대학신입생의 코티졸-DHEA 비율 변화의 잠재프로파일 분석 및 예측요인 탐색
Analyzing Latent Profile and Investigating Predictive Factors of Cortisol/DHEA Ratio among University Freshmen
2
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
연구목적: 본 연구의 목적은 코티졸-DHEA 비율의 잠재계층 유형과 잠재계층 유형을 예측하는 요인을 규명하는 것이다. 연구방법: 170명의 대학신입생을 대상으로 타액 코티졸과 DHEA을 채취하고 잠재프로파일 분석과 로지스틱 회귀분석을 실시하였다. 연구결과: 분석결과는 다음과 같다. 첫째, 코티졸-DHEA 비율의 잠재집단 유형은 3가지 유형으로 나타났다:‘안정적으로 낮은’ 유형(54.1%, 유형1), ‘감소하는’ 유형(32.4%, 유형2), ‘불안정하게 높은’ 유형(13.5%, 유형3). 둘째, 잠재집단 유형 예측요인을 살펴보면, 먼저 유형 2를 유형 1과 비교할 때 우울(p < .01)이 유의한 예측요인으로 나타났다. 다음으로 유형 3을 유형 1과 비교할 때 성별(p < .05)과 신체화 증상(p < .05), 유형3을 유형 2와 비교할 때 성별(p < .05)이 유의한 예측요인으로 나타났다. 결론: 코티졸-DHEA 비율에 따른 3개의 잠재집단은 유의한 이질성을 보였으며, 성별은 코티졸-DHEA 비율의 잠재집단 유형을 예측하는 가장 주요한 요인이었다.
Abstract
Objective: This study aimed to identify the types of cortisol/DHEA ratio and predict factors affecting the types of cortisol/DHEA ratio. Methods: The participants were 170 freshmen from the University. The data were analyzed using R 3.6.1 version and the tidyLPA package for latent analysis. Results: Three latent classes of cortisol/DHEA ratio were identified: low and stable (54.1% of the sample, type 1), decreasing (32.4% of the sample, type 2), and high and unstable (13.5% of the sample, type 3). On comparing latent type 1 with latent type 2, BSI_depression (p < .01) was found to be significant. On comparing latent type 1 with latent type 3, gender (p < .05) and BSI_somatization (p < .05) were found to be significant. On comparing latent type 2 with latent type 3, gender (p < .05) was found to be significant. Conclusion: The results showed significant heterogeneity in the types of cortisol/DHEA ratio; gender was an important predictor of the cortisol/DHEA ratio.
참고문헌 (52)
- 고미숙, "대학생의 인지적 정서조절과 회복탄력성에 따른 스트레스, 우울 및 자살생각의 차이", 인지발달중재학회지, 7(3), pp.69~86 (2016), 인지발달중재학회
- 김법신, "집단놀이치료가 장애아동 형제자매의 스트레스와 우울, 자아존중감에 미치는 효과", 인지발달중재학회지, 4(2), pp.21~34 (2013), 인지발달중재학회
- 김영복, "대학 신입생의 음주행동과 건강생활실천, 정신건강수준 간의 관련성", 보건교육건강증진학회지, 34(5), pp.95~105 (2017), 한국보건교육건강증진학회[DOI]
- 김지향, "대학생의 건강생활 습관과 스트레스에 관한 연구", 동아시아식생활학회지, 14(3), pp.207~216 (2004), 동아시아식생활학회
- "대학생 46%, ‘만성스트레스’에 시달려" (2010)[URL]
- 여정희, "남녀 대학 신입생의 건강습관과 영향요인", 한국간호교육학회지, 16(2), pp.283~291 (2010), 한국간호교육학회
- 이성희, "대학 신입생 흡연자의 흡연특성, 건강상태와 금연의도", 예술인문사회 융합 멀티미디어 논문지, 7(12), pp.601~610 (2017), 사단법인 인문사회과학기술융합학회[DOI]
- 정은영, "서울 지역 대학생의 기호품 섭취와 식생활 양상과의 관계", 석사, 가정학, pp.2000
- 허인자, "대학생들의 아침식사습관과 관련된 요인에 관한 연구", 보건교육건강증진학회지, 16(2), pp.121~135 (1999)
- 안영우, "만성적인 스트레스로 인한 부신고갈과 피로현상", 대한의사협회지, 54(1), pp.81~87 (2011), 대한의사협회
- Angold, A., "Adolescent depression, cortisol and DHEA", Psychological Medicine, 33(4), pp.573~581 (2003)[DOI]
- Bauer, M. E., "Stress, glucocorticoids and ageing of the immune system", Stress, 8(1), pp.69~83 (2005)[DOI]
- Belloc, N. B., "Relationship of physical health status and health practices", Preventive Medicine, 1(3), pp.409~421 (1972)[DOI]
- Brillon, D. J., "Effect of cortisol on energy expenditure and amino acid metabolism in humans", American Journal of Physiology-Endocrinology and Metabolism, 268(3), pp.E501~E513 (1995)[DOI]
- Chrousos, G. P., "A healthy body in a healthy mind-and vice versa-the damaging power of"uncontrollable"stress", The Journal of Clinical Endocrinology & Metabolism, 83(6), pp.1842~1845 (1998)[DOI]
- Derogatis, L. R., "BSI 18, Brief Symptom Inventory 18: Administration, Scoring and Procedure Manual" (2001), NCS Pearson
- Ditzen, B., "Adult attachment and social support interact to reduce psychological but not cortisol responses to stress", Journal of Psychosomatic Research, 64(5), pp.479~486 (2008)[DOI]
- Fraser, R., "Cortisol effects on body mass, blood pressure, and cholesterol in the general population", Hypertension, 33(6), pp.1364~1368 (1999)[DOI]
- Gallagher, P., "Cortisol", DHEA ratios in depression, 2002, pp.26(3), 410~
- Goodyer, I. M., "Adrenal steroid secretion and major depression in 8- to 16-year-olds, III. Influence of cortisol", DHEA ratio at presentation on subsequent rates of disappointing life events and persistent major depression, 1998, pp.28(2), 265~273
- Goodyer, I. M., "Psychoendocrine antecedents of persistent first-episode major depression in adolescents : a community-based longitudinal enquiry", Psychological Medicine, 33(4), pp.601~610 (2003)[DOI]
- Guilliams, T. G., "Chronic stress and the HPA axis", The Standard, 9(2), pp.1~12 (2010)[DOI]
- Harbuz, M., "Neuroendocrine Function and Chronic Inflammatory Stress", Experimental Physiology, 87(5), pp.519~525 (2004)[DOI]
- Heinze, K., "Longer-term increased cortisol levels in young people with mental health problems", Psychiatry Research, 236, pp.98~104 (2016)[DOI]
- Hellhammer, D. H., "Salivary cortisol as a biomarker in stress research", Psychoneuroendocrinology, 34(2), pp.163~171 (2009)[DOI]
- Jameison, K. 1., "Glucocorticoids and cognitive function : from physiology to pathophysiology", Human Psychopharmacology, 16(4), pp.293~302 (2001)[DOI]
- Jefferies, W. M., "Cortisol and immunity", Medical Hypotheses, 34(3), pp.198~208 (1991)[DOI]
- Kalmijn, S., "A prospective study on cortisol, dehydroepiandrosterone sulfate, and cognitive function in the elderly", The Journal of Clinical Endocrinology &Metabolism, 83(10), pp.3487~3492 (1998)[DOI]
- Kroboth, P. D., "DHEA and DHEA-S : A review", The Journal of Clinical Pharmacology, 39(4), pp.327~348 (1999)[DOI]
- Lam, J. C. W., "Greater lifetime stress exposure predicts blunted cortisol but heightened DHEA responses to acute stress", Stress Health, 35(1), pp.15~26 (2019)[DOI]
- Li, M., "Relationships among stress coping, secure attachment, and the trait of resilience among Taiwanese college students", College Student Journal, 42(2), pp.312~325 (2008)[DOI]
- Lubke, G., "Performance of Factor Mixture Models as a Function of Model Size, Covariate Effects, and Class-Specific Parameters, Structural Equation Modeling", A Multidisciplinary Journal, 14(1), pp.26~47 (2007)[DOI]
- Michael, A., "Altered salivary dehydroepiandrosterone levels in major depression in adults", Biological Psychiatry, 48(10), pp.989~995 (2000)[DOI]
- Newcomer, J. W., "Decreased memory performance in healthy humans induced by stress-level cortisol treatment", Archives Of General Psychiatry, 56(6), pp.527~533 (1999)[DOI]
- Oskis, A., "Anxious attachment style and salivary cortisol dysregulation in healthy female children and adolescents", The Journal of Child Psychology and Psychiatry, 52(2), pp.111~118 (2011)[DOI]
- Quirin, M, "HPA system regulation and adult attachment anxiety : Individual differences in reactive and awakening cortisol", Psychoneuroendocrinology, 33, pp.581~590 (2008)[DOI]
- Raison, C. L., "The neuroimmunology of stress and depression", Seminars in Clinical Neuropsychiatry, 6(4), pp.277~294 (2001)[DOI]
- Ramaswamy, V., "An empirical pooling approach for estimating marketing mix elasticities with PIMS data", Marketing Science, 12(1), pp.103~124 (1993)
- Rief, W., "Cortisol and somatization", Biological Psychology, 53(1), pp.13~23 (2000)[DOI]
- Santana, M. D., "Cortisol Levels and Autonomic Control of Heart Rate in Healthy Subjects", Acta Medica Martiniana, 17(2), pp.5~14 (2017)[DOI]
- Sateia M. J., "Insomnia", The Lancet, 364(9449), pp.1959~1973 (2004)[DOI]
- Smith, K. J., "Skipping breakfast : Longitudinal associations with cardiometabolic risk factors in the Childhood Determinants of Adult Health Study", The American Journal of Clinical Nutrition, 92(6), pp.1316~1325 (2010)[DOI]
- Straub, R. H., "The endotoxin-induced increase of cytokines is followed by an increase of cortisol relative to dehydroepiandrosterone(DHEA)in healthy male subjects", Journal of Endocrinology, 175(2), pp.467~474 (2002)[DOI]
- Stubbs, B., "An examination of the anxiolytic effects of exercise for people with anxiety and stress-related disorders : A meta-analysis", Psychiatry Research, 249, pp.102~108 (2017)[DOI]
- Tafet, G. E., "Psychoneuroendocrinological studies on chronic stress and depression", Annals of the New York Academy of Sciences, 1032, pp.276~278 (2004)[DOI]
- Van Voorhees, E. E., "Association of DHEA, DHEAS, and cortisol with childhood trauma exposure and posttraumatic stress disorder", International Clinical Psychopharmacology, 29(1), pp.56~62 (2014)[DOI]
- Walker, B. R., "Increased glucocorticoid activity in men with cardiovascular risk factors", Hypertension, 31(4), pp.891~895 (1998)[DOI]
- Wemm, S., "0 The role of DHEA in relation to problem solving and academic performance", Biological Psychology, 85(1), pp.53~61 (2010)[DOI]
- Whitworth, J. A., "Cardiovascular Consequences of Cortisol Excess", Vascular Health and Risk Management, 1(4), pp.291~299 (2005)[DOI]
- Wolf, O. T., "A single administration of dehydroepiandrosterone does not enhance memory performance in young healthy adults, but immediately reduces cortisol levels", Biological Psychiatry, 42(9), pp.845~848 (1997)[DOI]
- Young, A. H., "Elevation of the cortisoldehydroepiandrosterone ratio in drug-free depressed patients", American Journal of Psychiatry, 159(7), pp.1237~1239 (2002)[DOI]
- Young, E. A., "Twenty-four-hour ACTH and cortisol pulsatility in depressed women", Neuropsychopharmacology, 25(2), pp.267~276 (2001)[DOI]
