogenic distances. Thus Acanthamoeba YM-4 was identified as a new species, and assigned Acanthamoeba sohi. Up to the year 2002 in Korea, two clinical cases were found to be infected with Acanthamoeba spp. These patients died of meningoencephalitis. In addition, one case of Acanthamoeba pneumonia with an immunodeficient status was reported and Acanthamoeba was detected in several cases of chronic relapsing corneal ulcer, chronic conjunctivitis, and keratitis.

참고문헌 (144)

  1. "Fate of free-living amoebas inthe outer environment and in experimental host. YonseiJ Med Sci 12", pp.28~37 (1979)
  2. "Experimental meningoencephalitisby Naegleria fowleri in mice. Korean J Parasitol 22", pp.253~258 (1984)
  3. "Experimental studyon vertical transmission of immunity against Naegleriafowleri. Yonsei J Med Sci 19", pp.102~110 (1986)
  4. "Theprimary structure of the basic isoform of Acanthamoebaprofilin. Eur J Biochem 170", pp.597~601 (1988)
  5. "The amino acid sequence of Acanthamoebaprofilin. J Biol Chem 260", pp.834~840 (1985)
  6. "Production of respirable vesicles containing liveLegionella pneumophila cells by two Acanthamoeba spp.Appl Environ Microbiol 64", 64, pp.279~286 (1998)
  7. "Interstrain mitochondrial DNA polymorphismdetected in Acanthamoeba by re-striction endonucleaseanalysis. Mol Biochem Parasitol 8", pp.145~63 (1983)
  8. "Genotyping of Balamuthia mandrillaris basedon nuclear 18S and mitochondrial 16S rRNA genes. AmJ Trop Med Hyg 68", 68, pp.65~69 (2003)
  9. "Studies concerning the effects of nutritionon morphology of amoebas. II. Acanthamoeba castellanii", pp.73~181 (1963)
  10. "1861. In An illustratedguide to the protozoa Society of Protozoologists", pp.~211 (1985)
  11. "Genes of Acanthamoeba", pp.17~25 (1990)
  12. "Patterns of “lipovirus” antibodyin human populations. J Immunol 92", pp.313~319 (1964)
  13. "Purification of cysteineproteinases from adult Schistosoma mansoni. ArchBiochem Biophys 256", pp.560~568 (1987)
  14. "Biochemical and molecular characterization of a strainKA", S2 of Acanthamoeba castellanii isolated from Koreansoil. Korean J Parasitol 34, 1996, 79~85
  15. "Case report and characterizationof the isolates. Program and Abstracts of the38th Annual Meeting of The Korean Society forParasitology. Korea. p35." (1996)
  16. "Study on the determinationof free-living amoebae pathogenicity by ultrastructuralcytochemical method. Yonsei J Med Sci 13", pp.72~81 (1980)
  17. "Growth ofLegionella pneumophila in Acanthamoeba castellaniienhances invasion. Infect Immun 62", pp.3254~3261 (1994)
  18. "Legionella pneumophilia entry gene rtxA isinvolvd in virulence.", 69, pp.508~517 (2001)
  19. "Evaluationof evolutionary divergence in the genus Naegleria byanalysis of ribosomal DNA plasmid restriction patterns.Mol Biochem Parasitol 34", pp.281~296 (1989)
  20. "Observations on animal pathogenicity. Science 127", pp.1506~ (1958)
  21. "Relationshipamong 31 strains of Acanthamoeba based upon nonmorphologicalcharacters. J Protozool 28" (1981)
  22. "Amolecular approach to the phylogeny of Acanthamoeba.Biosystems 18", pp.399~405 (1985)
  23. "De Jonckheere J. 1977. Use of an axenic medium for differentiationbetween pathogenic and nonpathogenic Naegleriafowleri isolates. Appl Env Microbiol 33", pp.751~757
  24. "Differences in virulence of Naegleriafowleri. Pathol Biol 8", pp.453~458 (1979)
  25. "Isoenzyme and total protein analysisby agarose isoelectric focusing and taxonomy of thegenus Acanthamoeba. J Protozool 30", pp.701~706 (1983)
  26. "Taxonomy. In Amphizoic amoebaehuman pathology", pp.~48 (1987)
  27. "Amebic meningoencephalitiscaused by Balamuthia mandrillaris", 25, pp.1354~1358 (1997)
  28. "A retrospective study in Richmond", pp.737~742 (1970)
  29. "Infection of Acanthamoeba castellanii by Chlamydia pneumoniae.Appl Environ Microbiol 63", 63, pp.1396~1399 (1997), Heinemann M
  30. "Acute pyogenic meningoencephalitisprobably due to Acanthamoeba sp.", pp.740~742 (1965)
  31. "Amebo-flagellates as research partners Thelaboratory biology of Naegleria and Tetramitus. MethodsCell Physiol 4", pp.341~476 (1970)
  32. "Environmental sampling for pathogenicNaegleria. J Protozool 20", pp.497~498 (1973)
  33. "The useof physiological characterizations in the classification offive species of Acanthamoeba. J Gen Microbiol 107", pp.211~215 (1978)
  34. "Proteolytic enzymes of pathogenicand non-pathogenic strains of Acanthamoeba spp. TropMed Parasitol 44"
  35. "Complete nucleotide sequence and deduced polypeptidesequence of a nonmuscle myosin heavy chain genefrom Acanthamoeba evidence of a hinge in the rodliketail. J Cell Biol 105", pp.913~925 (1987)
  36. "Study on isoenzyme patternsof free-living amoebae", pp.15 75~86 (1982)
  37. "Isolation andcharacterization of a cDNA encoding a mammaliancathepsin L-like cysteine proteinase from Acanthamoebahealyi. Korean J Parasitol 40", pp.17~24 (2002)
  38. "Isolation and characterization of a cDNA encoding asubtilisin-like serine proteinases", pp.441~446 (2000)
  39. "a free-living amoeba recentlydemonstrated to cause granulomatous amebicencephalitis. J Infect Dis 179", pp.1305~1308 (1999)
  40. "Experimentalstudy on the pathogenicity of free-living amoebae.Yonsei J Med Sci 9"
  41. "Natural killer cell activityin mice infected with Acanthamoeba culbertsoni. Korean JParasitol 30", pp.101~112 (1992)
  42. "Pathogenic free-living amoebae in Korea", pp.7~8 (1996)
  43. "Acanthamoebiasis in Korea two newcases with clinical cases review.", 39, pp.478~484 (1998)
  44. "Observation onultrastructure and enzyme activity of free-living amoebae.Yonsei Rep Trop Med 7", pp.40~50 (1976)
  45. "Failure of immunization with Naegleriafowleri in mice born to immune mothers. Korean JParasitol 23", pp.151~155 (1985)
  46. "Hybridoma secretingmonoclonal antibody for free-living amoeba. JKorean Med Assoc 26", pp.157~162 (1983)
  47. "Immunological tests by anti-free-livingamoebas serum produced in experimental animals. I.Immobilization of free-living amoebas in vitro by rabbitantiserum. Korean J Parasitol 16", pp.41~46 (1978)
  48. "Passive immunity by splenocyte transferagainst amebic meningoencephalitis in mice. Korean JParasitol 26", pp.169~173 (1988)
  49. "Immunodepression duringexperimental Naegleria meningoencephalitis in mice.Korean J Parasitol 25"
  50. "a pathogenicKorean isolate YM-4 from a freshwater fish. Korean JParasitol 41", (sp.)
  51. "a new species isolated inKorea with genomic DNA study. Program andAbstracts of the 36th annual meeting of The KoreanSociety for Parasitology. Korea. p18." (1994)
  52. "Pathogenicity of Korean isolates of Acanthamoeba byobserving the experimental infection and zymodemes offive isoenzymes.", 37, pp.85~92 (1999)
  53. "Immunological tests by anti-free-livingamoebas serum produced in experimental animals. II.Indirect fluorescent antibody titers of anti-free-livingamoebas serum produced in rabbits. Korean J Parasitol16", pp.134~139 (1978)
  54. "Control of actin synthesis during the developmentof Acanthamoeba castellanii. Devel Biol 82", pp.113~126 (1981)
  55. "Enhancement of virulence ofNaegleria fowleri by growth in Vero-cell cultures. JParasitol 80", pp.149~151 (1994)
  56. "Concanavalin Ainducedagglutination of Naegleria. Am J Trop Med Hyg26", pp.856~858 (1977)
  57. "In vivo transfection system of the nfa1 genecloned from pathogenic Naegleria fowleri. DoctoralThesis for Ajou University School of Medicine" (2004)
  58. "Study on the agglutinabilityof free-living amoebae with phytoagglutininin consideration with their pathogenicity. Yonsei J MedSci 12", pp.34~44 (1979)
  59. "The role ofthymus in protective immunity to Naegleria fowleri.Yonsei J Med Sci 19", pp.1~12 (1986)
  60. "Acanthamoeba keratitisin contact lens wearer.", 36, pp.2042~2047 (1995)
  61. "Natural killer cell activity inmice infected with free-living amoeba with reference totheir pathogenicity. Korean J Parasitol 31", pp.239~248 (1993)
  62. "Cell-mediated immunity inmice infected with Acanthamoeba culbertsoni. Korean JParasitol 28", pp.143~154 (1990)
  63. "Effect of prednisolonetreatment on the experimental inducement ofprimary amoebic meningoencephalitis. Korean J Parasitol23", pp.165~172 (1985)
  64. "Acanthamoeba sinusitis with subsequent disseminationin an AIDS patient.", 79, pp.171~174 (2000)
  65. "A biochemical study on thecytolytic substance of Acanthamoeba culbertsoni. YonseiRep Trop Med 20", pp.32~35 (1989)
  66. "Correlation of isoenzymepatterns and the pathogenicity of free-livingamoebae collected in Korea. Yonsei J Med Sci 17", pp.320~340 (1984)
  67. "Analysis of blastogenesis oflymphocytes and their subpopulations in mice infectedwith Naegleria fowleri. Yonsei Rep Trop Med 24", pp.1~12 (1993)
  68. "A comparativestudy on hydrolase activities in Acanthamoeba culbertsoniand A. royreba. Korean J Parasitol 26", pp.95~106 (1988)
  69. "PCR and RFLP variation of conservedregion of small subunit ribosomal DNA amongAcanthamoeba isolates assigned to either A. castellanii orA. polyphaga.", 34, pp.127~134 (1996)
  70. "Ultrastructural changes ofAcanthamoeba cyst of clinical isolates after treatmentwith minimal cysticidal concentration of polyhexamethylenebiguanide.", 36, pp.7~13 (1998)
  71. "A riboprinting scheme for identificationof unknown Acanthamoeba isolates at specieslevel.", 40, pp.25~31 (2002)
  72. "Purification and characterizationof a secretory serine proteinase ofAcanthamoeba healyi isolated from GAE.", 86, pp.12~17 (2000)
  73. "Interstrain polymorphismsof isoenzyme profiles and mitochondrial DNAfingerprints among seven strains assigned toAcanthamoeba polyphaga.", 33, pp.331~340 (1995)
  74. "The effect of activeimmunization with Acanthamoeba culbertsoni in miceborn to immune mother. Korean J Parasitol 31", pp.157~163 (1993)
  75. "Non-radioactive DNAprobe and polymerase chain reaction procedures for thespecific detection of Acanthamoeba. Mol Cell Probes 8", pp.81~89 (1994)
  76. "Changes in the pathogenicityof Naegleria fowleri by serial brain passage in mice.Korean J Parasitol 21", pp.153~158 (1983)
  77. "The effect of silica onthe development of experimental Acanthamoeba meningoencephalitiswith reference to the macrophage role inmice. Korean J Parasitol 32", pp.259~266 (1994)
  78. "Protective immunity againstNaegleria meningoencephalitis in mice. Korean J Parasitol23", pp.293~299 (1985)
  79. "Study on the cell-mediatedimmunity in experimental Naegleria spp. infections.Korean J Parasitol 27", pp.177~186 (1989)
  80. "Contamination ofAcanthamoeba in contact lens care system.", 38, pp.756~761 (1997)
  81. "Anexperimental study on the cytotoxicity of free-livingamoebae. Yonsei J Med Sci 19", pp.358~370 (1986)
  82. "Purificationand characterization of a third isoform of myosin I fromAcanthamoeba castellanii. J Biol Chem 264", pp.19333~19339 (1989)
  83. "Interleukin-2 production andalteration of T cell subsets in mice infected withNaegleria fowleri. Korean J Parasitol 31", pp.249~257 (1993)
  84. "Granulomatous amebic encephalitis presenting as acerebral mass lesion. Acta Neuropathol 51", pp.85~91 (1980)
  85. "Free-living, amphizoic,and opportunistic amebas", 7, pp.583~598 (1997)
  86. "Free-livingamebic infections. In Pathology of infectious diseases", ii, pp.~1176 (1997)
  87. "Coexistent Acanthamoeba keratitis herpetickeratitis.", 115, pp.714~718 (1997)
  88. "Newapproaches to isolation in Medicinal Chemistry for the 21stCentury. Wermuth", pp.~118 (1992), expression and molecular modelingof proteases
  89. "Legionella-like slender rods multiplying within a strainof Acanthamoeba sp. isolated from drinking water.Parasitol Res 84", pp.304 84~88
  90. "Effects of zinc deficiencyon immune response in mouse. Korean J Nutr 21", pp.113~121 (1988)
  91. "Degradation ofimmunoglobulins protease inhibitors and interleukin-1by a secretory proteinase of Acanthamoeba castellanii.", 40, pp.93~99 (2002)
  92. "Actin genes and actin messengerRNA in Acanthamoeba castellanii. J Mol Biol 159", pp.1~18 (1982)
  93. "Multiplication of different Legionella species inMono Mac 6 cells and in Acanthamoeba castellanii.", 63, pp.1219~1224 (1997)
  94. "The pathogenesis of Acanthamoeba keratitis.", 1, pp.437~443 (1999)
  95. "Taxonomic criteria for limax amoebae withdescriptions of 3 new species of Hartmannella and 3 ofVahlkampfia. J Protozool 14", pp.499~521 (1967)
  96. "Re-definition of the genus Acanthamoebawith descriptions of three species. J Protozool 14", pp.709~724 (1967)
  97. "“An Illustrated Key to Freshwater and SoilAmoebae”. Freshwater Biological Association" (1976)
  98. "A new key to fresh water and soil gymnamoebae", pp.~122 (1988)
  99. "Cytotoxicity of a cysteine proteinase of adult Clonorchissinensis.", 33, pp.211~218 (1995)
  100. "Proteinase activity ofNaegleria spp. with special reference to their pathogenicity.Yonsei Rep Trop Med 24", pp.13~29 (1993)
  101. "Blastogenic responses ofsplenic lymphocytes to Naegleria fowleri lysates and Tcellmitogen in mice with primary amoebic meningoencephalitis.Korean J Parasitol 25", pp.1~6 (1987)
  102. "Changes in profiles ofmajor proteins in encysting Acanthamoeba castellanii.", 6, pp.341~347 (2002)
  103. "Identification of differentially expressedmouse mRNA induced by the infection of Acanthamoebaculbertsoni via DDRT-PCR analysis." (1996)
  104. "Comparative protein patterns of three thermophilicnon-pathogenic Naegleria isolates and two Naegleria fowleristrains by isoelectric focusing. Int J Parasitol 13", pp.113~118 (1983)
  105. "Thethree cortical membranes of the gregarines . III. Comparative studies of the membraneproteins among different sporozoan species during theirvegetative phase. J Protozool 29", pp.424~430 (1982)
  106. "Acting and actin-binding proteins.A critical evaluation of mechanisms and functions.Ann Rev Biochem 55", pp.987~1035 (1986)
  107. "Isolation and characterization of a cysteine proteinasefrom Fasciola hepatica adult worms. Mol Biochem Parasitol35", pp.89~96 (1989)
  108. "Proteinase activity of Acanthamoeba culbertsoniwith reference to pathogenicity." (1997)
  109. "Probable Acanthamoeba meningoencephalitis in a Koreanchild. Am J Clin Pathol 66", pp.723~730 (1976)
  110. "Acanthamoeba:a rare primaycause of rhinosinusitis.", 112, pp.1201~1203 (2002)
  111. "Ultrastructural observation ofNaegleria fowleri trophozoite in mouse brain and axenicculture. Korean J Parasitol 22", pp.259~266 (1984)
  112. "Taxonomic characteristics of mitotic nuclei", pp.18 382~388 (1971)
  113. "Pathogenicamoebas from brackish and ocean sediments with adescription of Acanthamoeba hatchetti. n. sp. Science 196", pp.1324~1325 (1977)
  114. "Efficacy of novel antimicrobialsagainst clinical isolates of opportunistic amebas.", 45, pp.612~618 (1998)
  115. "Comparative biology ofBalamuthia mandrillaris isolates.", pp.84~ (2001)
  116. "Amebic osteomyelitis in achild with acquired immunodeficiency syndrome", 18, pp.89~95 (1998)
  117. "Biochemical studies on proteinasein Acanthamoeba culbertsoni. Yonsei Rep Trop Med22", pp.21~28 (1991)
  118. "The maintenance of free-livingamoebae by cryopreservation. Korean J Parasitol 30", pp.151~153 (1992)
  119. "Cytopathic changes in rat microglial cells induced by pathogenic Acanthamoeba culbertsoni: Morphology and cytokine release", 8, pp.837~840 (2001)
  120. "Molecular cloningand characterization of a gene encoding a 13.1 kDa antigenicprotein of Naegleria fowleri.", 48, pp.713~717 (2001)
  121. "Isoenzyme patternsand phylogenetic relationships in Acanthamoeba spp. isolatedfrom contact lens containers in Korea.", 37, pp.229~236 (1999)
  122. "In vitro cytotoxicityof Acanthamoeba spp. isolated from contact lens containerin Korea by crystal violet staining and LDH releaseassay.", 38, pp.1~10 (2000)
  123. "Apoptosis of primary-culture rat microglia cells induced by pathogenicAcanthamoeba spp.", 7, pp.510~514 (2000)
  124. "Analysis of antigenic specificities ofNaegleria fowleri using EITB. Yonsei Rep Trop Med 23", pp.9~13 (1992)
  125. "Effect of splenectomy ondevelopment of primary amoebic meningoencephalitis.Korean J Parasitol 23", pp.156~164 (1985)
  126. "Immunological approachfor classification of free-living amoeba in Korea. Korean JParasitol 30", pp.289~298 (1992)
  127. "Cytotoxicity of Acanthamoebasp. YM-4", pp.31~38 (1993)
  128. "Evolution of eukaryotic microorganismsand their small subunit ribosomal RNAs. Am Zool 29", pp.487~499 (1989)
  129. "The protective effects of monoclonalantibodies in mice from Naegleria fowleri infection.Korean J Parasitol 30", pp.113~123 (1992)
  130. "Mycobacterium avium bacilli grow saprozoically in coculturewith Acanthamoeba polyphaga and survive withincyst walls. Appl Environ Microbiol 64", pp.2256~2261 (1998)
  131. "Variations in the propertiesand morphology of cysts of Acanthamoeba castellanii. JGen Microbiol 108", pp.33~37 (1978)
  132. "Pathogenic and enzymatic characteristics ofAcanthamoeba isolated from cultured tumor cells.Protistologica 15", pp.17~22 (1979)
  133. "Classification of Acanthamoeba. RevInfect Dis 13", pp.369~372 (1991)
  134. "Comparative studies onrelated free-living and pathogenic amebae with specialreference to Acanthamoeba. J Protozool 22", pp.245~256 (1975)
  135. "a new agentof amebic meningoencephalitis in humans and animals.J Clin Microbiol 28", pp.750~756 (1990)
  136. "agent of amebic meningoencephalitisin humans and other animals. J EukaryotMicrobiol 40", (sp.), pp.504~514 (1993)
  137. "Epidemiology of freelivingameba infections. J Protozool 37", pp.25~33 (1990)
  138. "Immunologic responseof mice against free-living amoeba", pp.259~273 (1980)
  139. "Primary amoebic meningoencephalitis. Aselected bibliography and tabular survey of cases. AnnSoc Belge Med Trop 54", pp.429~440 (1974)
  140. "Retrospective identificationof Acanthamoeba culbertsoni in a case of amoebicmeningoencephalitis. J Clin Pathol 31", pp.717~720 (1978)
  141. "Changes in the virulenceof Naegleria fowleri maintained in vitro. J Parasitol63", pp.872~878 (1977)
  142. "Phylogenetic relationshipsamong Acanthamoeba spp. based on PCR-RFLPanalyses of mitochondrial small subunit rRNA gene.", 37, pp.181~188. (1999)
  143. "Cloning of a cysteineproteinase gene from Acanthamoeba culbertsoni.", 9, pp.491~496 (1999)
  144. "Isolation ofgenes induced in Naegleria fowleri during mouse brainpassage.", 38, pp.105~111 (2002)

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