본문 바로가기
KERD
논문KCI 등재

전이성 유두상 갑상선암 환자를 대상으로 투여한 알러젠 제거 옻나무 추출물의 종양 소퇴 1례

Tumor Regression Effect of Allergen-removed Rhus Verniciflua Stokes based Traditional Korean Medicine on a Patient with Metastatic Papillary Thyroid Carcinoma : Single Case Report

0

조회

0

다운로드

5

인용

0

참고문헌

키워드

주제분류한의학

초록

Papillary thyroid carcinoma is the most common type of thyroid malignancy. It has better prognosis and rarer incidence of distant metastasis than other types of thyroid malignancy. However, once distant metastasis happens, its result will be bad. They mostly spread to the lungs and bones, and rarely to the brain. We report a patient with a papillary thyroid carcinoma metastasis to the lymph nodes, the ribs, the brain, and the lungs. The patient underwent total thyroidectomy, radioiodine ablation, rib partial resection, and lung wedge resection. However, upon progress of metastasis, the patient insisted on being treated with traditional Korean medical treatment using allergen-removed Rhus Verniciflua Stokes (A-RVS) instead of the conventional treatment including chemotherapy. The size of the tumor partly decreased, and the patient showed no side effects. This case report brings forth the importance of a thorough study in papillary thyroid carcinomas and their metastasis from the traditional Korean medical point of view, along with the long-term effect of allergen-removed Rhus Verniciflua Stokes (A-RVS).

Abstract

Papillary thyroid carcinoma is the most common type of thyroid malignancy. It has better prognosis and rarer incidence of distant metastasis than other types of thyroid malignancy. However, once distant metastasis happens, its result will be bad. They mostly spread to the lungs and bones, and rarely to the brain. We report a patient with a papillary thyroid carcinoma metastasis to the lymph nodes, the ribs, the brain, and the lungs. The patient underwent total thyroidectomy, radioiodine ablation, rib partial resection, and lung wedge resection. However, upon progress of metastasis, the patient insisted on being treated with traditional Korean medical treatment using allergen-removed Rhus Verniciflua Stokes (A-RVS) instead of the conventional treatment including chemotherapy. The size of the tumor partly decreased, and the patient showed no side effects. This case report brings forth the importance of a thorough study in papillary thyroid carcinomas and their metastasis from the traditional Korean medical point of view, along with the long-term effect of allergen-removed Rhus Verniciflua Stokes (A-RVS).

참고문헌 (27)

  1. Carcangiu ML, "Papillary carcinoma of the thyroid: A clinicopathologic study of 241 cases treated at the University of Florence", Cancer, 55, pp.805~828 (1985)
  2. 박상재, "건칠(乾漆) 추출물(Nexia)의 Quality Control을 위한 기시법 및 안정성 연구", 대한암한의학회지, 11(1), pp.31~39 (2006)
  3. 박재우, "건칠추출물의 독성실험과 급성 림프구성 백혈병환자의 임상증례군 보고", 대한암한의학회지, 11(1), pp.1~21 (2006)
  4. 정종수, "알러젠 제거 옻나무 추출물 투여로 호전된 惡性黑色腫 환자 1례", 대한한방내과학회지, 28(3), pp.655~661 (2007), 대한한방내과학회
  5. Aguiar PH, "Unusual brain metastasis from papillary thyroid carcinoma: Case report", Neurosurgery, 49, pp.1008~1013 (2001)
  6. TP Links, "Life expectancy in differentiated tyroid cancer: a novel approach to survival analysis", Endocrine -Related Cancer, 12, pp.273~280 (2005)
  7. Hamady ZZ, "Surgical pathological second opinion in thyroid malignancy: impact on patients' management and prognosis", Eur J Surg Oncol, 31, pp.74~77 (2005)
  8. 남기현, "폐 전이 유두상 갑상선암의 예후인자 분석", 대한외과학회지, 68(3), pp.178~184 (2005), 대한외과학회
  9. Hoie J, "Distant metastasis in papillary thyroid cancer: A review of 91 patients", Cancer, 61, pp.1~6 (1988)
  10. Loh KC, "Pathological tumor-node- metastasis (pTNM) staging for papillary and follicular thyroid carcinomas: a retrospective analysis of 700 patients", J Clin Ecdocrinol Metab, 82, pp.3553~3562 (1997)
  11. DeGroot LJ, "Matural history, treatment, and course of papillary rhyroid carcinoma", J Clin Endocrinol Metab, 71, pp.414~424 (1990)
  12. Byar DP, "A prognostic index for thyroid carcinoma. A study of the E.O.R.T.C. Thyroid Cancer Cooperative Group", Eur J Cancer, 15, pp.1033~1041 (1979)
  13. Shaha AR, "Prognostic factors and risk group analysis in follicular carcinoma of the thyroid", Surgery, 118, pp.1131~1136 (1995)
  14. carcinoma treatment: initial analysis of staging and outcome. National Thyroid Cancer Treatment Cooperative Study Registry Group, "Cancer", 1998, 1012~1021
  15. Cady B, "An expanded view of risk-group definition in differentiated thyroid carcinoma", Surgery, 104, pp.947~953 (1988)
  16. 김원배, "이재복, 최영식 등. 갑상선 결절 및 암 진료 권고안", 대한내분비학회지, 22(3), pp.157~187 (2007)
  17. Links TP, "Life expectancy in differentiated thyroid cancer: a novel approach to survival analysis", Endocrine -Related Cancer, 12, pp.273~280 (2005)
  18. 최승훈, "한의학의 종양에 대한 인식과 병리론", 대한한방종양학회지, 1(1), pp.11~28 (1995)
  19. 송미선, "乾漆에 対한 문헌적 考察", 대한한방부인과학회지, 15(1), pp.60~76 (2002)
  20. 최원철, "법제 옻나무 추출물의 혈관형성저해 및 항암효과에 관한 연구", 동의생리병리학회지, 20(4), pp.825~829 (2006), 대한동의병리학회
  21. Kim JH, "Inhibition of cell cycle progression via p27Kip1 upregulation and apoptosis induction by an ethanol extract of Rhus Verniciflua Stokes in AGS gastric cancer cells", Int J Mol Med, 18(1), pp.201~208 (2006)
  22. Lee SJ, "6 kDa glycoprotein isolated from Rhus Verniciflua Stokes inhibits G", GO-induced mitochondrial apoptotic signal pathways in BNL CL.2 cells, 2005, pp.97(6), 399~405
  23. Jang HS, "Flavonoids purified from Rhus Verniciflua Stokes actively inhibit cell growth and induce apoptosis in human osteosarcoma cells", Biochim Biophys Acta, 1726(3), pp.309~316 (2005)
  24. Oh PS, "Hypolipidemic and antioxidative effects of the plant glycoprotein (36kDa) from Rhus Verniciflua Stokes fruit in Triton WR-1339-induced hyperlipidemic mice", Biosci Biotechnol Biochem, 70(2), pp.447~456 (2006)
  25. Jung CH, "Phenolic-rich fraction from Rhus Verniciflua Stokes(RVS) supress inflammatory response via NF-kappaB and JNK pathway in lipopolysaccharide-induced RAW 264.7 macrophages", J Ethnopharmacol, 110(3), pp.490~497 (2007)
  26. 윤성우, "건칠추출물의 Quality Control을 위한 기시법 및 안정성 연구", 대한암한의학회지, 11(1), pp.1~22 (2006)
  27. Se-Hyun Kim, "Effect of Nexia for Advanced Non-small cell Lung Cancer on Patients's Survival and Quality of Life: a Prospective Cohort Study", The 2nd International East-West Cancer Symposium (2007)

관련 논문AI추천

이 간행물의 다른 논문 (26건)