Prevalence and Risk Factors of Intestinal Helminthiasis in Remote Mountainous Villages of Northern Lao PDR: A Cross-Sectional Study
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Helminth infections are prevalent in Lao People’s Democratic Republic (Lao PDR). This study aimed at deter- mining the prevalence and risk factors of intestinal helminthiasis in remote mountainous villages of northern Lao PDR. During the dry season in January 2017, a cross-sectional survey was conducted in 3 remote mountainous villages in Ou- domxay province, Lao PDR. Villagers older than 18 years of age who agreed to submit stool samples or undergo an inter- view, were recruited. Stool samples from 198 individuals were examined by the Kato-Katz method, and a questionnaire surveyed 161 individuals among them. Univariable and multivariable logistic regression analyses were used to identify risk factors associated with the intestinal helminthiasis. An overall prevalence of intestinal helminthiasis was 75.8%. Hook- worm infection was the most common (63.1%), followed by Opisthorchis viverrini/minute intestinal flukes (17.7%), Taenia spp. (15.2%), Trichuris trichiura (2.0%), Ascaris lumbricoides (1.5%), and Enterobius vermicularis (1.0%). Questionnaire analysis revealed sex (male) and absence of latrine to be significant risk factors for hookworm infection and consumption of raw meat for taeniasis. These results suggest that the mountainous area in northern Lao PDR has a different composi- tion of helminth infections from other studies conducted in Lao PDR; a high prevalence of hookworm infection and taeni- asis and low prevalence of T. trichiura and A. lumbricoides infections were observed. Also, liver flukes or intestinal flukes were similarly prevalent in the mountainous area
Abstract
Helminth infections are prevalent in Lao People’s Democratic Republic (Lao PDR). This study aimed at deter- mining the prevalence and risk factors of intestinal helminthiasis in remote mountainous villages of northern Lao PDR. During the dry season in January 2017, a cross-sectional survey was conducted in 3 remote mountainous villages in Ou- domxay province, Lao PDR. Villagers older than 18 years of age who agreed to submit stool samples or undergo an inter- view, were recruited. Stool samples from 198 individuals were examined by the Kato-Katz method, and a questionnaire surveyed 161 individuals among them. Univariable and multivariable logistic regression analyses were used to identify risk factors associated with the intestinal helminthiasis. An overall prevalence of intestinal helminthiasis was 75.8%. Hook- worm infection was the most common (63.1%), followed by Opisthorchis viverrini/minute intestinal flukes (17.7%), Taenia spp. (15.2%), Trichuris trichiura (2.0%), Ascaris lumbricoides (1.5%), and Enterobius vermicularis (1.0%). Questionnaire analysis revealed sex (male) and absence of latrine to be significant risk factors for hookworm infection and consumption of raw meat for taeniasis. These results suggest that the mountainous area in northern Lao PDR has a different composi- tion of helminth infections from other studies conducted in Lao PDR; a high prevalence of hookworm infection and taeni- asis and low prevalence of T. trichiura and A. lumbricoides infections were observed. Also, liver flukes or intestinal flukes were similarly prevalent in the mountainous area
참고문헌 (30)
- Han-Jong Rim, "Prevalence of intestinal parasite infections on a national scale among primary schoolchildren in Laos", Parasitology Research, 91(4), pp.267~272 (2003), Springer Science and Business Media LLC[DOI]
- Keeseon S. Eom, "Prevalence of helminthic infections among inhabitants of Lao PDR", The Korean Journal of Parasitology, 52(1), pp.51~56 (2014), 대한기생충학ㆍ열대의학회[DOI]
- Youthanavanh Vonghachack, "Transmission of Opisthorchis viverrini, Schistosoma mekongi and soil-transmitted helminthes on the Mekong Islands, Southern Lao PDR", Infectious Diseases of Poverty, 6(1), pp.131~ (2017), Springer Science and Business Media LLC[DOI]
- R. C. Andrew Thompson, "Soil-Transmitted Helminthiasis in Laos: A Community-Wide Cross-Sectional Study of Humans and Dogs in a Mass Drug Administration Environment", The American Journal of Tropical Medicine and Hygiene, 86(4), pp.624~634 (2012), American Society of Tropical Medicine and Hygiene[DOI]
- James V. Conlan, "A Cross-Sectional Study of Taenia solium in a Multiple Taeniid-Endemic Region Reveals Competition May be Protective", The American Journal of Tropical Medicine and Hygiene, 87(2), pp.281~291 (2012), American Society of Tropical Medicine and Hygiene[DOI]
- Amanda Ash, "Controlling Taenia solium and soil transmitted helminths in a northern Lao PDR village: Impact of a triple dose albendazole regime", Acta Tropica, 174, pp.171~178 (2017), Elsevier BV[DOI]
- MoH L, "Diagnosis and Treatment in District Hospitals, Ministry of Health Lao PDR", pp.109~181 (2004)
- Sung-Tae Hong, "The Kato-Katz method is reliable for diagnosis of Clonorchis sinensis infection", Diagnostic Microbiology and Infectious Disease, 47(1), pp.345~347 (2003), Elsevier BV[DOI]
- "logistf: Firth's bias reduced logistic regression. R package version 1.22"[URL]
- Tiaoying Li, "Usefulness of pumpkin seeds combined with areca nut extract in community-based treatment of human taeniasis in northwest Sichuan Province, China", Acta Tropica, 124(2), pp.152~157 (2012), Elsevier BV[DOI]
- ANA FLISSER, "EVALUATION OF A SELF-DETECTION TOOL FOR TAPEWORM CARRIERS FOR USE IN PUBLIC HEALTH", The American Journal of Tropical Medicine and Hygiene, 72(5), pp.510~512 (2005), American Society of Tropical Medicine and Hygiene[DOI]
- Jeffrey Bethony, "Emerging patterns of hookworm infection: influence of aging on the intensity of Necator infection in Hainan Province, People's Republic of China", Clin Infect Dis, 35(11), pp.1336~1344 (2002), Oxford University Press (OUP)[DOI]
- Jeffrey Bethony, "Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm", The Lancet, 367(9521), pp.1521~1532 (2006), Elsevier BV[DOI]
- Jiraanankul V, "Incidence and risk factors of hookworm infection in a rural community of central Thailand", Am J Trop Med Hyg, 84, pp.594~598 (2011)[DOI]
- A. OLSEN, "A STUDY OF RISK FACTORS FOR INTESTINAL HELMINTH INFECTIONS USING EPIDEMIOLOGICAL AND ANTHROPOLOGICAL APPROACHES", Journal of Biosocial Science, 33(4), pp.569~584 (2001), Cambridge University Press (CUP)[DOI]
- Rebecca J. Traub, "The prevalence, intensities and risk factors associated with geohelminth infection in tea-growing communities of Assam, India", Tropical Medicine and International Health, 9(6), pp.688~701 (2004), Wiley[DOI]
- Bounlay Phommasack, "Coverage and costs of a school deworming programme in 2007 targeting all primary schools in Lao PDR", Transactions of the Royal Society of Tropical Medicine and Hygiene, 102(12), pp.1201~1206 (2008), Oxford University Press (OUP)[DOI]
- "Control of Foodborne Trematode Infections: Report of a WHO Study Group" (1995)[URL]
- Boualy Keokhamphavanh, "Current Status of Human Hookworm Infections, Ascariasis, Trichuriasis, Schistosomiasis Mekongi and Other Trematodiases in Lao People's Democratic Republic", The American Journal of Tropical Medicine and Hygiene, 90(4), pp.667~669 (2014), American Society of Tropical Medicine and Hygiene[DOI]
- Woon-Mok Sohn, "Prevalence of Haplorchis taichui among humans and fish in Luang Prabang Province, Lao PDR", Acta Tropica, 136, pp.74~80 (2014), Elsevier BV[DOI]
- Tai-Soon Yong, "Risk Factors for Opisthorchis viverrini and Minute Intestinal Fluke Infections in Lao PDR, 2009–2011", The American Journal of Tropical Medicine and Hygiene, 91(2), pp.384~388 (2014), American Society of Tropical Medicine and Hygiene[DOI]
- Armelle Forrer, "Spatial Distribution of, and Risk Factors for, Opisthorchis viverrini Infection in Southern Lao PDR", PLoS Neglected Tropical Diseases, 6(2), pp.e1481~ (2012), Public Library of Science (PLoS)[DOI]
- Khampheng Phongluxa, "Helminth infection in southern Laos: high prevalence and low awareness", Parasites & Vectors, 6(1), pp.328~ (2013), Springer Science and Business Media LLC[DOI]
- Conlan J, "A review of taeniasis and cysticercosis in the Lao People's Democratic Republic", Parasitol Int, 57, pp.252~255 (2008)[DOI]
- 채종일, "Prevalence of the Intestinal Flukes Haplorchis taichui and H. yokogawai in a Mountainous Area of Phongsaly Province, Lao PDR", The Korean Journal of Parasitology, 48(4), pp.339~342 (2010), 대한기생충학ㆍ열대의학회
- 임한종, "Fishborne Trematode Metacercariae in Luang Prabang, Khammouane, and Saravane Province, Lao PDR", The Korean Journal of Parasitology, 51(1), pp.107~114 (2013), 대한기생충학ㆍ열대의학회
- Pawlowski Z, "Taeniasis and cysticercosis (Taenia sagi-nata)", Adv Parasitol, 10, pp.269~343 (1972)[DOI]
- Andrew Hall, "Taenia saginata (Cestoda) in western Kenya: the reliability of faecal examinations in diagnosis", Parasitology, 83(1), pp.91~101 (1981), Cambridge University Press (CUP)[DOI]
- FRANCIS RAOUL, "Advances in diagnosis and spatial analysis of cysticercosis and taeniasis", Parasitology, 140(13), pp.1578~1588 (2013), Cambridge University Press (CUP)[DOI]
- Anna Okello, "Investigating a hyper-endemic focus of Taenia solium in northern Lao PDR", Parasites & Vectors, 7(1), pp.134~ (2014), Springer Science and Business Media LLC[DOI]