Primary Amebic Meningoencephalitis: A Case Report
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Primary amebic encephalitis (PAM) is a devastating central nervous system infection caused by Naegleria fowl- eri, a free-living amoeba, which can survive in soil and warm fresh water. Here, a 43-year-old healthy male was exposed to warm freshwater 5 days before the symptom onset. He rapidly developed severe cerebral edema before the diagnosis of PAM and was treated with intravenous conventional amphotericin B while died of terminal cerebral hernia finally. Com- paring the patients with PAM who has similar clinical symptoms to those with other common types of meningoencephali- tis, this infection is probably curable if treated early and aggressively. PAM should be considered in the differential diagno- sis of purulent meningoencephalitis, especially in patients with recent freshwater-related activities during the hot season.
Abstract
Primary amebic encephalitis (PAM) is a devastating central nervous system infection caused by Naegleria fowl- eri, a free-living amoeba, which can survive in soil and warm fresh water. Here, a 43-year-old healthy male was exposed to warm freshwater 5 days before the symptom onset. He rapidly developed severe cerebral edema before the diagnosis of PAM and was treated with intravenous conventional amphotericin B while died of terminal cerebral hernia finally. Com- paring the patients with PAM who has similar clinical symptoms to those with other common types of meningoencephali- tis, this infection is probably curable if treated early and aggressively. PAM should be considered in the differential diagno- sis of purulent meningoencephalitis, especially in patients with recent freshwater-related activities during the hot season.
참고문헌 (11)
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