공황장애의 발병연령에 따른 정신과적 공존질환의 차이
Difference in psychiatric comorbidity of panic disorder according to age of onset
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Objectives : It is reported that panic disorder is frequently comorbid with other psychiatric illnesses. The aim of this study was to investigate differences of psychiatric comorbidity according to age of onset of panic disorder. Methods : Three hundred-two patients participated in the study. All the patients were evaluated with clinical instrument for the assessment the presence of comorbid other psychiatric disorders and various clinical features; Korean version of Mini International Neuropsychiatric Interview, Self-report questionnaires (Beck Anxiety Inventory, Beck Depression Inventory, Anxiety Sensitivity Index and State-Trait Anxiety Inventory) and clinical rating scale (Hamilton Anxiety Scale, Hamilton Depression Scale and Global Assessment of Functional score). Chi-Square test was used to determine the difference between early onset and late onset panic disorder Results : Forty percent of panic patients were found to at least one comorbid psychiatric diagnosis. There were no differences among the groups divided by number of comorbidity in sex, agoraphobia comorbidity, duration of panic disorder, except onset age of panic disorder. Early onset group have more comorbidy with social phobia, agoraphobia, PTSD. We also found that Early onset panic disorder patients were more likely to experience derealization, nausea, parethesia than late onset panic disorder patients. Conclusion : The results of our study are in keeping with previous data from other parts of the world. Our finding suggest that earier onset of panic disorder related to more psychiatric comorbidity.
Abstract
Objectives : It is reported that panic disorder is frequently comorbid with other psychiatric illnesses. The aim of this study was to investigate differences of psychiatric comorbidity according to age of onset of panic disorder. Methods : Three hundred-two patients participated in the study. All the patients were evaluated with clinical instrument for the assessment the presence of comorbid other psychiatric disorders and various clinical features; Korean version of Mini International Neuropsychiatric Interview, Self-report questionnaires (Beck Anxiety Inventory, Beck Depression Inventory, Anxiety Sensitivity Index and State-Trait Anxiety Inventory) and clinical rating scale (Hamilton Anxiety Scale, Hamilton Depression Scale and Global Assessment of Functional score). Chi-Square test was used to determine the difference between early onset and late onset panic disorder Results : Forty percent of panic patients were found to at least one comorbid psychiatric diagnosis. There were no differences among the groups divided by number of comorbidity in sex, agoraphobia comorbidity, duration of panic disorder, except onset age of panic disorder. Early onset group have more comorbidy with social phobia, agoraphobia, PTSD. We also found that Early onset panic disorder patients were more likely to experience derealization, nausea, parethesia than late onset panic disorder patients. Conclusion : The results of our study are in keeping with previous data from other parts of the world. Our finding suggest that earier onset of panic disorder related to more psychiatric comorbidity.
참고문헌 (32)
- David A. Katerndahl, "Lifetime prevalence of Panic states", Am J Psychiatry, 15, pp.246~249 (1993)
- Brown TA, "Diagnostic comorbidity in panic disorder: effect on treatment outcome and course of comorbid diagnoses following treatment", J of Consult Clin Psychol, 63, pp.408~418 (1995)
- Kessler RC, "Lifetime panic depression comorbidity in national comorbidity Survey", Arch Gen Psychiatry, 55, pp.801~808 (1998)
- Noyes R, "Reduction in hypochondriasis with treatment of panic disorder", Br J Psychiatry, 149, pp.631~635 (1986)
- Cox BJ, "Substance abuse and panic related anxiety: a critical review", Behav Res Ther, 28, pp.385~393 (1990)
- Toshiya Iketani, "Personality disorder comorbidity in panic disorder patients with or without current major depression", Depression and Anxiety, 15, pp.176~182 (2002)
- Scheibe G, "Predictors and outcome in panic disorder: a 2-year prospective follow-up study", Psychopathology, 30, pp.177~184 (1997)
- William J. Apfeldorf, "Morbidity of comorbid psychiatric diagnoses in the clinical presentation of panic disorder", Depression and Anxiety, 12, pp.78~84 (2000)
- Segui J, "Salvador-Carulla L, Ortiz M. Differential clinical features of early-onset panic disorder", J Affect Disord, 54, pp.109~117 (1999)
- Bermanzohn P.C., "Hierarchical diagnosis in chronic schizophrenia: a clinical study of co-occurring syndromes", Schizophrenia Bulletin, 26, pp.517~525 (2000)
- Cosoff S.J., "The prevalence of comorbid anxiety in schizophrenia. schizoaffective disorder and bipolar disorder", Australian and New Zealand Journal of Psychiatry, 32, pp.67~72 (1998)
- Toshiya Iketani, "Patterns of axis Ⅱ comorbidity in early-onset versus late-onset panic disorder in Japan", Comprehensive Psychiatry, 45, pp.114~120 (2004)
- Sheehan DV, "The Mini-interational Neuropsychiatric Interview(M.I.N.I): the development and validation of structured diagnostic psychiatric interview for DSM-Ⅳ and ICD-10", J Clin Psychiatry, 59(20), pp.2~33 (1998)
- Sang Wo You, "The Mini-interational Neuropsychiatric Interview Anxiety and mood", 5~55 (2006)
- Sara Venturello, "Premorbid Conditions and precipitating events in early-onset panic disorder", Comprehensive Psychiatry, 43, pp.28~36 (2002)
- Renee D. Goodwin, "Generalizability and correlates of clinically derived panic subtypes in the population", Depression and Anxiety, 15, pp.69~74 (2002)
- Reed V, "DSM-IV panic attacks and panic disorder in a community sample of adolescents and young adults: how specific are panic attacks?", J Psychiatr Res, 32(6), pp.335~345 (1998)
- Sheehan DV, "Age of onset of phobic disorders: a reevaluation", Compr Psychiatry, 22, pp.544~553 (1981)
- Goodwin, R., "Obsessive compulsive disorder and separation anxiety comorbidity in early onset panic disorder", Psychological Medicine, 31, pp.1307~1310 (2001)
- Starcevic V, "Patterns of comorbidity in panic disorder and agoraphobia", Psychiatry Res, 42, pp.171~ (1992)
- Eaton WW, "Panic and phobia: the diagnosis of panic disorder and phobic disorder, in Psychiatric Disorder in America", pp.155~203 (1991), Free Press
- Kessler RC, "Lifetime and 12-month prevalence of DSM-Ⅲ-R psychiatric disorders in the United States: results from the National comorbidity Survey", Arch Gen Psychiatry, 51, pp.8~19 (1994)
- Kimberly A. Yonkers, "Is the course of panic disorder the same in women and men?", Am J Psychiatry, 155, pp.596~602 (1998)
- Cox BJ, "Gender effects and alcohol use in panic disorder with agoraphobia", Behav Res Ther, 31, pp.413~416 (1993)
- Wittchen, H.-U., "Differential clinical features of early-onset panic disorder", J Affect Disord, 54, pp.109~117 (1999)
- Goldstein, R., "Familial aggregation and phenomenology of early onset (at or before age 20 years) panic disorder", Archives of General Psychiatry, 54, pp.271~278 (1997)
- Battaglia M, "Anticipation of age at onset in panic disorder", Am J Psychiatry, 155, pp.590~595 (1998)
- Cassno GB, "A clinical evaluation on 150 patients with panic disorder", agoraphobia, 1989, pp.30, 5~12
- Toni C, "Psychosensorial and related phenomena in panic disorder and in temporal lobe epilepsy", Compr Psychiatry, 37, pp.125~133 (1996)
- Bovasso G, "Types of panic attacks and their association with psychiatric disorder and physical illness", Compr Psychiatry, 40(6), pp.469~477 (1999)
- Weissman, M.M., "Suicidal ideation and suicide attempts in panic disorder and attacks", N. Engl. J. Med., 321, pp.1209~1214 (1989)
- Katerndahl DA, "A comparison of persons with early- vs. late-onset panic attacks", J Clin Psychiatry, 61, pp.422~427 (2000)