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Whole Genome Sequencing of a Methicillin-Resistant Staphylococcus aureus Sequence Type 5 Strain SA492 Isolated from a Patient in Korean

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초록

Methicillin-resistant Staphylococcus aureus (MRSA) represents antimicrobial-resistant bacteria that can cause a wide range of illnesses both in humans and animals. Multidrug resistance phenotype is common, especially in healthcare-associated (HA) MRSA strains. Currently, one of the most prevalent HA-MRSA clonal lineages in Korean hospitals is sequence type (ST) 5 carrying staphylococcal cassette chromosome mec type II (ST5-SCCmec II). Here, we report the complete genome sequence of an ST5 HA-MRSA strain (SA492) originated from a patient in Korea.

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) represents antimicrobial-resistant bacteria that can cause a wide range of illnesses both in humans and animals. Multidrug resistance phenotype is common, especially in healthcare-associated (HA) MRSA strains. Currently, one of the most prevalent HA-MRSA clonal lineages in Korean hospitals is sequence type (ST) 5 carrying staphylococcal cassette chromosome mec type II (ST5-SCCmec II). Here, we report the complete genome sequence of an ST5 HA-MRSA strain (SA492) originated from a patient in Korea.

참고문헌 (5)

  1. Bartels MD, "Rapid increase of genetically diverse methicillin-resistant Staphylococcus aureus, Copenhagen, Denmark", Emerg. Infect. Dis, 13, pp.1533~1540 (2007)
  2. Kim ES, "A survey of community-associated methicillin-resistant Staphylococcus aureus in Korea", J. Antimicrob. Chemother, 60, pp.1108~1114 (2007)
  3. Peck KR, "Comparison of genotypes and enterotoxin genes between Staphylococcus aureus isolates from blood and nasal colonizers in a Korean hospital", J. Korean Med. Sci, 24, pp.585~591 (2009)
  4. Kang K-M, "Potential role of host defense antimicrobial peptide resistance in increased virulence of health care-associated MRSA strains of sequence type(ST)5versus livestock-associated and community-associated MRSA strains of ST72", Comp. Immunol. Microbiol. Infect. Dis, 62, pp.13~18 (2019)
  5. Park C, "Genomic analysis of heterogeneous vancomycin-intermediate Staphylococcus aureus strains from different clonal lineages in South Korea", Microb. Drug Resist, 27, pp.1271~1281 (2021)

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