24주 추적 조사를 통한 한국인 알코올 의존 환자의 재발 예측 인자 규명 연구
A study on relapse predictors in korean alcohol-dependent patients-a 24 weeks follow up study-
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목적: 본 연구에서는 알코올 의존의 재발 예측 인자로 중요하다고 알려진 사회 인구학적 변인, 음주력, 음주갈망, 치료동기, 병식과 같은 요인들 중에 어떤 요인들이 한국인 알코올 의존의 재발을 예측하는지를 전향적으로 조사하였다.방법: 알코올 의존 환자 48명을 대상으로 사회 인구학적 특성, 음주력, Timeline Follow-Back (TLFB), Obsessive-Compulsive Drinking Scale (OCSD), Alcohol Urge Questionnaire (AUQ), Pennsylvania Alcohol Craving Scale (PACS), University of Rhode Island Change Assessment (URICA), Hanil Alcohol Insight Scale (HAIS)등을 조사한 후, 24주간 총 11회에 걸쳐 외래를 방문하도록 하였다. 24주 동안 조사한 TLFB 자료에 근거하여 대상자 중에서 과음(일일 5standard drinking 이상)일이 나타난 경우 혹은 더 이상 추적 방문이 되지 않은 경우 모두 재발한 것으로 하여 재발군으로 분류하였으며, 그렇지 않은 경우를 비재발군으로 분류하였다. 알코올 의존의 재발을 예측할 수 있는 요인을 찾는 방법으로 SPSS PC+11.5 프로그램의 로지스틱 회귀분석을 이용하였다.결과: 음주를 시작한 연령, 음주로 인한 문제가 발생된 연령, 최근 1년간 1일 음주량, 최근 1년간 월 음주일수, PACS, AUQ, OCDS, URICA, HAIS와 같은 요인들 중 최근 1년간 1일 음주량과 HAIS 점수가 알코올 의존의 재발에 영향을 주는 것으로 나타났다. (P<.05).
Abstract
Objectives: The aim of this prospective study is to investigate predictors estimating relapse in Korean alcohol-dependent patients using variables like alcohol history, drinking craving, treatment motivation and insight.Methods: Alcohol dependent patients (N=48) who completed questionnaires about sociodemographic variables and drinking history, Timeline Follow-Back (TLFB), Obsessive-Compulsive Drinking Scale (OCSD), Alcohol Urge Questionnaire (AUQ), Pennsylvania Alcohol Craving Scale (PACS), University of Rhode Island Change Assessment (URICA), Hanil Alcohol Insight Scale (HAIS) were followed-up for 24weeks. Subjects who drank heavily (5 standard drinking or more/day) or didn't followed up anymore were classified as relapse group. We used logistic regression analysis with backward elimination of SPSS PC+11.5 to investigate relapse estimate predictors.Results: Average drinking amount on drinking day for last 1 year and HAIS score were predictors of relapse in alcohol-dependent patients.Conclusion: Our findings suggests that therapist should give more attention to alcohol-dependent patients who had more drinks on drinking day for last 1 year and had lower insight level.
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