본문 바로가기
KERD
논문KCI 등재

경증 외상성 뇌손상 환자에서 신체적 증상, 우울, 불안과 인지기능의 관계

Relations between Somatic Symptoms, Depression, Anxiety, and Cognitive Function in Patients with Mild Traumatic Brain Injury

오상우|노승호|김명헌
대한생물정신의학회 (The Korean Society Of Biological Psychiatry)|2008.08|생물정신의학 (Journal of Korean Society of Biological Psychiatry)|제15권 제3호|pp. 194-203

0

조회

0

다운로드

4

인용

0

참고문헌

주제분류정신과학

초록

Objectives : This study was aimed at evaluating the relationship between somatic symptoms, depression, anxiety, and cognitive function in the patients with Mild Traumatic Brain Injury(MTBI). Methods : Thirty seven patients with MTBI were selected from those patients who had visited the Department of Neuropsychiatry of Wonkwang University Hospital from 2003 to 2007. To assess and quantify the somatic symptoms, depression and anxiety, Personality Assessment Inventory(PAI) was used. Assessment of cognitive function was carried out by using Korean Wechsler Adult Intelligence Scale(K-WAIS), Rey-Kim Memory Test, and Kims Executive Function Test. The effects of somatic symptoms, depression, and anxiety on the cognitive function were evaluated by Pearson correlation test. Results : Somatic symptoms, depression, and anxiety, all showed inverse correlation to cognitive function. Specifically, 1) an increase in somatic symptoms was associated with a decrease in attention, verbal short term memory, verbal recall and recognition, and visual memory. 2) An increase in anxiety was associated with a decrease in verbal recall and recognition. 3) An increase in depression was associated with a decrease in cognitive function that requires high attention and verbal memory. Conclusion : The patients with MTBI display diverse symptoms ranging from cognitive impairment to somatic symptoms, depression, and anxiety. Somatic and emotional symptoms were correlated with cognitive function(especially executive function). Importantly, this study raises the possibility of treating the cognitive impairment associated with MTBI by treating somatic symptoms, depression, and anxiety.

Abstract

Objectives : This study was aimed at evaluating the relationship between somatic symptoms, depression, anxiety, and cognitive function in the patients with Mild Traumatic Brain Injury(MTBI). Methods : Thirty seven patients with MTBI were selected from those patients who had visited the Department of Neuropsychiatry of Wonkwang University Hospital from 2003 to 2007. To assess and quantify the somatic symptoms, depression and anxiety, Personality Assessment Inventory(PAI) was used. Assessment of cognitive function was carried out by using Korean Wechsler Adult Intelligence Scale(K-WAIS), Rey-Kim Memory Test, and Kims Executive Function Test. The effects of somatic symptoms, depression, and anxiety on the cognitive function were evaluated by Pearson correlation test. Results : Somatic symptoms, depression, and anxiety, all showed inverse correlation to cognitive function. Specifically, 1) an increase in somatic symptoms was associated with a decrease in attention, verbal short term memory, verbal recall and recognition, and visual memory. 2) An increase in anxiety was associated with a decrease in verbal recall and recognition. 3) An increase in depression was associated with a decrease in cognitive function that requires high attention and verbal memory. Conclusion : The patients with MTBI display diverse symptoms ranging from cognitive impairment to somatic symptoms, depression, and anxiety. Somatic and emotional symptoms were correlated with cognitive function(especially executive function). Importantly, this study raises the possibility of treating the cognitive impairment associated with MTBI by treating somatic symptoms, depression, and anxiety.

참고문헌 (42)

  1. Kurtzke JF., "Neuroepidemiology", Ann Neurol, 16, pp.265~277 (1984)
  2. Kraus JF., "The incidence of acute brain injury and serious impairment in a defined population", Am J Epidemiol, 119, pp.186~201 (1984)
  3. Sosin DM., "Incidence of mild and moderate brain injury in the United States", Brain Inj, 10, pp.47~54 (1996)
  4. "Korea National Police Agency 2006", ~ (2006)
  5. Korean Occupational Safety & Health agency, "Research on industrial accident" (2005)
  6. Williams DH., "Mild head injury classification", Neurosurgery, 27, pp.422~428 (1990)
  7. Kraus JF., "Epidemiologic aspects of brain injury", Neurol Clin, 14, pp.435~450 (1996)
  8. Binder LM., "A review of mild head trauma", J Clin Exp Neuropsychol, 19, pp.421~431 (1997)
  9. King NS., "Emotional, neuropsychological and organic factors: Their use in the prediction of persisting postconcussion symptoms after moderate and mild head injuries", J Neurol Neurosurg Psychiatry, 61, pp.75~81 (1996)
  10. Leininger BE, "Neuropsychological deficits in symptomatic minor head injury patients after concussion and mild concussion", J Neurol Neurosurg Psychiatry, 53, pp.293~296 (1990)
  11. Rutherford WH., "Postconcussional symptoms: Relationship to acute neurological indices, individual differences, and circumstances of injury. Mild head injury", pp.217~228 (1989), Oxford University Press
  12. Alexander MP., "Mild traumatic brain injury : Pathophysiology, natural history, and clinical management", Neurology, 45, pp.1253~1260 (1995)
  13. Kuhajda MC., "The effect of headache pain on attention (encoding) and memory (recognition)", Pain, 97, pp.213~221 (2002)
  14. Grigsby J., "Chronic pain in associated with deficits in information processing", Percept Mot Skills, 81, pp.403~410 (1995)
  15. Airaksnen E., "Cognitive Functions in depression and anxiety disorders" (2006), Karolinska institutet: Published Report
  16. Boldrini M., "Selective cognitive deficits in obsessive compulsive disorder compared to panic disorder with agoraphobia", Acta Psychiatr Scand, 111, pp.150~158 (2005)
  17. Den Hartog HM., "Cognitive functioning in young and middle-aged unmedicated out-patients with major depression: Testing effort and cognitive speed hypotheses", Psychol Med, 33, pp.1443~1451 (2003)
  18. Fossati P., "Verbal memory performance of patients with a first depressive episode and patients with unipolar and bipolar recurrent depression", J Psychiatr Res, 38, pp.137~144 (2004)
  19. Porter RJ., "Neurocognitive impairment in drug-free major depressive disorder", Br J Psychiatry, 182, pp.214~220 (2003)
  20. Sweeney JA., "Cognitive functioning in depression", J Clin Psychol, 45, pp.836~842 (1989)
  21. Elliott R., "Neuropsychological impairments in unipolar depression: The influence of perceived failure on subsequent performance", Psychol Med, 26, pp.975~989 (1996)
  22. Fossati P., "Executive functioning and verbal memory in young patients with unipolar depression and schizophrenia", Psychiatry Res, 89, pp.171~187 (1999)
  23. Gronwall D., "Memory and information processing capacity after closed head injury", J Neurol Neurosurg Psychiatry, 44, pp.889~895 (1981)
  24. Bohnen N., "Post-traumatic and emotional symptoms in different subgroups of patients with mild head injury", Brain Inj, 6, pp.481~487 (1992)
  25. Brooks J., "Assessment of executive function in patients with mild traumatic brain injury", J Trauma, 46, pp.159~163 (1999)
  26. Parker RS., "IQ loss and emotional dysfunctions after mild head injury incurred in a motor vehicle accident", J Clin Psychol, 52, pp.32~43 (1996)
  27. Dikmen SS., "One year psychosocial outcome in head injury", J Int Neuropsychol Soc, 1, pp.67~77 (1995)
  28. Newcombe F., "Minor head injury : Pathophysiological or iatrogenic sequelae", J Neurol Neurosurg Psychiatry, 57, pp.709~716 (1994)
  29. Mathias JL., "Emotional and Cognitive Sequelae to Mild Traumatic Brain Injury", J Clin Exp Neuropsychol, 21, pp.200~215 (1999)
  30. Goldstein FC., "Cognitive and behavioral sequelae of closed head injury in older adults according to their significant others", J Neuropsychiatry Clin Neurosci, 11, pp.38~44 (1999)
  31. Lishman WA., "Physiogenesis and psychogenesis in the post-concussional syndrome", Br J Psychiatry, 153, pp.460~469 (1988)
  32. Kim YH., "PAI manual" (2001), Hak ji press
  33. Yeom TH, "K-WAIS Manual" (1992), Korea Guidance
  34. Kim HG, "Norms for Three-factors interpretation of K-WAIS Profile", Korean Journal of Clinical Psychology, 21, pp.631~645 (2002)
  35. Kim HG, "Rey-Kim Memory Test Manual" (1999), Neuropsychology press
  36. Kim HG, "Assessment of Memory Disorders Using", Rey-Kim Memory Test, 8, pp.29~48 (2001)
  37. Kim HG, "Kims Frontal-Executive Function Neuropsychological Test Manual" (2001), Neuropsychology Press
  38. Silver JM., "Neuropsychiatry of Traumatic Brain Injury", pp.3~41 (1994), American Psychiatric Press
  39. Mooney G., "Factors related to recovery after mild traumatic brain injury", Brain Inj, 19, pp.975~987 (2005)
  40. Jung AJ., "Personality and emotional Changes by Severity of Traumatic Brain Injury", Korean Journal of Health Psychology, 19, pp.379~393 (2004)
  41. Kweon SJ., "Personality Assessment Inventory Profiles of Patients with Mild and Severe Traumatic Brain Injury", Korean Journal of Biology Psychiatry, 12, pp.20~31 (2005)
  42. Kim HG., "Estimating Premorbid MQ", Korean Journal of Clinical Psychology, 20, pp.763~774 (2001)

관련 논문AI추천

경증 외상성 뇌손상 환자의 성별에 따른 증상과 기억과 신경 심리검사의 비교류석환대한신경정신의학회 · 신경정신의학2010 · 제49권 제1호후유장애 평가 의뢰된 환자에서의 신경인지기능의 임상적 특성강민희, 김원형, 김철응, 배재남, 이정섭, 정승호대한신경정신의학회 · 신경정신의학2010 · 제49권 제6호두부외상 환자에서 전두엽 손상과 신경인지기능 변화에 따른 주관적인 증상 연구기백석, 김준원, 박두병, 한덕현대한불안의학회 · 대한불안의학회지2012 · 제8권 제1호외상성 두부손상 환자에서 지능장애 및 기억장애 유무에 따른 정신과적 증상의 비교구본훈, 배대석대한생물치료정신의학회 · 생물치료정신의학2006 · 제12권 제2호외상성 뇌손상 환자군간 K-WAIS와 Rey-Kim 기억검사 반응 비교유지숙, 장은영한국임상심리학회 · Korean Journal of Clinical Psychology2003 · 제22권 제1호외상성 두부 손상 환자 집단의 한국판 성격 평가 질문지에 나타난 특성 분석오상우, 이지연, 지옥진한국재활심리학회 · 재활심리연구2010 · 제17권 제2호

이 간행물의 다른 논문 (7건)

정신신경면역학 개관김도훈pp. 147-151정신분열병과 면역학적 이상김용식, 정희연pp. 152-174사이토카인과 우울증김용구pp. 175-185대사증후군 집단의 심박동수 변이의 특징여도환, 강동묵, 김정연, 임성견, 우종민, 김원, 김정일, 조정진pp. 186-193알코올 의존 환자에서 한국어판 알코올 충동 척도 (Korean Alcohol Urge Questionnaire; AUQ-K)의 신뢰도와 타당도 연구김성곤, 변원탄, 김호찬, 이덕기, 강철중, 오광욱, 김철민, 김민정, 김효정, 김세훈pp. 204-210
원문 보기