공황장애 호흡기 아형과 비호흡기 아형의 임상 특성 비교
Comparison of clinical characteristics between respiratory and non-respiratory subtypes of panic disorder
1
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
Objectives: The goal of this study was to compare the clinical characteristics of panic disorder respiratory subtype (PD-R) and non-respiratory subtype (PD-NR). Methods: 84 patients with panic disorder were enrolled and divided into 2 groups, 29 PD-R and 55 PD-NR. Diagnosis of panic disorder was evaluated using Diagnostic and Statistical Manual of Mental Disorders 4th edition and Mini International Neuropsychiatric Interview. They were also measured with Hamilton Rating Scale for Anxiety (HAM-A), Hamilton Rating Scale for Depression (HAM-D), and Panic Disorder Severity Scale (PDSS). Results: PD-R group showed significantly higher scores in PDSS than those of PD-NR group(p=.027). After controlling the severity of panic disorder and gender, PD-R group showed higher HAM-D and somatic anxiety subscale of HAM-A than those of PD-NR group. Furthermore, results of logistic regression analysis suggested that the somatic anxiety was possible risk factor of PD-R (OR=1.404,p=0.009). Conclusion: These results suggest that somatic anxiety and depressive symptom would be important clinical characteristics of PD-R.
Abstract
Objectives: The goal of this study was to compare the clinical characteristics of panic disorder respiratory subtype (PD-R) and non-respiratory subtype (PD-NR). Methods: 84 patients with panic disorder were enrolled and divided into 2 groups, 29 PD-R and 55 PD-NR. Diagnosis of panic disorder was evaluated using Diagnostic and Statistical Manual of Mental Disorders 4th edition and Mini International Neuropsychiatric Interview. They were also measured with Hamilton Rating Scale for Anxiety (HAM-A), Hamilton Rating Scale for Depression (HAM-D), and Panic Disorder Severity Scale (PDSS). Results: PD-R group showed significantly higher scores in PDSS than those of PD-NR group(p=.027). After controlling the severity of panic disorder and gender, PD-R group showed higher HAM-D and somatic anxiety subscale of HAM-A than those of PD-NR group. Furthermore, results of logistic regression analysis suggested that the somatic anxiety was possible risk factor of PD-R (OR=1.404,p=0.009). Conclusion: These results suggest that somatic anxiety and depressive symptom would be important clinical characteristics of PD-R.
참고문헌 (34)
- American Psychiatric Association, "Diagnostic and Statistical Manual of mental Disorders. 4th ed" (1994), Americal Psychiatric Press
- Bass C., "Hyperventilation and its relationship to anxiety and panic", Integrative Psychiatry, (5), pp.274~291 (1987)
- Aronson TA, "Phenomenology of panic attacks: a descriptive study of panic disorder patients' self-reports", J Clin Psychiatry, 49(1), pp.8~13 (1988)
- Gorman JM, "Neuroanatomical hypothesis of panic disorder, revised", Am J Psychiatry, 157(4), pp.493~505 (2000)
- Klein DF, "False suffocation alarms, spontaneous panics, and related conditions. An integrative hypothesis", Arch Gen Psychiatry, 50(4), pp.306~317 (1993)
- Vickers K, "Respiratory symptoms and panic in the National Comorbidity Survey: a test of Klein's suffocation false alarm theory", Behav Res Ther, 43(8), pp.1011~1018 (2005)
- Goetz RR, "Symptoms essential to the experience of sodium lactate-induced panic", Neuropsychopharmacology, 14(5), pp.355~366 (1996)
- Hegel MT, "Psychophysiological assessment of respiratory function in panic disorder: evidence for a hyperventilation subtype", Psychosom Med, 59(3), pp.224~230 (1997)
- Biber B, "Panic disorder subtypes: differential responses to CO2 challenge", Am J Psychiatry, 156(5), pp.739~744 (1999)
- Abrams K, "Evidence for respiratory and nonrespiratory subtypes in panic disorder", Depress Anxiety, 23(8), pp.474~481 (2006)
- Briggs AC, "Subtyping of panic disorder by symptom profile", Br J Psychiatry, 163, pp.201~209 (1993)
- Meuret AE, "Panic attack symptom dimensions and their relationship to illness characteristics in panic disorder", J Psychiatr Res, 40(6), pp.520~527 (2006)
- Ley R, "Agoraphobia, the panic attack and the hyperventilation syndrome", Behav Res Ther, 23(1), pp.79~81 (1985)
- Bandelow B, "Cardio-respiratory and other symptom clusters in panic disorder", Anxiety, 2(2), pp.99~101 (1996)
- Nardi AE, "Respiratory panic disorder subtype: acute and long-term response to nortriptyline, a noradrenergic tricyclic antidepressant", Psychiatry Res, 120(3), pp.283~293 (2003)
- Telch MJ, "Emotional responding to hyperventilation as a predictor of agoraphobia status among individuals suffering from panic disorder", J Behav Ther Exp Psychiatry, 34(2), pp.161~170 (2003)
- Onur E, "Panic disorder subtypes: further clinical differences", Depress Anxiety, 24(7), pp.479~486 (2007)
- Horwath E, "Weissman MM. Panic disorder with smothering symptoms: evidence for increased risk in first-degree relatives", Depress Anxiety, 6(4), pp.147~153 (1997)
- American Psychiatric Association, "Diagnostic and Statistical Manual of Mental Disorders. 4rd ed", pp.393~443 (1994), American Psychiatric Press
- Sheehan DV, "The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10", Clinical Psychiatry, 59(20), pp.22~33 (1998)
- Nardi AE, "A three-year follow-up study of patients with the respiratory subtype of panic disorder after treatment with clonazepam", Psychiatry Res, 137(1), pp.61~70 (2005)
- Freire RC, "Clinical features of respiratory and nocturnal panic disorder subtypes", Psychiatry Res, 152(2), pp.287~291 (2007)
- 김정범, "공황장애의 평가", 생물치료정신의학, 6(2), pp.248~259 (2000), 대한생물치료정신의학회
- Hamilton M, "The assessment of anxiety state by rating", Br J Med Psychol, 32, pp.50~55 (1959)
- Hamilton M, "A rating scale for depression", J Neurol Neurosurg Psychiat, 23, pp.56~62 (1960)
- Freire RC, "Panic disorder respiratory subtype: a comparison between responses to hyperventilation and CO2 challenge tests", Psychiatry Res, 157(1), pp.307~310
- Noyes R Jr, "Outcome of panic disorder. Relationship to diagnostic subtypes and comorbidity", Arch Gen Psychiatry, 47(9), pp.809~818 (1990)
- Miller HE, "Effect of acute tryptophan depletion on CO2-induced anxiety in patients with panic disorder and normal volunteers", Br J Psychiatry, 176, pp.182~188 (2000)
- Klein DF, "Anxiety reconceptualized", Compr Psychiatry, 21(6), pp.411~427 (1980)
- Russell JL, "Nonfearful panic disorder in neurology patients validated by lactate challenge", Am J Psychiatry, 148(3), pp.361~364 (1991)
- Schmid NB, "Classification of panic attack subtypes in patients and normal controls in response to biological challenge: implications for assessment and treatment", J Anxiety Disord, 16(6), pp.625~638 (2002)
- Buller R, "Chronology of panic and avoidance, age of onset in panic disorder, and prediction of treatment response. A report from the Cross-National Collaborative Panic Study", Eur Arch Psychiatry Clin Neurosci, 240(3), pp.163~168 (1991)
- Goldstein RB, "Familial aggregation and phenomenology of 'early'-onset (at or before age 20 years) panic disorder", Arch Gen Psychiatry, 54(3), pp.271~278 (1997)
- Nardi AE, "Panic disorder and control of breathing", Respir Physiol Neurobiol (2008)
