Toxoplasma gondii IST suppresses inflammatory and apoptotic responses by inhibiting STAT1-mediated signaling in IFN-γ/TNF-α-stimulated hepatocytes

키워드

참고문헌 (35)

1. Lee JH, "Expression of cytokines and co-stimulatory molecules in the Toxoplasma gondii-infected dendritic cells of C57BL", 6 and BALB, Parasites Hosts Dis, pp.2023, 61(2)[DOI]
2. Kim GH, "Elevated interleukin-10 levels in patients with ocular toxoplasmosis", Parasites Hosts Dis, 61(3), pp.310~ (2023)[DOI]
3. Seo SH, "PTEN", AKT signaling pathway related to hTERT downregulation and telomere shortening induced in Toxoplasma GRA16-expressing colorectal cancer cells, 2022, pp.153, 113366~
4. Zhang Y, "Toxoplasma gondii secretory proteins and their role in invasion and pathogenesis", Microbiol Res, 227, pp.126293~ (2019)[DOI]
5. Kim SG, "Increase in the nuclear localization of PTEN by the Toxoplasma GRA16protein and subsequent induction of p53-dependent apoptosis and anticancer effect", J Cell Mol Med, 23(5), pp.3234~3245 (2019)[DOI]
6. Seo SH, "Toxoplasma gra16 inhibits nf-κb activation through pp2a-b55 upregulation in non-small-cell lung carcinoma cells", Int J Mol Sci, 21(18), pp.6642~ (2020)[DOI]
7. Krishnamurthy S, "Toxoplasma does not secrete the GRA16 and GRA24 effectors beyond the parasitophorous vacuole membrane of tissue cysts", Front Cell Infect Microbiol, 8, pp.366~ (2018)[DOI]
8. Olias P, "Toxoplasma effector recruits the Mi-2", NuRD complex to repress STAT1 transcription and block IFN-γ-dependent gene expression, 2016, pp.20(1), 72~82
9. Sasai M, "Innate, adaptive, and cell-autonomous immunity against Toxoplasma gondii infection", Exp Mol Med, 51(12), pp.1~10 (2019)[DOI]
10. Seizova S, "Transcriptional modification of host cells harboring Toxoplasma gondii bradyzoites prevents IFN gamma-mediated cell death", Cell Host Microbe, 30(2), pp.232~247 (2022)[DOI]
11. Xu Y, "Human endoderm stem cells reverse inflammation-related acute liver failure through cystatin SN-mediated inhibition of interferon signaling", Cell Res, 33(2), pp.147~164 (2023)[DOI]
12. Kubes P, "Sterile inflammation in the liver", Gastroenterology, 143(5), pp.1158~1172 (2012)[DOI]
13. Wesemann DR, "STAT-1α and IFN-γ as modulators of TNF-α signaling in macrophages : regulation and functional implications of the TNF receptor 1 : STAT-1α complex", J Immunol, 171(10), pp.5313~5319 (2003)[DOI]
14. Sutti S, "The role of immune mechanisms in alcoholic and nonalcoholic steatohepatitis : a 2015 update", Expert Rev Gastroenterol Hepatol, 10(2), pp.243~253 (2016)[DOI]
15. Woolbright BL, "Generation of pro-and anti-inflammatory mediators after acetaminophen overdose in surviving and non-surviving patients", Toxicol Lett, 367, pp.59~66 (2022)[DOI]
16. Tiegs G, "TNF in the liver : targeting a central player in inflammation", Semin Immunopathol, 44(4), pp.445~459 (2022)[DOI]
17. Olias P, "Toxoplasma effector recruits the Mi-2", NuRD complex to repress STAT1 transcription and block IFN-γ-dependent gene expression, 2016, pp.20(1), 72~82
18. Huang Z, "The intrinsically disordered protein TgIST from Toxoplasma gondii inhibits STAT1 signaling by blocking cofactor recruitment", Nat Commun, 13(1), pp.4047~ (2022)[DOI]
19. Krause CD, "Modulation of the activation of Stat1 by the interferon-γ receptor complex", Cell Res, 16(1), pp.113~123 (2006)[DOI]
20. Bassiony H, "Magnetite nanoparticles inhibit tumor growth and upregulate the expression of P53", P16 in Ehrlich solid carcinoma bearing mice, 2014, pp.9(11), e111960~
21. Davey GM, "SOCS1 : a potent and multifaceted regulator of cytokines and cell-mediated inflammation", Tissue Antigens, 67(1), pp.1~9 (2006)[DOI]
22. Liu W, "The immunological mechanisms and immune-based biomarkers of drug-induced liver injury", Front Pharmacol, 12, pp.723940~ (2021)[DOI]
23. Hosack T, "Drug-induced liver injury : a comprehensive review", Therap Adv Gastroenterol, 16, pp.17562848231163410~ (2023)[DOI]
24. Katarey D, "Drug-induced liver injury", Clin Med(Lond), 16(suppl), pp.104~109 (2016)[DOI]
25. Tasnim F, "Recent advances in models of immune-mediated drug-induced liver injury", Front Toxicol, 3, pp.605392~ (2021)[DOI]
26. Karki R, "Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes", Cell, 184(1), pp.149~168 (2021)[DOI]
27. Bradham CA, "Mechanisms of hepatic toxicity. I. TNF-induced liver injury", Am J Physiol, 275(3), pp.G387~G392 (1998)[DOI]
28. Tomita K, "Mixed lineage kinase 3 mediates the induction of CXCL10by a STAT1-dependent mechanism during hepatocyte lipotoxicity", J Cell Biochem, 118(10), pp.3249~3259 (2017)[DOI]
29. Iwanaszko M, "NF-κB and IRF pathways : crossregulation on target genes promoter level", BMC Genomics, 16(1), pp.1~8 (2015)[DOI]
30. Shanmugam N, "Regulation of cyclooxygenase-2 expression in monocytes by ligation of the receptor for advanced glycation end products", J Biol Chem, 278(37), pp.34834~34844 (2003)[DOI]
31. Song X, "CXCL9 regulates acetaminophen‑induced liver injury via CXCR3", Exp Ther Med, 18(6), pp.4845~4851 (2019)[DOI]
32. van Loo G, "Death by TNF : a road to inflammation", Nat Rev Immunol, 23(5), pp.289~303 (2023)[DOI]
33. Jaeschke H, "Mechanisms and pathophysiological significance of sterile inflammation during acetaminophen hepatotoxicity", Food Chem Toxicol, 138, pp.111240~ (2020)[DOI]
34. Gerussi A, "Immune-mediated drug-induced liver injury : immunogenetics and experimental models", Int J Mol Sci, 22(9), pp.4557~ (2021)[DOI]
35. Bottens RA, "Cell-penetrating peptides(CPPs)as therapeutic and diagnostic agents for cancer", Cancers(Basel), 14(22), pp.5546~ (2022)[DOI]

관련 논문AI추천