Clinical Study of Congenital Esophageal Stenosis: Comparison according to Association of Esophageal Atresia and Tracheoesophageal Fistula
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Purpose: Congenital esophageal atresia (CES) is a rare congenital disease. The severity of symptoms is variable; thus, diagnosis is difficult and tends to be delayed. CES is frequently accompanied by esophageal atresia (EA) with/without tracheoesophageal fistula (TEF). We investigated the characteristics of CES by reviewing our experi-ence with CES patients and researched the differences between CES with EA-TEF and isolated CES. Methods: A total of 31 patients underwent operations for CES were reviewed retrospectively. The patients were div-ided into two groups according to the association with EA-TEF, and compared the differences. Results: Sixteen boys and 15 girls were included. The mean age at symptom onset was 8 months old, and the mean age at diagnosis was 21 months old. Nine patients with EA-TEF were included group A, whereas the other 22 patients were assigned to group B. There were no differences in sex, gestational age, associated anomalies and pathologic results between the groups. In group A, the age at diagnosis and age at surgery were younger than in group B despite the age at symptom occurrence being similar. Postoperative complications occurred only in group A. Conclusion: In this study, symptoms occurred during the weaning period, and vomiting was the most frequent symptom. CES patients with EA-TEF tended to be diagnosed and treated earlier despite the age at symptom occur-rence being similar. CES patients with EA-TEF had more postoperative complications; therefore, greater attention should be paid during the postoperative period.
Abstract
Purpose: Congenital esophageal atresia (CES) is a rare congenital disease. The severity of symptoms is variable; thus, diagnosis is difficult and tends to be delayed. CES is frequently accompanied by esophageal atresia (EA) with/without tracheoesophageal fistula (TEF). We investigated the characteristics of CES by reviewing our experi-ence with CES patients and researched the differences between CES with EA-TEF and isolated CES. Methods: A total of 31 patients underwent operations for CES were reviewed retrospectively. The patients were div-ided into two groups according to the association with EA-TEF, and compared the differences. Results: Sixteen boys and 15 girls were included. The mean age at symptom onset was 8 months old, and the mean age at diagnosis was 21 months old. Nine patients with EA-TEF were included group A, whereas the other 22 patients were assigned to group B. There were no differences in sex, gestational age, associated anomalies and pathologic results between the groups. In group A, the age at diagnosis and age at surgery were younger than in group B despite the age at symptom occurrence being similar. Postoperative complications occurred only in group A. Conclusion: In this study, symptoms occurred during the weaning period, and vomiting was the most frequent symptom. CES patients with EA-TEF tended to be diagnosed and treated earlier despite the age at symptom occur-rence being similar. CES patients with EA-TEF had more postoperative complications; therefore, greater attention should be paid during the postoperative period.
참고문헌 (21)
- Neilson IR, "Distal congenital esophageal stenosis associated with esophageal atresia", J Pediatr Surg, 26, pp.478~481 (1991)
- 남소현, "선천성 식도 협착증의 진단 및 치료", 대한외과학회지, 76(6), pp.383~387 (2009), 대한외과학회
- 이건송, "Preoperative Diagnosis of Congenital Esophageal Stenosis Caused by Tracheobronchial Remnants Using Miniprobe Endoscopic Ultrasonography in a Child", Pediatric Gastroenterology, Hepatology & Nutrition, 15(1), pp.52~56 (2012), 대한소아소화기영양학회
- Terui K, "Endoscopic management for congenital esophageal stenosis: a systematic review", World J Gastrointest Endosc, 7, pp.183~191 (2015)
- Nihoul-Fékété C, "Congenital esophageal stenosis", Pediatr Surg Int, 2, pp.86~92 (1987)
- Ramesh JC, "Congenital esophageal stenosis: report of three cases, literature review, and a proposed classification", Pediatr Surg Int, 17, pp.188~192 (2001)
- Takamizawa S, "Congenital esophageal stenosis: therapeutic strategy based on etiology", J Pediatr Surg, 37, pp.197~201 (2002)
- Kawahara H, "Clinical characteristics of congenital esophageal stenosis distal to associated esophageal atresia", Surgery, 129, pp.29~38 (2001)
- Zhao LL, "Congenital esophageal stenosis owing to ectopic tracheobronchial remnants", J Pediatr Surg, 39, pp.1183~1187 (2004)
- Elhalaby EA, "Congenital esophageal stenosis: to dilate or to resect", Ann Pediatr Surg, 2, pp.2~9 (2006)
- Amae S, "Clinical characteristics and management of congenital esophageal stenosis: a report on 14cases", J Pediatr Surg, 38, pp.565~570 (2003)
- Murphy SG, "Isolated congenital esophageal stenosis", J Pediatr Surg, 30, pp.1238~1241 (1995)
- Nishina T, "Congenital esophageal stenosis due to tracheobronchial remnants and its associated anomalies", J Pediatr Surg, 16, pp.190~193 (1981)
- Singaram C, "Peptidergic and nitrinergic denervation in congenital esophageal stenosis", Gastroenterology, 109, pp.275~281 (1995)
- Vasudevan SA, "Management of congenital esophageal stenosis", J Pediatr Surg, 37, pp.1024~1026 (2002)
- Oh CH, "Congenital esophageal stenosis in adults: clinical and radiographic findings in seven patients", AJR Am J Roentgenol, 176, pp.1179~1182 (2001)
- Nemolato S, "Oesophageal tracheobronchial remnants", Gastroenterol Clin Biol, 32, pp.779~781 (2008)
- Romeo E, "Endoscopic management of congenital esophageal stenosis", J Pediatr Surg, 46, pp.838~841 (2011)
- Michaud L, "Characteristics and management of congenital esophageal stenosis: findings from a multicenter study", Orphanet J Rare Dis, 8, pp.186~ (2013)
- Kawahara H, "Esophageal motor function in congenital esophageal stenosis", J Pediatr Surg, 38, pp.1716~1719 (2003)
- Yoo HJ, "Congenital esophageal stenosis associated with esophageal atresia", tracheoesophageal fistula: clinical and radiologic features, 2010, pp.40, 1353~1359