Postoperative Complications of Esophageal Atresia and Role of Endoscopic Balloon Dilatation in Anastomotic Strictures
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Purpose: Esophageal atresia (EA) with or without tracheoesophageal fistula (TEF) is a congenital anomaly that can cause frequent digestive and nutritional problems, even after repair. The most common complication is anastomotic stricture, for which reoperation or balloon dilatation is performed. This study aimed to evaluate the postoperative complications of EA and the role of endoscopic balloon dilatation (EBD) in cases of anastomotic stricture. Methods: We retrospectively analyzed patients diagnosed with EA with or without TEF between January 2000 and February 2021. Patients’ baseline characteristics, associated anomalies, and postoperative complications were reviewed. Results: Among 26 patients, 14 (53.8%) were male, 12 (46.2%) had coexisting anomalies, and the median follow-up was 6.1 years (range, 1.2–15.7 years). In univariate analysis, prematurity, low birth weight, and long-gap EA were associated with postoperative complications in 12 (46.2%) patients. Among the 10 (38.5%) patients with anastomotic stricture, nine (90.0%) required EBD. Regarding the first EBD, it was performed at a median of 3.3 months (range, 1.2–7.6 months) post-repair, while the average patient weight was 4.6 kg. The mean diameter ranged from 3.3 to 9.1 mm without major complications. In univariate analysis, long-gap EA alone was significantly associated with EBD. Conclusion: Approximately half of the patients experienced complications after EA repair. In particular, patients with a long-gap EA had a significantly increased risk of complications, such as anastomotic strictures. EBD can be safely used, even in infants.
Abstract
Purpose: Esophageal atresia (EA) with or without tracheoesophageal fistula (TEF) is a congenital anomaly that can cause frequent digestive and nutritional problems, even after repair. The most common complication is anastomotic stricture, for which reoperation or balloon dilatation is performed. This study aimed to evaluate the postoperative complications of EA and the role of endoscopic balloon dilatation (EBD) in cases of anastomotic stricture. Methods: We retrospectively analyzed patients diagnosed with EA with or without TEF between January 2000 and February 2021. Patients’ baseline characteristics, associated anomalies, and postoperative complications were reviewed. Results: Among 26 patients, 14 (53.8%) were male, 12 (46.2%) had coexisting anomalies, and the median follow-up was 6.1 years (range, 1.2–15.7 years). In univariate analysis, prematurity, low birth weight, and long-gap EA were associated with postoperative complications in 12 (46.2%) patients. Among the 10 (38.5%) patients with anastomotic stricture, nine (90.0%) required EBD. Regarding the first EBD, it was performed at a median of 3.3 months (range, 1.2–7.6 months) post-repair, while the average patient weight was 4.6 kg. The mean diameter ranged from 3.3 to 9.1 mm without major complications. In univariate analysis, long-gap EA alone was significantly associated with EBD. Conclusion: Approximately half of the patients experienced complications after EA repair. In particular, patients with a long-gap EA had a significantly increased risk of complications, such as anastomotic strictures. EBD can be safely used, even in infants.
참고문헌 (22)
- Pinheiro PF, "Current knowledge on esophageal atresia", World J Gastroenterol, 18, pp.3662~3672 (2012)
- Tovar JA, "Current controversies in the surgical treatment of esophageal atresia", Scand J Surg, 100, pp.273~278 (2011)
- Sfeir R, "Esophageal atresia : data from a national cohort", J Pediatr Surg, 48, pp.1664~1669 (2013)
- Mahoney L, "Feeding problems and their underlying mechanisms in the esophageal atresia-tracheoesophageal fistula patient", Front Pediatr, 5, pp.127~ (2017)
- Gottrand M, "Motility, digestive and nutritional problems in esophageal atresia", Paediatr Respir Rev, 19, pp.28~33 (2016)
- Baird R, "Anastomotic stricture after esophageal atresia repair : a critical review of recent literature", Eur J Pediatr Surg, 23, pp.204~213 (2013)
- Campos J, "The burden of esophageal dilatations following repair of esophageal atresia", J Pediatr Surg, 55, pp.2329~2334 (2020)
- Ghiselli A, "Endoscopic dilation in pediatric esophageal strictures: a literature review", Acta Biomed, 89(8-S), pp.27~32 (2018)
- Bairdain S, "Long-gap esophageal atresia is a unique entity within the esophageal atresia defect spectrum", Neonatology, 111, pp.140~144 (2017)
- Friedmacher F, "Postoperative complications and functional outcome after esophageal atresia repair : results from longitudinal single-center follow-up", J Gastrointest Surg, 21, pp.927~935 (2017)
- Dingemann C, "Early complications after esophageal atresia repair : analysis of a German health insurance database covering a population of 8 million", Dis Esophagus, 29, pp.780~786 (2016)
- Eun Young Chang, "Clinical characteristics and treatment of esophageal atresia: a single institutional experience", Annals of Surgical Treatment and Research, 83(1), pp.43~49 (2012), 대한외과학회[DOI]
- Rayyan M, "Neonatal factors predictive for respiratory and gastro-intestinal morbidity after esophageal atresia repair", Pediatr Neonatol, 60, pp.261~269 (2019)
- Ritz LA, "Outcome of patients with esophageal atresia and very low birth weight(≤ 1, 500 g)", Front Pediatr, 8, pp.587285~ (2020)
- Li XW, "A scoring system to predict mortality in infants with esophageal atresia: a case-control study", Medicine (Baltimore), 96, pp.e7755~ (2017)
- Ko D, "Do children with esophageal atresia show worse growth outcomes?", Adv Pediatr Surg, 26, pp.54~60 (2020)
- Koivusalo A, "Location of TEF at the carina as an indicator of long-gap C-type esophageal atresia", Dis Esophagus, 31, pp.doy044~ (2018)
- Shah R, "Predictive factors for complications in children with esophageal atresia and tracheoesophageal fistula", Dis Esophagus, 28, pp.216~223 (2015)
- Rassiwala M, "Determinants of gap length in esophageal atresia with tracheoesophageal fistula and the impact of gap length on outcome", J Indian Assoc Pediatr Surg, 21, pp.126~130 (2016)
- Okata Y, "Evaluation of the intraoperative risk factors for esophageal anastomotic complications after primary repair of esophageal atresia with tracheoesophageal fistula", Pediatr Surg Int, 32, pp.869~873 (2016)
- Tambucci R, "Anastomotic strictures after esophageal atresia repair : incidence, investigations, and management, including treatment of refractory and recurrent strictures", Front Pediatr, 5, pp.120~ (2017)
- Chang CH, "Clinical and nutritional outcome of pediatric esophageal stenosis with endoscopic balloon dilatation", Pediatr Neonatol, 60, pp.141~148 (2019)
