Status of Helminthic Infections in Residents around River Basins in the Republic of Korea for 10 Years (2011-2020)
2
조회
0
다운로드
3
인용
0
참고문헌
키워드
초록
The positive rate of Clonorchis sinensis is the highest among intestinal parasites in the Republic of Korea (Korea). More than 1.2 million people were at risk of C. sinensis infection in Korea in 2012. An intensive control program is being implemented for residents of the 5 major river basins to reduce helminthic infections, including C. sinensis infection. This study evaluated the continuous intensive control program for parasitic diseases including clonorchiasis in areas near the 5 major river basins in Korea over the past 10 years (2011-2020). A total of 335,020 fecal samples (one sample per resident) prepared by the modified sedimentation technic were microscopically examined. Those who expelled helminth eggs were treated with anthelmintics through local health centers and re-examined 3 months later. The overall positive rate of helminths egg was 7.1%. The annual positive rates were dramatically decreased from 14.4% (2011) to 5.9% (2020). The egg positive rate was highest in C. sinensis (5.3%), followed by heterophyid flukes (1.5%) and Trichuris trichiura (0.2%). The prevalence of C. sinensis was significantly higher in males (7.6%) than in females (3.7%), and the highest in the 50–59 years (7.0%) age group. Our results are beneficial to establish prevention and control policies against helminthiases including clonorchiasis in endemic areas in this country.
Abstract
The positive rate of Clonorchis sinensis is the highest among intestinal parasites in the Republic of Korea (Korea). More than 1.2 million people were at risk of C. sinensis infection in Korea in 2012. An intensive control program is being implemented for residents of the 5 major river basins to reduce helminthic infections, including C. sinensis infection. This study evaluated the continuous intensive control program for parasitic diseases including clonorchiasis in areas near the 5 major river basins in Korea over the past 10 years (2011-2020). A total of 335,020 fecal samples (one sample per resident) prepared by the modified sedimentation technic were microscopically examined. Those who expelled helminth eggs were treated with anthelmintics through local health centers and re-examined 3 months later. The overall positive rate of helminths egg was 7.1%. The annual positive rates were dramatically decreased from 14.4% (2011) to 5.9% (2020). The egg positive rate was highest in C. sinensis (5.3%), followed by heterophyid flukes (1.5%) and Trichuris trichiura (0.2%). The prevalence of C. sinensis was significantly higher in males (7.6%) than in females (3.7%), and the highest in the 50–59 years (7.0%) age group. Our results are beneficial to establish prevention and control policies against helminthiases including clonorchiasis in endemic areas in this country.
참고문헌 (23)
- Rachel L Pullan, "Global numbers of infection and disease burden of soil transmitted helminth infections in 2010", Parasites & Vectors, 7(1), pp.37~ (2014), Springer Science and Business Media LLC[DOI]
- "Soil-transmitted helminth infections"[URL]
- 김동수, "A Nationwide Survey on the Prevalence of Intestinal Parasitic Infections in the Republic of Korea, 2004", Parasites, Hosts and Diseases, 47(1), pp.37~47 (2009), 대한기생충학ㆍ열대의학회
- National survey of the prevalence of intestinal parasitic infections in Korea, the 8th report, "Korea Centers for Disease Control and Prevention", Korea Center for Disease Control and Prevention, ~ (2013)
- S J Hong, "Egg positive rates of Clonorchis sinensis and intestinal helminths among residents in Kagye-ri, Saengbiryang-myon, Sanchong-gun, Kyongsangnam-do", The Korean Journal of Parasitology, 32(4), pp.271~273 (1994), Korean Society for Parasitology[DOI]
- J R Yu, "Clonorchiasis and metagonimiasis in the inhabitants along Talchongang (River), Chungwon-gun", The Korean Journal of Parasitology, 32(4), pp.267~ (1994), Korean Society for Parasitology[DOI]
- C Y Joo, "Changing patterns of Clonorchis sinensis infections in Kyongbuk, Korea", The Korean Journal of Parasitology, 35(3), pp.155~164 (1997), Korean Society for Parasitology[DOI]
- JY Chai, "Two endemic foci of heterophyids and other intestinal fluke infections in southern and western coastal areas in Korea", The Korean Journal of Parasitology, 36(3), pp.155~ (1998), Korean Society for Parasitology[DOI]
- Young-Il Jeong, "Prevalence of Clonorchis sinensis Infection among Residents along 5 Major Rivers in the Republic of Korea", Parasites, Hosts and Diseases, 54(2), pp.215~219 (2016), 대한기생충학ㆍ열대의학회
- Sung-Tae Hong, "Clonorchis sinensis and clonorchiasis, an update", Parasitology International, 61(1), pp.17~24 (2012), Elsevier BV[DOI]
- Byong Seol Seo, "Study on the status of helminthic infections in Koreans", The Korean Journal of Parasitology, 7(1), pp.53~70 (1969), Korean Society for Parasitology[DOI]
- Huh S, "Intestinal parasitic infections of Korean Army soldiers in Whachon-gun, Korea", Korean J Parasitol, 31, pp.293~294 (1993)[DOI]
- Park MS, "Intestinal parasite infections in the inhabitants along the Hantan river, Chorwon-gun", Korean J Parasitol, 31, pp.375~378 (1993)[DOI]
- Hee-Eun Shin, "Epidemiological and Clinical Parameters Features of Patients with Clonorchiasis in the Geum River Basin, Republic of Korea", Interdisciplinary Perspectives on Infectious Diseases, 2017, pp.1~7 (2017), Hindawi Limited[DOI]
- IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, "A review of human carcinogens. Part B: biological agents" (2012), International Agency for Research on Cancer
- Byong Seol Seo, "An epidemiologic study on clonorchiasis and metagonimiasis in riverside areas in Korea", The Korean Journal of Parasitology, 19(2), pp.137~150 (1981), Korean Society for Parasitology[DOI]
- Yu SH, "Epidemiological investigation on Clonorchis sinensis in human population in an area of South China", Jpn J Infect Dis, 56, pp.168~171 (2003)
- "Provisional Agenda of the Fifty-Fourth World Health Assembly"[URL]
- 홍성태, "A successful experience of soil-transmitted helminth control in the Republic of Korea", Parasites, Hosts and Diseases, 44(3), pp.177~185 (2006), 대한기생충학ㆍ열대의학회
- "Infectious Disease Portal"[URL]
- Byoung-Kuk Na, "Clonorchis sinensis and clonorchiasis", Acta Tropica, 203, pp.105309~ (2020), Elsevier BV[DOI]
- 김춘미, "영산강 유역 주민의 간흡충 감염실태와 감염 예방교육 프로그램의 효과", 지역사회간호학회지, 22(1), pp.56~65 (2011), 한국지역사회간호학회
- 이상은, "Risk Factors of Clonorchis sinensis Human Infections in Endemic Areas, Haman-Gun, Republic of Korea: A Case-Control Study", Parasites, Hosts and Diseases, 58(6), pp.647~652 (2020), 대한기생충학ㆍ열대의학회[DOI]