논문KCI 등재
줄기세포 치료를 통한 대뇌 손상 동물의 트레드밀 운동 재활 입증
Motor rehabilitation proof of cerebral injured animal by stem cell therapy
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본 연구에서는 중간 대뇌 동맥 결찰술에 의한 뇌손상시 줄기세포 이식의 영향과 운동재활적 기능이 향상됨을 입증하고자 한다. 실험 연구는 줄기세포 이식이 뇌허혈 형성의 억제와 운동기능의 향상과 관련이 있다는 것을 발견하였으며 상대적으로 대조군 동물 실험 모델들은 동맥 결찰술 수술을 통해 조직학적 손상과 더불어 기능학적 저하로 나타났으며 손상회복이 되지 않아서 운동재활 향상을 가져오지 않은 결과를 보여준다. 따라서, 실험군에서 보여준 줄기세포 이식을 통한 신경학적 재생과 운동기능 회복에 관한 관련성을 본 연구에서 제시하고자 하였다.
Abstract
In this study, we prove the effects of stem cell transplantation and motor rehabilitation on brain injury produced by application of middle cerebral artery occlusion. We found that stem cell transplantation is associated with suppression of cavity formation and improvement of motor function. In contrast, the control animals remained severely showed hitological impairment and functional deterioration throughout artery occlusion. Therefore, we suggest the correlation between neurological regeneration and motor rehabilitation through stem cell transplantation in the experimental group.
참고문헌 (22)
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