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수입산 관상 금붕어(Carassius auratus)의 CyHV-2 감염 증례

A Case report of Cyprinid Herpesvirus 2(CyHV-2) in Imported Ornamental Goldfish Carassius auratus

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In this study, imported ornamental goldfish (Oranda and black moor) with high mortality was investigated with histopathological analysis. Fishes showed clinical symptoms characterized by gill necrosis and cumulative mortality ranging from 60% to 90% within a month after import from Thailand and China in 2021. CyHV-2 was detected in gill, kidney, spleen and liver of goldfishes. Histopathological analysis revealed epithelial necrosis, intranuclear inclusion bodies associated with viral symptoms in epithelial cell, macrophage infiltration and vacuolation in secondary lamella. In addition, disseminated granuloma formation was observed in various organs such as kidney, heart and mesenchymal membranes. These lesions refer to coinfections with CyHV-2 and other pathogens that cause chronic inflammation, which leads to mortality. Therefore, early disease monitoring needs to reduce the mortality when ornamental goldfish is imported.

Abstract

In this study, imported ornamental goldfish (Oranda and black moor) with high mortality was investigated with histopathological analysis. Fishes showed clinical symptoms characterized by gill necrosis and cumulative mortality ranging from 60% to 90% within a month after import from Thailand and China in 2021. CyHV-2 was detected in gill, kidney, spleen and liver of goldfishes. Histopathological analysis revealed epithelial necrosis, intranuclear inclusion bodies associated with viral symptoms in epithelial cell, macrophage infiltration and vacuolation in secondary lamella. In addition, disseminated granuloma formation was observed in various organs such as kidney, heart and mesenchymal membranes. These lesions refer to coinfections with CyHV-2 and other pathogens that cause chronic inflammation, which leads to mortality. Therefore, early disease monitoring needs to reduce the mortality when ornamental goldfish is imported.

참고문헌 (67)

  1. Adamek, M., "CyHV-2 transmission in trad- ed goldfish stocks in Germany-A case study", Journal of Fish Diseases, 41(2), pp.401~404 (2018)
  2. Belema, M., "Handling and packaging of ornamental fishes for successful transportation", International Journal of Fisheries and Aquatic Studies, 5(5), pp.263~265 (2017)
  3. Bercovier, H., "Cloning of the koi herpesvirus(KHV)gene encoding thymidine kinase and its use for a highly sensitive PCR based diagnosis", BMC microbiology, 5(1), pp.1~9 (2005)
  4. Bernoth, E. M., "Viral diseases of aquarium fish", Seminars in Avian and Exotic Pet Medi-cine, 4(2), pp.103~110 (1995)
  5. Boitard, P. M., "First detection of cyprinid herpesvirus 2(CyHV-2)in goldfish(Carassius aur-atus)in France", Journal of Fish Diseases, 39(6), pp.673~680 (2016)
  6. Chai, W., "Evaluation of Cyprinid herpesvirus 2latency and reactivation in Carassius gibel", Microor-ganisms, 8(3), pp.445~ (2020)
  7. Chauhan, R., "Pathogenic effects of three species of fungi(Aphanomyces laevis, Aspergillus niger and Saprolegnia parasitica)on goldfish(Carrasius auratus L.)", Indo Global J. Phar-maceut. Sci, 4(2), pp.41~46 (2014)
  8. Cole, B.E., "Shipping practices in the ornamental fish industry" (1999)
  9. Colquhoun, D. J., "Francisella infections in farmed and wild aquatic organisms", Veterinary re-search, 42(1), pp.1~15 (2011)
  10. Daněk, T., "Massive mortality of Prussian carp Carassius gibelio in the upper Elbe basin associated with herpesviral hematopoietic necrosis(CyHV-2)", Diseases of Aquatic Organisms, 102(2), pp.87~95 (2012)
  11. Davison, A. J., "Comparative genomics of carp herpesviruses", Journal of Virology, 87(5), pp.2908~2922 (2013)
  12. Doszpoly, A., "Introduction of the family Alloher-pesviridae : the first molecular detection of herpesviruses of cyprinid fish in Hungary", Magyar Allatorvo-sok Lapja, 133(3), pp.174~181 (2011)
  13. Dykova, I., "Amoebic infections in goldfishes and granulomatous lesions", Folia Parasitologica, 43(2), pp.81~90 (1996)
  14. Dymowska, A. K., "Structure and function of ionocytes in the freshwater fish gill", Respiratory physiology & neurobiology, 184(3), pp.282~292 (2012)
  15. Fichi, G., "Detection of cyprinid herpesvirus 2 in as- sociation with an Aeromonas sobria infection of Carassius carassius (L.), in Italy", Journal of Fish Diseases, 36(10), pp.823~830 (2013)
  16. "Statistics of fishery production" (2021)[URL]
  17. Foscarini, R., "Induction and development of bacterial gill disease in the eel(Anguilla japonica)experi-mentally infected with Flexibacter columnaris : pathological changes in the gill vascular structure and in cardiac performance", Aquaculture, 78(1), pp.1~20 (1989)
  18. Gómez, S., "Fish mycobacteriosis : morphopathological and immunocytochemical aspects", Journal of Fish Diseases, 16(2), pp.137~141 (1993)
  19. Goodwin, A. E., "Herpesviral haematopoietic necrosis virus(CyHV-2)infection : case studies from commercial goldfish farms", Journal of Fish Diseases, 32(3), pp.271~278 (2009)
  20. Groff, J. M., "A viral epizootic in cultured populations of juvenile goldfish due to a putative herpesvirus etiology", Journal of Veterinary Diagnostic Investigation, 10(4), pp.375~378 (1998)
  21. Haenen, O., "Neglected viral diseases in freshwater fish farming", Bulletin of the European Association of Fish Pathologists, 38(3), pp.105~115 (2018)
  22. Hanson, L., "Herpesviruses that infect fish", Viruses, 3(11), pp.2160~2191 (2011)
  23. Hedrick, R. P., "Sus-ceptibility of koi carp, common carp, goldfish, and goldfish× common carp hybrids to cyprinid herpes-virus-2 and herpesvirus-3", Journal of Aquatic Animal Health, 18(1), pp.26~34 (2006)
  24. Hemalatha, S., "Histopathological anal-ysis of sublethal toxicity of zinc chloride to the res-piratory organs of the airbreathing catfish Heterop-neustes fossilis(Bloch)", Biological Research, 30, pp.11~22 (1997)
  25. Hine, P. M., "Cyprinid her-pesvirus 2 in New Zealand goldfish", Surveillance, 33(4), pp.3~5 (2006)
  26. Hughes, G. M., "The structure of fish gills in relation to their respiratory function", Biological reviews, 48(3), pp.419~475 (1973)
  27. Huh, M. D., "Review : The histological structure and the pathological lesions of gill in teleosts", Journal of fish pathology, 6(1), pp.65~70 (1993)
  28. Ito, T., "Importation of CyHV-2 infected goldfish into the Netherlands", Diseases of Aquatic Organisms, 126(1), pp.51~62 (2017)
  29. Jeffery, K. R., "Isolation of a cyprinid herpesvirus 2from goldfish, Carassius auratus (L.), in the UK", Journal of Fish Diseases, 30(11), pp.649~656 (2007)
  30. Jiang, N., "Diagnostic case report : Disease outbreak induced by CyHV-2 in goldfish in China", Aquaculture, 523, pp.735156~ (2020)
  31. Jung, S. J., "Herpesviral haematopoietic necrosis of goldfish, Carassius auratus(L.)", Journal of fish diseases, 18(3), pp.211~220 (1995)
  32. 정명화, "Detection of herpesviral hematopoietic necrosis virus (Cyprinid herpesvirus 2, CyHV-2) from goldfish, Carassius auratus (L.) in Korea", Fisheries and Aquatic Sciences, 25(7), pp.403~408 (2022), 한국수산과학회[DOI]
  33. Kerstetter, T. H., "On the mechanisms of sodium ion transport by the irri- gated gills of rainbow trout (Salmo gairdneri).", The Journal of General Physiology, 56(3), pp.342~359 (1970)
  34. 김대영, "관상어 시장규모 및 인식도 분석을 통한 관상어산업의 개선과제", 수산경영론집, 43(3), pp.89~106 (2012), 한국수산경영학회
  35. 김대영, "우리나라 관상어산업의 발전방향에 관한 연구", 수산해양교육연구, 23(4), pp.626~641 (2011), 한국수산해양교육학회
  36. Kotob, M. H., "The impact of co-infections on fish : a review", Veterinary research, 47(1), pp.1~12 (2017)
  37. Kwon, S. R., "Monitoring of carp edema virus disease and herpesviral hematopoietic necrosis in Cyprinus car-pio and Carassius auratus imported from China", Journal of fish pathology, 33(1), pp.1~6 (2020)
  38. Lauren, D.J., "Fish gill. A sensitive target for waterborne pollutants", ASTM Special Technical Publication, (1124), pp.223~244 (1991)
  39. Lu, J., "Hematological and histological changes in Prussian Carp Carassius gibelio infected with Cyprinid Herpesvirus 2", Journal of Aquatic Animal Health, 28(3), pp.150~160 (2016)
  40. Luo, Y. Z., "Haematopoietic necrosis of cultured prussian carp, carassius gibelio(bloch), associated with cyprinid herpesvirus 2", Journal of Fish Diseases, 36(12), pp.1035~1039 (2013)
  41. Lim, L. C., "Recent developments and improvements in ornamental fish pack-aging systems for air transport", Aquaculture Re-search, 34(11), pp.923~935 (2003)
  42. Maina, J. N., "Structure, function and evolution of the gas exchangers : comparative perspectives", Journal of anatomy, 201(4), pp.281~304 (2002)
  43. Mandrioli, L., "Pathological and tissue-based molecular investigation of granulomas in cichlids reared as ornamental fish", Animals, 12(11), pp.1366~ (2022)
  44. Masud, N., "A neglected fish stressor: mechanical disturbance during transportation impacts susceptibility to disease in a globally important ornamental fish", Diseases of Aquatic Organisms, 134(1), pp.25~32 (2019)
  45. Matras, M., "Carp edema virus in Polish aquaculture-evidence of significant sequence divergence and a new lineage in common carp Cyprinus carpio (L.)", Journal of fish diseases, 40(3), pp.319~325 (2017)
  46. Maekawa, S., "Current knowledge of nocardiosis in teleost fish", Journal of fish diseases, 41(3), pp.413~419 (2018)
  47. Mellergaard, S., "Herpesvirus-like particles in angelfish Pterophyllum altum", Diseases of Aquatic Organisms, 5, pp.151~155 (1988)
  48. "Statistics of domestic ornamental fish trade" (2019)[URL]
  49. "제1차 관상어산업육성 5개년 종합계획(2016-2020년)" (2015)[URL]
  50. Monticini, P., "Production and commerce of ornamental fish: technical managerial and legislative aspects", FAO-GLOBEFISH, ~ (2010)
  51. National Fishery Products Quality Management Service, "Imports (exports) quarantine statistics", ~ (2021)
  52. Novotny, L., "Morphology and distribution of granulomatous inflammation in fresh- water ornamental fish infected with mycobacteria", Journal of Fish Diseases, 33(12), pp.947~955 (2010)
  53. Öztürk, T., "Ichthyophonus hoferi infection in goldfish (Cara- ssius auratus)", Journal of Fisheries Sciences. com, 4(4), pp.304~309 (2010)
  54. Rahmati-Holasoo, H., "Detection of carp pox virus (CyHV-1) from koi (Cyprinus carpio L.) in Iran;clinico-pathological and molecular characterization", Molecular and cellular probes, 54, pp.101668~ (2020)
  55. Ren, W., "Investigation of Cyprinid herpesvirus 2 and bacterial coinfection in Carassius gibel", Aquaculture, 537, pp.736521~ (2021)
  56. Sahoo, P. K., "Detection of goldfish haematopoietic necrosis herpes virus(Cyprinid herpesvirus-2)with multi-drug resistant Aeromonas hydrophila infection in goldfish : First evidence of any viral disease outbreak in ornamental freshwater aquaculture farms in India", Acta tropica, 161, pp.8~17 (2016)
  57. 송해덕, "국내 양식 금붕어(Carassius auratus)와 수입 진주린(Carassius auratus)에서 Cyprinid Herpesvirus 2 (CyHV-2)의 검출", 한국수산과학회지, 51(4), pp.383~388 (2018), 한국수산과학회[DOI]
  58. Stephens, F. J., "Haematopoietic necrosis in a goldfish(Carassius auratus)associated with an agent morphologically similar to herpesvirus", Australian Veterinary Journal, 82(3), pp.167~169 (2004)
  59. Stevens, C. H., "Stress and welfare in ornamental fishes : what can be learned from aquaculture?", Journal of fish biol-ogy, 91(2), pp.409~428 (2017)
  60. Stone, D. M., "Nucleotide sequence analysis of the glycoprotein gene of putative spring viraemia of carp virus and pike fry rhabdovirus isolates reveals four genogroups", Diseases of Aquatic Organisms, 53(3), pp.203~210 (2003)
  61. Thangaraj, R. S., "Cyprinid herpesvirus-2(CyHV-2) : a comprehensive review", Reviews in Aquaculture, 13(2), pp.796~821 (2021)
  62. Waltzek, T. B., "Development of a polymerase chain reaction assay to detect cyprinid herpesvirus 2 in goldfish", Journal of Aquatic Animal Health, 21(1), pp.60~67 (2009)
  63. Virgin, H. W., "Redefining chronic viral infection", Cell, 138(1), pp.30~50 (2009)
  64. Voelker, F. A., "Amebiasis in goldfish", Veteri-nary Pathology, 14(3), pp.247~255 (1977)
  65. Wei, C., "Persistence of cyprinid herpesvirus 2in asymptomatic goldfish Carassius auratus (L.) that survived an experimental infection", Journal of Fish Diseases, 42(6), pp.913~921 (2019)
  66. Wu T, "The histo- and ultra-pathological studies on a fatal dis- ease of Prussian carp (Carassius gibelio) in mainland China associated with cyprinid herpesvirus 2(CyHV-2)", Aquaculture, 4, pp.8~13 (2013)[DOI]
  67. Yanong, R. P., "Fungal diseases of fish", Veterinary Clinics:Exotic Animal Practice, 6(2), pp.377~400 (2003)

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