Changes in Sonographic Findings after Treatment of Patients with Clonorchiasis in a Heavy Endemic Area
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초록
We measured changes in sonographic findings of patients with clonorchiasis after a treatment in a highly endemic area. A total of 347 residents showed positive stool results for Clonorchis sinensis eggs in a village in northeastern China, and were treated with praziquantel. Of them, 132 patients underwent abdominal sonography both before and 1 year after treatment, and the changes in sonographic findings of 83 cured subjects were compared. Diffuse dilatation of intrahepatic bile ducts (DDIHD) was found in 82 patients (98.2%) before and 80 (96.4%) after treatment, which was improved in 3, aggravated in 1, and unchanged in 79 patients. Increased periductal echogenicity (IPDE) was observed in 42 patients (50.6%) before and 45 (54.2%) after treatment, which was improved in 5, aggravated in 8, and unchanged in 70 patients. Floating echogenic foci in the gallbladder (FEFGB) was detected in 32 patients (38.6%) before and 17 (20.5%) after treatment, which was improved in 20, aggravated in 5, and unchanged in 58 patients. Improvement of FEFGB only was statistically significantly (P = 0.004). The present results confirm that DDIHD and IPDE persist but FEFGB decreases significantly at 1 year after treatment. In a heavy endemic area, the sonographic finding of FEFGB may suggest active clonorchiasis 1 year after treatment.
Abstract
We measured changes in sonographic findings of patients with clonorchiasis after a treatment in a highly endemic area. A total of 347 residents showed positive stool results for Clonorchis sinensis eggs in a village in northeastern China, and were treated with praziquantel. Of them, 132 patients underwent abdominal sonography both before and 1 year after treatment, and the changes in sonographic findings of 83 cured subjects were compared. Diffuse dilatation of intrahepatic bile ducts (DDIHD) was found in 82 patients (98.2%) before and 80 (96.4%) after treatment, which was improved in 3, aggravated in 1, and unchanged in 79 patients. Increased periductal echogenicity (IPDE) was observed in 42 patients (50.6%) before and 45 (54.2%) after treatment, which was improved in 5, aggravated in 8, and unchanged in 70 patients. Floating echogenic foci in the gallbladder (FEFGB) was detected in 32 patients (38.6%) before and 17 (20.5%) after treatment, which was improved in 20, aggravated in 5, and unchanged in 58 patients. Improvement of FEFGB only was statistically significantly (P = 0.004). The present results confirm that DDIHD and IPDE persist but FEFGB decreases significantly at 1 year after treatment. In a heavy endemic area, the sonographic finding of FEFGB may suggest active clonorchiasis 1 year after treatment.
참고문헌 (18)
- Rim HJ, "Clonorchiasis: an update", J Helminthol, 79, pp.269~281 (2005)
- Lee JH, "Heterogeneity of the ‘‘oval-cell’’ response in the hamster liver during cholangiocarcinogenesis following Clonorchis sinensis infection and dimethylnitrosamine treatment", J Hepatol, 26, pp.1313~1323 (1997)
- Choi BI, "Clonorchiasis and cholangiocarcinoma:etiologic relationship and imaging diagnosis", Clin Microbiol Rev, 17, pp.540~552 (2004)
- Choi D, "Cholangiocarcinoma and Clonorchis sinensis infection: a case-control study in Korea", J Hepatol, 44, pp.1066~1073 (2006)
- Lim MK, "Shin HR.Clonorchis sinensis infection and increasing risk of cholangiocarcinoma in the Republic of Korea", Am J Trop Med Hyg, 75, pp.93~96 (2006)
- Hong ST, "The Kato-Katz method is reliable for diagnosis of Clonorchis sinensis infection", Diagn Microbiol Infect Dis, 47, pp.345~347 (2003)
- Lim JH, "Clonorchiasis: sonographic findings in 59 proved cases", AJR Am J Roentgenol, 152, pp.761~764 (1989)
- Choi D, "Long-lasting sonographic and histopathological findings in cured clonorchiasis of rabbits", Korean J Parasitol, 37, pp.77~83 (1999)
- 최동일, "Imaging diagnosis of clonorchiasis", The Korean Journal of Parasitology, 45(2), pp.77~85 (2007), 대한기생충학회
- Lim JH, "Parasitic diseases of the biliary tract", AJR Am J Roentgenol, 188, pp.1596~1603 (2007)
- Hong ST, "Correlation of sonographic findings with histopathological changes of the bile ducts in rabbits infected with Clonorchis sinensis", Korean J Parasitol, 32, pp.223~230 (1994)
- Choi D, "Sonographic findings of active Clonorchis sinensis infection", J Clin Ultrasound, 32, pp.17~23 (2004)
- Choi MS, "Correlation between sonographic findings and infection intensity in clonorchiasis", Am J Trop Med Hyg, 73, pp.1139~1144 (2005)
- Hong ST, "Control of clonorchiasis by repeated praziquantel treatment and low diagnostic efficacy of sonography", Korean J Parasitol, 36, pp.249~254 (1998)
- Lee KH, "Experimental clonorchiasis in dogs: CT findings before and after treatment", Radiology, 228, pp.131~138 (2003)
- 최민호, "Correlation of egg counts of Clonorchis sinensis by three methods of fecal examination", The Korean Journal of Parasitology, 43(3), pp.115~117 (2005), 대한기생충학회
- Choi BI, "Peripheral cholangiocarcinoma and clonorchiasis: CT findings", Radiology, 169, pp.149~153 (1988)
- Yong Yeon Jeong, "MR Imaging Findings of Clonorchiasis", Korean Journal of Radiology, 5(1), pp.25~30 (2004), 대한영상의학회