Bedside Evaluation of Dizzy Patients
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In recent decades there has been marked progress in the imaging and laboratory evaluation of dizzy patients. However, detailed history taking and comprehensive bedside neurotological evaluation remain crucial for a diagnosis of dizziness. Bedside neurotological evaluation should include examinations for ocular alignment, spontaneous and gaze-evoked nystagmus, the vestibuloocular reflex, saccades, smooth pursuit, and balance. In patients with acute spontaneous vertigo,negative head impulse test, direction-changing nystagmus, and skew deviation mostly indicate central vestibular disorders. In contrast, patients with unilateral peripheral deafferentation invariably have a positive head impulse test and mixed horizontal-torsional nystagmus beating away from the lesion side. Since suppression by visual fixation is the rule in peripheral nystagmus and is frequent even in central nystagmus, removal of visual fixation using Frenzel glasses is required for the proper evaluation of central as well as peripheral nystagmus. Head-shaking, cranial vibration, hyperventilation, pressure to the external auditory canal, and loud sounds may disclose underlying vestibular dysfunction by inducing nystagmus or modulating the spontaneous nystagmus. In patients with positional vertigo, the diagnosis can be made by determining patterns of the nystagmus induced during various positional maneuvers that include straight head hanging, the Dix-Hallpike maneuver, supine head roll, and head turning and bending while sitting. Abnormal smooth pursuit and saccades, and severe imbalance also indicate central pathologies. Physicians should be familiar with bedside neurotological examinations and be aware of the clinical implications of the findings when evaluating dizzy patients.
Abstract
In recent decades there has been marked progress in the imaging and laboratory evaluation of dizzy patients. However, detailed history taking and comprehensive bedside neurotological evaluation remain crucial for a diagnosis of dizziness. Bedside neurotological evaluation should include examinations for ocular alignment, spontaneous and gaze-evoked nystagmus, the vestibuloocular reflex, saccades, smooth pursuit, and balance. In patients with acute spontaneous vertigo,negative head impulse test, direction-changing nystagmus, and skew deviation mostly indicate central vestibular disorders. In contrast, patients with unilateral peripheral deafferentation invariably have a positive head impulse test and mixed horizontal-torsional nystagmus beating away from the lesion side. Since suppression by visual fixation is the rule in peripheral nystagmus and is frequent even in central nystagmus, removal of visual fixation using Frenzel glasses is required for the proper evaluation of central as well as peripheral nystagmus. Head-shaking, cranial vibration, hyperventilation, pressure to the external auditory canal, and loud sounds may disclose underlying vestibular dysfunction by inducing nystagmus or modulating the spontaneous nystagmus. In patients with positional vertigo, the diagnosis can be made by determining patterns of the nystagmus induced during various positional maneuvers that include straight head hanging, the Dix-Hallpike maneuver, supine head roll, and head turning and bending while sitting. Abnormal smooth pursuit and saccades, and severe imbalance also indicate central pathologies. Physicians should be familiar with bedside neurotological examinations and be aware of the clinical implications of the findings when evaluating dizzy patients.
참고문헌 (69)
- Baloh RW, "Patient with dizziness, In Disorders of the Vestibular System", pp.157~170 (1996), Oxford University Press
- Leigh RJ, "The Neurology of Eye Movements" (2006), Oxford University Press
- Kattah JC, "HINTS to diagnose stroke in the acute vestibular syndrome: threestep bedside oculomotor examination more sensitive than early MRI diffusion-weighted imaging", Stroke, 40, pp.3504~3510 (2009)
- Tarnutzer AA, "Does my dizzy patient have a stroke? A systematic review of bedside diagnosis in acute vestibular syndrome", Canadian Medical Association Journal, 183, pp.E571~E592 (2011)
- Westheimer G, "The ocular tilt reaction--a brainstem oculomotor routine", Investigative Ophthalmology & Visual Science, 14, pp.833~839 (1975)
- Dieterich M, "Ocular torsion and tilt of subjective visual vertical are sensitive brainstem signs", Annals of Neurology, 33, pp.292~299 (1993)
- Diamond SG, "Ocular counterrolling as an indicator of vestibular otolith function", Neurology, 33, pp.1460~1469 (1983)
- Halmagyi GM, "Tonic contraversive ocular tilt reaction due to unilateral meso-diencephalic lesion", Neurology, 40, pp.1503~1509 (1990)
- Baier B, "Are signs of ocular tilt reaction in patients with cerebellar lesions mediated by the dentate nucleus?", Brain, 131(Pt 6), pp.1445~1454 (2008)
- Zwergal A, "A bucket of static vestibular function", Neurology, 72, pp.1689~1692 (2009)
- Serra A, "Diagnostic value of nystagmus: spontaneous and induced ocular oscillations", Journal of Neurology, Neurosurgery & Psychiatry, 73, pp.615~618 (2002)
- Baloh RW, "Clinical practice. Vestibular neuritis", The New England Journal of Medicine, 348, pp.1027~1032 (2003)
- Robinson DA, "Alexander’s law: its behavior and origin in the human vestibulo-ocular reflex", Annals of Neurology, 16, pp.714~722 (1984)
- Hotson JR, "Acute vestibular syndrome", The New England Journal of Medicine, 339, pp.680~685 (1998)
- Zee DS., "Ophthalmoscopy in examination of patients with vestibular disorders", Annals of Neurology, 3, pp.373~374 (1978)
- Baloh RW, "Spontaneous vertical nystagmus", Revue neurologique (Paris), 145, pp.527~532 (1989)
- Böhmer A, "Pathomechanism of mammalian downbeat nystagmus due to cerebellar lesion: a simple hypothesis", Neuroscience Letters, 250, pp.127~130 (1998)
- Baloh RW, "Downbeat nystagmus: a type of central vestibular nystagmus", Neurology, 31, pp.304~310 (1981)
- Glasauer S, "Threedimensional eye position and slow phase velocity in humans with downbeat nystagmus", Journal of Neurophysiology, 89, pp.338~354 (2003)
- Choi KD, "Recovery of vestibular imbalances after vestibular neuritis", The Laryngoscope, 117, pp.1307~1312 (2007)
- Büttner U, "Gaze-evoked nystagmus and smooth pursuit deficits: their relationship studied in 52 patients", Journal of Neurology, 242, pp.384~389 (1995)
- Lee H, "Cerebellar infarction presenting isolated vertigo: frequency and vascular topographical patterns", Neurology, 67, pp.1178~1183 (2006)
- Zapala DA., "Down-beating nystagmus in anterior canal benign paroxysmal positional vertigo", Journal of the American Academy of Audiology, 19, pp.257~266 (2008)
- Brantberg K, "Treatment of anterior benign paroxysmal positional vertigo by canal plugging: a case report", Acta Oto-Laryngologica, 122, pp.28~30 (2002)
- Shallo-Hoffmann J, "A reexamination of end-point and rebound nystagmus in normals", Investigative Ophthalmology & Visual Science, 31, pp.388~392 (1990)
- Choi KD, "Head-shaking nystagmus in lateral medullary infarction: patterns and possible mechanisms", Neurology, 68, pp.1337~1344 (2007)
- Hain TC, "Head-shaking nystagmus in patients with unilateral peripheral vestibular lesions", American Journal of Otolaryngology, 8, pp.36~47 (1987)
- Minagar A, "Perverted head-shaking nystagmus: a possible mechanism", Neurology, 57, pp.887~889 (2001)
- Kim JS, "Isolated perverted head-shaking nystagmus in focal cerebellar infarction", Neurology, 64, pp.575~576 (2005)
- Huh YE, "Patterns of spontaneous and head-shaking nystagmus in cerebellar infarction: imaging correlations", Brain, 134(Pt 12), pp.3662~3671 (2011)
- Choi KD, "Hyperventilation-induced nystagmus in vestibular schwannoma", Neurology, 64, pp.2062~ (2005)
- Robichaud J, "Is hyperventilation-induced nystagmus more common in retrocochlear vestibular disease than in end-organ vestibular disease?", Journal of Otolaryngology, 31, pp.140~143 (2002)
- Walker MF, "The effect of hyperventilation on downbeat nystagmus in cerebellar disorders", Neurology, 53, pp.1576~1579 (1999)
- Choi KD, "Hyperventilation- induced nystagmus in peripheral vestibulopathy and cerebellopontine angle tumor", Neurology, 69, pp.1050~1059 (2007)
- Karlberg M, "Vibration-induced ocular torsion and nystagmus after unilateral vestibular deafferentation", Brain, 126(Pt 4), pp.956~964 (2003)
- Ohki M, "Vibration-induced nystagmus in patients with vestibular disorders", Otolaryngology - Head and Neck Surgery, 129, pp.255~258 (2003)
- Nam J, "Ageotropic central positional nystagmus in nodular infarction", Neurology, 73, pp.1163~ (2009)
- Arai M, "Central paroxysmal positional vertigo", Neurology, 64, pp.1284~ (2005)
- Büttner U, "Diagnostic criteria for central versus peripheral positioning nystagmus and vertigo: a review", Acta Oto-Laryngologica, 119, pp.1~5 (1999)
- Fernandez C, "Experimental observations on postural nystagmus. II. Lesions of the nodulus", The Annals of Otology, Rhinology & Laryngology, 69, pp.94~114 (1960)
- Dix MR, "The pathology symptomatology and diagnosis of certain common disorders of the vestibular system", Proc R Soc Med, 45, pp.341~354 (1952)
- Baloh RW, "Benign positional vertigo: clinical and oculographic features in 240 cases", Neurology, 37, pp.371~378 (1987)
- Humphriss RL, "Contraindications to the Dix-Hallpike manoeuvre: a multidisciplinary review", International Journal of Audiology, 42, pp.166~173 (2003)
- Cohen HS, "Side-lying as an alternative to the Dix-Hallpike test of the posterior canal", Otology & Neurotology, 25, pp.130~134 (2004)
- McClure JA, "Horizontal canal BPV", Journal of Otolaryngology, 14, pp.30~35 (1985)
- Baloh RW, "Persistent directionchanging positional nystagmus: another variant of benign positional nystagmus?", Neurology, 45, pp.1297~1301 (1995)
- Koo JW, "Value of lying-down nystagmus in the lateralization of horizontal semicircular canal benign paroxysmal positional vertigo", Otology & Neurotology, 27, pp.367~371 (2006)
- Lee SH, "Nystagmus during neck flexion in the pitch plane in benign paroxysmal positional vertigo involving the horizontal canal", Journal of the Neurological Sciences, 256, pp.75~80 (2007)
- Bisdorff AR, "Localizing signs in positional vertigo due to lateral canal cupulolithiasis", Neurology, 57, pp.1085~1088 (2001)
- Minor LB, "Sound- and", or pressureinduced vertigo due to bone dehiscence of the superior semicircular canal, 1998, pp.124, 249~258
- Tilikete C, "Pulse-synchronous eye oscillations revealing bone superior canal dehiscence", Annals of Neurology, 56, pp.556~560 (2004)
- Halmagyi GM, "A clinical sign of canal paresis", Archives of neurology, 45, pp.737~739 (1988)
- Weber KP, "Head impulse test in unilateral vestibular loss: vestibulo-ocular reflex and catch-up saccades", Neurology, 70, pp.454~463 (2008)
- Cremer PD, "Semicircular canal plane head impulses detect absent function of individual semicircular canals", Brain, 121(Pt 4), pp.699~716 (1998)
- Newman-Toker DE, "Normal head impulse test differentiates acute cerebellar strokes from vestibular neuritis", Neurology, 70(24 Pt 2), pp.2378~2385 (2008)
- Walker MF, "Directional abnormalities of vestibular and optokinetic responses in cerebellar disease", Annals of the New York Academy of Sciences, 871, pp.205~220 (1999)
- Walker MF, "Cerebellar disease alters the axis of the high-acceleration vestibuloocular reflex", Journal of Neurophysiology, 94, pp.3417~3429 (2005)
- Jeong SH, "Perverted head impulse test in cerebellar ataxia", The Cerebellum (2013)
- Perez N, "Head-impulse and caloric tests in patients with dizziness", Otology & Neurotology, 24, pp.913~917 (2003)
- Kim S, "Bilateral vestibulopathy: clinical characteristics and diagnostic criteria", Otology & Neurotology, 32, pp.812~817 (2011)
- Ramat S, "Translational vestibulo-ocular reflex evoked by a “head heave” stimulus", Annals of the New York Academy of Sciences, 942, pp.95~113 (2001)
- Gaymard B, "Neurology of saccades and smooth pursuit", Current Opinion in Neurology, 12, pp.13~19 (1999)
- Sharpe JA, "Midbrain disorders of vertical gaze: a quantitative re-evaluation", Annals of the New York Academy of Sciences, 956, pp.143~154 (2002)
- Robinson FR, "Role of the caudal fastigial nucleus in saccade generation. II. Effects of muscimol inactivation", Journal of Neurophysiology, 70, pp.1741~1758 (1993)
- Takagi M, "Effects of lesions of the oculomotor vermis on eye movements in primate: saccades", Journal of Neurophysiology, 80, pp.1911~1931 (1998)
- Helmchen C, "Saccadic lateropulsion in Wallenberg’s syndrome may be caused by a functional lesion of the fastigial nucleus", Journal of Neurology, 241, pp.421~426 (1994)
- Chen L, "Diagnostic accuracy of acute vestibular syndrome at the bedside in a stroke unit", Journal of Neurology, 258, pp.855~861 (2011)
- Cnyrim CD, "Bedside differentiation of vestibular neuritis from central “vestibular pseudoneuritis”", Journal of Neurology, Neurosurgery & Psychiatry, 79, pp.458~460 (2008)
- Dieterich M, "Direction-specific impairment of motion perception and spatial orientation in downbeat and upbeat nystagmus in humans", Neuroscience Letters, 245, pp.29~32 (1998)
