본문 바로가기
KERD
논문KCI 등재

Endoscopic Hemostasis for Bleeding Gastric Ulcer Caused by Ibuprofen in a 16-month-old Infant

나소영
대한소아소화기영양학회 (The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition)|2012.06|Pediatric Gastroenterology, Hepatology & Nutrition|제15권 제2호|pp. 105-110|DOI http://dx.doi.org/

1

조회

0

다운로드

0

인용

0

참고문헌

키워드

ChildrenIbuprofenNSAIDsBleeding ulcerEndoscopic hemostasis
주제분류소아과학

초록

Gastric ulcers are rare in children and are typically seen in cases of Helicobacter pylori (H. pylori) infection, non-steroidal anti-inflammatory drugs (NSAIDs) use, and critical illnesses such as sepsis. The risk of a bleeding ulcer due to use of NSAIDs is dependent on the dose, duration, and the individual NSAIDs, but the bleeding may occur soon after the initiation of NSAID therapy. An experience is described of a 16-month-old infant with a bleeding gastric ulcer after taking the usual dosage of ibuprofen for 3 days. The infant was also successfully treated with endoscopic hemostasis. Even a small amount of ibuprofen may be associated with bleeding gastric ulcers in infant.

Abstract

Gastric ulcers are rare in children and are typically seen in cases of Helicobacter pylori (H. pylori) infection, non-steroidal anti-inflammatory drugs (NSAIDs) use, and critical illnesses such as sepsis. The risk of a bleeding ulcer due to use of NSAIDs is dependent on the dose, duration, and the individual NSAIDs, but the bleeding may occur soon after the initiation of NSAID therapy. An experience is described of a 16-month-old infant with a bleeding gastric ulcer after taking the usual dosage of ibuprofen for 3 days. The infant was also successfully treated with endoscopic hemostasis. Even a small amount of ibuprofen may be associated with bleeding gastric ulcers in infant.

참고문헌 (30)

  1. Sullivan PB, "Peptic ulcer disease in children", Paediatrics and Child Health, 20, pp.462~464 (2010)
  2. Huang JQ, "Role of Helicobacter pylori infection and non-steroidal anti-inflammatory drugs in peptic ulcer disease: a meta-analysis", Lancet, 359, pp.14~22 (2002)
  3. Hernández-Diaz S, "Association between nonsteroidal anti-inflammatory drugs and upper gastrointestinal tract bleeding", perforation. An overview of epidemiologic studies published in the 1990s, 2000, pp.160, 2093~2099
  4. Pérez Gutthann S, "Individual nonsteroidal anti-inflammatory drugs and other risk factors for upper gastrointestinal bleeding and perforation", Epidemiology, 8, pp.18~24 (1997)
  5. Sostres C, "Adverse effects of non-steroidal anti-inflammatory drugs (NSAIDs, aspirin and coxibs) on upper gastrointestinal tract", Best Pract Res Clin Gastroenterol, 24, pp.121~132 (2010)
  6. Langman MJ, "Risks of bleeding peptic ulcer associated with individual non-steroidal anti-inflammatory drugs", Lancet, 343, pp.1075~1078 (1994)
  7. Holster IL, "Update on the endoscopic management of peptic ulcer bleeding", Curr Gastroenterol Rep, 13, pp.525~531 (2011)
  8. Cappell MS, "Therapeutic endoscopy for acute upper gastrointestinal bleeding", Nat Rev Gastroenterol Hepatol, 7, pp.214~229 (2010)
  9. Brown K, "The incidence of peptic ulcer bleeding in the US pediatric population", J Pediatr Gastroenterol Nutr, 54, pp.733~736 (2012)
  10. Van Leerdam ME, "Epidemiology of acute upper gastrointestinal bleeding", Best Practice Res Clin Gastroenterol, 22, pp.209~224 (2008)
  11. Park JH, "Medical treatment of peptic ulcer disease in children: role of H2RA, PPI", Pediatr Gastroenterol Hepatol Nutr, 10(1), pp.43~52 (2007)
  12. Ramsoekh D, "Outcome of peptic ulcer bleeding, nonsteroidal anti- inflammatory drug use and Helicobacter pylori infection", Clin Gastroenterol Hepatol, 3, pp.859~864 (2005)
  13. Henry D, "Variability in risk of gastrointestinal complications with individual non-steroidal anti-inflammatory drugs: results of a collaborative meta-analysis", BMJ, 312, pp.1563~1566 (1996)
  14. Lanas A, "Risk of upper gastrointestinal ulcer bleeding associated with selective COX-2 inhibitors, traditional non-aspirin NSAIDs, aspirin, and combinations", Gut, 55, pp.1731~1738 (2006)
  15. Griffin MR, "Nonsteroidal anti-inflammatory drug use and increased risk for peptic ulcer disease in elderly persons", Ann Intern Med, 114, pp.257~263 (1991)
  16. Hunt RH, "Myths and facts in the use of antiinflammatory drugs", Ann Med, 41, pp.423~437 (2009)
  17. O'Laughlin JC, "Effect of aspirin on the human stomach in normals: endoscopic comparison of damage produced one hour, 24 hours, and 2 weeks after administration", Scand J Gastroenterol Suppl, 67, pp.211~214 (1981)
  18. Manguso F, "Helicobacter pylori infection in bleeding peptic ulcer patients after non-steroidal antiinflammatory drug consumption", World J Gastroenterol, 17, pp.4509~4516 (2011)
  19. Huang JQ, "Role of Helicobacter pylori infection and non-steroidal anti-inflammatory drugs in peptic ulcer disease: a meta-analysis", Lancet, 359, pp.14~22 (2002)
  20. Okan A, "Relationship between non-steroidal anti- inflammatory drug use and Helicobacter pylori infection in bleeding or uncomplicated peptic ulcers: A case-control study", J Gastroenterol Hepatol, 18, pp.18~25 (2003)
  21. Baxter M, "Dieulafoy's lesion: current trends in diagnosis and management", Ann R Coll Surg Engl, 92, pp.548~554 (2010)
  22. Chaer R, "Dieulafoy’s disease", Am Coll Surg, 196, pp.290~296 (2003)
  23. Lee YT, "Dieulafoy’s lesion", Gastrointest Endosc, 58, pp.236~243 (2003)
  24. Senger JL, "The evolution of Dieulafoy's lesion since 1897: then and now-a journey through the lens of a pediatric lesion with literature review", Gastroenterol Res Pract 2012, pp.432517~ (2012)
  25. Kay MH, "Therapeutic endoscopy for nonvariceal gastrointestinal bleeding", J Pediatr Gastroenterol Nutr, 45, pp.157~171 (2007)
  26. Aabakken L, "Current endoscopic and pharmacological therapy of peptic ulcer bleeding", Best Pract Res Clin Gastroenterol, 22, pp.243~259 (2008)
  27. Fyock CJ, "Colonoscopic polypectomy and associated techniques", World J Gastroenterol, 16, pp.3630~3637 (2010)
  28. Morris ML, "Electrosurgery in gastrointestinal endoscopy: principles to practice", Am J Gastroenterol, 104, pp.1563~1574 (2009)
  29. Chiu PW, "Acute nonvariceal upper gastrointestinal bleeding", Curr Opin Gastroenterol, 26, pp.425~428 (2010)
  30. 정일권, "출혈 소화성궤양 치료의 가이드라인", 대한소화기학회지, 54(5), pp.298~308 (2009), 대한소화기학회

관련 논문AI추천

A Case of Small Bowel Ulcer Associated with Helicobacter pylori이정원, 이지현, Eun Young Kim, Jee Hyun Lee, Kon Hee Lee, Saet Byul Woo, Su Rin Shin대한소아소화기영양학회 · Pediatric Gastroenterology, Hepatology & Nutrition2012 · 제15권 제4호Clinical and Endoscopic Findings in Children with Peptic Ulcer in Terms of Helicobacter pylori in Incheon차한, Eell Ryoo, Ka Yeong Chun, Sang Hee Cho, Yeun Sun Kim대한소아소화기영양학회 · Pediatric Gastroenterology, Hepatology & Nutrition2012 · 제15권 제1호진통소염제에 의한 위 십이지장 궤양에 합병된 위 출구 폐쇄 1예백소야, 변성환, 장수희, 최창환대한소아소화기영양학회 · Pediatric Gastroenterology, Hepatology & Nutrition2005 · 제8권 제2호Ibuprofen 사용 후 위궤양을 합병한 유문동 격막 1예정지, 문경래대한소아소화기영양학회 · Pediatric Gastroenterology, Hepatology & Nutrition2010 · 제13권 제1호Usefulness of Ultrasonography in the Diagnosis of Peptic UlcerDisease in ChildrenEun Joo Lee, Jae Hong Park, Yeoun Joo Lee대한소아소화기영양학회 · Pediatric Gastroenterology, Hepatology & Nutrition2019 · 제22권 제1호A case of gastroduodenal ulcer complicating Kawasaki disease고홍, 김승, 김경민, 손한별대한소아응급의학회 · 대한소아응급의학회지2019 · 제6권 제2호

이 간행물의 다른 논문 (9건)

Benign Recurrent Intrahepatic Cholestasis with a Single Heterozygote Mutation in the ATP8B1 GeneYoo Min Lee, 최연호, 김미진, Chang Seok Ki, Yun Seok Lee, Yoon Leepp. 22-126Strategy to Overcome Drug Resistance That Develops during Treatment of Chronic Hepatitis B in ChildrenSuk Jin Hong, Byung-Ho Choepp. 63-73The Role of Inflammatory Mediators in the Pathogenesis of Nonalcoholic Fatty Liver Disease김준성pp. 74-78How to Manage the Pediatric Nutritional Support Team: Updates양혜란pp. 79-84Comparison of Four Commercial ELISA Kits and In-House Immunoblotting for Diagnosis of Helicobacter pylori Infection우향옥, 고경혁, 이우곤, Ji Sook Park, Hoar Lim Jeong, Yang‐Sook Jung, 전진수, 이광호, 서지현, 조명제, 윤희상, 임재영, 염정숙, 박찬후, 백승철pp. 85-90
원문 보기