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Identification of differentially expressed cDNAs in Acanthamoeba culbertsoni after mouse brain passage

이종원|박순정|용태순|임경일|한규리|김돈수
대한기생충학ㆍ열대의학회 (The Korean Society For Parasitology and Tropical Medicine)|2006.03|Parasites, Hosts and Diseases|제44권 제1호|pp. 15-20

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참고문헌

주제분류예방의학/직업환경의학

초록

Abstract

Free-living amoebae of the genus Acanthamoeba are causative agents of granulomatous amebicencephalitis and amebic keratitis. Because the virulence of Acanthamoeba culbertsoni cultured in the laboratory isrestored by consecutive brain passages, we examined the genes induced in mouse brain-passaged A. culbertsonibydifferential display reverse transcriptase polymerase chain reaction (DDRT-PCR). Enhanced A. culbertsonivirulencewas observed during the second mouse brain passage, i.e., infected mouse mortality increased from 5% to 70%. TencDNAs induced during mouse brain passage were identified by DDRT-PCR and this was confirmed by northern blotanalysis. BlastX searches of these cDNAs indicated the upregulations of genes encoding predictive NADH-dehydro-genase, proteasomal ATPase, and GDP-mannose pyrophosphorylase B, which have previously been reported to beassociated with A. culbertsonivirulence factors.

참고문헌 (17)

  1. "Identification of Eimeria bovismerozoite cDNAsusing differential mRNA display", 71, pp.183~191 (1995)
  2. "Disruption of mannose activation in Leishmania mexicanaGDP-mannose pyrophosphory-lase is required for virulence, but not for viability.", 20, pp.3657~3666 (2001)
  3. "Analysis of the tumour suppressor ING1 expression andgene mutation in human basal cell carcinoma", 22, pp.927~931 (2003)
  4. "Medical and surgicaltreatment of Acanthamoeba", pp.604~607 (1987)
  5. "The proteasome of Mycobacterium tuberculosis is required for resistance to nitric oxide", 302, pp.1963~1966 (2003)
  6. "an ATP-dependent activator of the 20Sproteasome and ATPase is containing multiple mem-bers of nucleotide-binding protein family", pp.20878~20884 (1994)
  7. "Granulomatous amoebic encephalitis in an AIDSpatient", pp.~41
  8. "Proteolytic enzymes of pathogenicand non-pathogenic strains of Acanthamoebaspp"
  9. "The ubiquitin system.", 67, pp.425~479 (1998)
  10. "A proteasomal ATPase subunit recognizes", 18, pp.763~767 (2002)
  11. "Changes in the pathogenicityof Naegleria fowloweriby several brain passaged in mice", pp.234~240 (1983)
  12. "Protectionof chickens against experimental fowl typhoid using anuoG mutant of Salmonella serotype Gallinarum", 16, pp.899~903 (1998)
  13. "Differential display and cloning of mRNAs fromhuman breast cancer versus mammary epithelial cells", pp.6966~6968 (1992)
  14. "The effect of the passages ofAcanthamoebastrains through mice tissues on their viru-lence and its biochemical markers cDNAs in A", pp.431~ (1994)
  15. "Fasiola hepatica; Stage-specific expression of novel gene sequences as identified by differential display", 89, pp.169~179 (1998)
  16. "A rapid and simple PCR-based method for isolation of cDNA from differentiallyexpressed genes Theyeast FET5 gene encodes a FET3-related multicopperoxidase implicated in iron transport", pp.4009 547~4015 556
  17. "The yeast FET5 gene encodes a FET3-related multicopper oxidase implicated in iron transport", 256, pp.547~556 (1997)

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