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Cyclin-dependent Kinase 저해 단백질 p16INK4A의 인체 암세포에서의 세포사멸 유도 활성

A Cyclin-Dependent Kinase Inhibitor, p16INK4A, Induces Apoptosis in The Human Cancer Cells.

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참고문헌 (25)

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  8. ". Down-regulation of bcl-2 is associated with p16INK4A-mediated apoptosis in non-small cell lung cancer cells.", 19, pp.1580~1595 (2000)
  9. ". . Induction of apoptosis in p16INK4A mutant cell line by adenovirus-mediated overexpression of p16INK4A protein.", 7, pp.706~711 (2000)
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  11. "and T. Jacks. 1993. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362", pp.847~852
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  13. "Tumor suppressor genes", 10, pp.81~93
  14. "Induced expression of p16 inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complex. Mol. Cell. Biol. 19", 19, pp.1981-~1989
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  17. "The p16INK4a", CDKN2A tumor suppressor and its relatives, pp.1378, F115-~117[DOI]
  18. "Molecular Cloning^A Laboratory manual^Cold Spring Harbor^New York", pp.pp 16.47-~16.57. (2001), 3th ed. CSHL Press
  19. "M. 1991. The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines. Proc. Natl. Acad. Sci. USA 88", pp.5523~5527
  20. "and D. Beach. 1993. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D", CDK4. Nature 366, 704~707
  21. "The INK4a", ARF locus and its two gene products, 1999, pp.9, 22~30[DOI]
  22. "A frequent target for genetic abnormalities in lung cancer. Science 246", pp.491~494
  23. "and. Stability and Folding of the Tumor Suppressor Protein p16.", 285, pp.1869-~1886
  24. "The molecular biology of apoptosis.", 93, pp.2239~2244 (1996)
  25. "Cell-cycle inhibitorsthree families united by a common cause.", 247, pp.1~15

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