First Case of Canine Infection with Hepatozoon canis (Apicomplexa: Haemogregarinidae) in the Republic of Korea
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This report describes a dog infected with Hepatozoon canis, the first canine infection in the Republic of Korea. A 2-year-old intact male Maltese dog presented with anorexia and depression. Physical examinations revealed mild dehydration and hyperthermia (39.8°C), and blood analysis showed pancytopenia. Diff-Quik staining of blood smear specimens showed the presence of ellipsoidal shaped structures (gamonts of H. canis) within a small number of neutrophils. Real-time PCR analysis using whole blood confirmed infection by H. canis. The clinical condition of the dog improved after symptomatic treatment and administration of doxycycline. Although a molecular epidemiologic survey in Korea showed H. canis infection of dogs, to our knowledge this is the first report of a dog infection in Korea molecularly shown to be H. canis.
Abstract
This report describes a dog infected with Hepatozoon canis, the first canine infection in the Republic of Korea. A 2-year-old intact male Maltese dog presented with anorexia and depression. Physical examinations revealed mild dehydration and hyperthermia (39.8°C), and blood analysis showed pancytopenia. Diff-Quik staining of blood smear specimens showed the presence of ellipsoidal shaped structures (gamonts of H. canis) within a small number of neutrophils. Real-time PCR analysis using whole blood confirmed infection by H. canis. The clinical condition of the dog improved after symptomatic treatment and administration of doxycycline. Although a molecular epidemiologic survey in Korea showed H. canis infection of dogs, to our knowledge this is the first report of a dog infection in Korea molecularly shown to be H. canis.
참고문헌 (24)
- Greene CE, "Infectious Diseases of The Dog and Cat", pp.750~757 (2012), Elsevier Saunders
- Baneth G, "Canine hepatozoonosis : two disease syndromes caused by separate Hepatozoon spp", Trends Parasitol, 19, pp.27~31 (2003)
- Baneth G, "Transmission of Hepatozoon canis to dogs by naturally-fed or percutaneouslyinjected Rhipicephalus sanguineus ticks", J Parasitol, 87, pp.606~611 (2001)
- Smith TG, "The genus Hepatozoon(Apicomplexa : Adeleina)", J Parasitol, 82, pp.565~585 (1996)
- Baneth G, "Life cycle of Hepatozoon canis (Apicomplexa: Adeleorina: Hepatozoidae) in the tick Rhipicephalus sanguineus and domestic dog (Canis familiaris)", J Parasitol, 93, pp.283~299 (2007)
- Vincent-Johnson NA, "A new Hepatozoon species from dogs : description of the causative agent of canine hepatozoonosis in North America", J Parasitol, 83, pp.1165~1172 (1997)
- Baneth G, "Genetic and antigenic evidence supports the separation of Hepatozoon canis and Hepatozoon americanum at the species level", J Clin Microbiol, 38, pp.1298~1301 (2000)
- Kwak DH, "Molecular survey of Babesia gibsoni and Hepatozoon canis infection in dogs from Jeju island", J Vet Clin, 10, pp.154~ (2008)
- Kubo M, "The first report of Hepatozoon species infection in leopard cats (Prionailurus bengalensis) in Korea", J Parasitol, 96, pp.437~439 (2010)
- Baneth G, "Retrospective case-control study of Hepatozoonosis in dogs in Israel", J Vet Intern Med, 11, pp.365~370 (1997)
- Otranto D, "Diagnosis of Hepatozoon canis in young dogs by cytology and PCR", Parasit Vectors, 4, pp.55~ (2011)
- Li Y, "Diagnosis of canine Hepatozoon spp. infection by quantitative PCR", Vet Parasitol, 157, pp.50~58 (2008)
- Gonen L, "An enzyme-linked immunosorbent assay for antibodies to Hepatozoon canis", Vet Parasitol, 122, pp.131~139 (2004)
- James SP, "On a parasite found in the white corpuscles of the blood of dogs", Sci Mem Offrs Med Sanit Deps India, 14, pp.1~12 (1905)
- Craig TM, "Hepatozoon canis infection in dogs: clinical, radiographic, and hematologic findings", J Am Vet Med Assoc, 173, pp.967~972 (1978)
- Nordgren RM, "Experimental transmission of the Texas strain of Hepatozoon canis", Vet Parasitol, 16, pp.207~214 (1984)
- Dantas-Torres F, "The brown dog tick, Rhipicephalus sanguineus (Latreille, 1806) (Acari: Ixodidae): from taxonomy to control", Vet Parasitol, 152, pp.173~185 (2008)
- Kim CM, "Tick-borne rickettsial pathogens in ticks and small mammals in Korea", Appl Environ Microbiol, 72, pp.5766~5776 (2006)
- Heung Chul Kim, "Ticks Collected from Selected Mammalian Hosts Surveyed in the Republic of Korea During 2008-2009", The Korean Journal of Parasitology, 49(3), pp.331~335 (2011), 대한기생충학ㆍ열대의학회
- Studies on tick eradication in Korea (1982-1984). Special project for animal health, "Kang YB", Ann Rep Inst Vet Res, Rural Develop Admin, 269~305 (1984)
- Murata T, "Detection of Hepatozoon canis oocyst from ticks collected from the infected dogs", J Vet Med Sci, 57, pp.111~112 (1995)
- Karagenc TI, "A parasitological, molecular and serological survey of Hepatozoon canis infection in dogs around the Aegean coast of Turkey", Vet Parasitol, 135, pp.113~119 (2006)
- Ibrahim ND, "Neutrophil myeloperoxidase deficiency associated with canine hepatozoonosis", Int J Parasitol, 19, pp.915~918 (1989)
- Murata T, "Investigation of nitroblue tetrazolium reduction of neutrophils in the dog infected with Hepatozoon canis", Jikken Dobutsu, 43, pp.101~103 (1994)