본문 바로가기
KERD
논문KCI 등재

대학신입생의 코티졸-DHEA 비율 변화의 잠재프로파일 분석 및 예측요인 탐색

Analyzing Latent Profile and Investigating Predictive Factors of Cortisol/DHEA Ratio among University Freshmen

2

조회

0

다운로드

1

인용

0

참고문헌

키워드

주제분류심리과학

초록

연구목적: 본 연구의 목적은 코티졸-DHEA 비율의 잠재계층 유형과 잠재계층 유형을 예측하는 요인을 규명하는 것이다. 연구방법: 170명의 대학신입생을 대상으로 타액 코티졸과 DHEA을 채취하고 잠재프로파일 분석과 로지스틱 회귀분석을 실시하였다. 연구결과: 분석결과는 다음과 같다. 첫째, 코티졸-DHEA 비율의 잠재집단 유형은 3가지 유형으로 나타났다:‘안정적으로 낮은’ 유형(54.1%, 유형1), ‘감소하는’ 유형(32.4%, 유형2), ‘불안정하게 높은’ 유형(13.5%, 유형3). 둘째, 잠재집단 유형 예측요인을 살펴보면, 먼저 유형 2를 유형 1과 비교할 때 우울(p < .01)이 유의한 예측요인으로 나타났다. 다음으로 유형 3을 유형 1과 비교할 때 성별(p < .05)과 신체화 증상(p < .05), 유형3을 유형 2와 비교할 때 성별(p < .05)이 유의한 예측요인으로 나타났다. 결론: 코티졸-DHEA 비율에 따른 3개의 잠재집단은 유의한 이질성을 보였으며, 성별은 코티졸-DHEA 비율의 잠재집단 유형을 예측하는 가장 주요한 요인이었다.

Abstract

Objective: This study aimed to identify the types of cortisol/DHEA ratio and predict factors affecting the types of cortisol/DHEA ratio. Methods: The participants were 170 freshmen from the University. The data were analyzed using R 3.6.1 version and the tidyLPA package for latent analysis. Results: Three latent classes of cortisol/DHEA ratio were identified: low and stable (54.1% of the sample, type 1), decreasing (32.4% of the sample, type 2), and high and unstable (13.5% of the sample, type 3). On comparing latent type 1 with latent type 2, BSI_depression (p < .01) was found to be significant. On comparing latent type 1 with latent type 3, gender (p < .05) and BSI_somatization (p < .05) were found to be significant. On comparing latent type 2 with latent type 3, gender (p < .05) was found to be significant. Conclusion: The results showed significant heterogeneity in the types of cortisol/DHEA ratio; gender was an important predictor of the cortisol/DHEA ratio.

참고문헌 (52)

  1. 고미숙, "대학생의 인지적 정서조절과 회복탄력성에 따른 스트레스, 우울 및 자살생각의 차이", 인지발달중재학회지, 7(3), pp.69~86 (2016), 인지발달중재학회
  2. 김법신, "집단놀이치료가 장애아동 형제자매의 스트레스와 우울, 자아존중감에 미치는 효과", 인지발달중재학회지, 4(2), pp.21~34 (2013), 인지발달중재학회
  3. 김영복, "대학 신입생의 음주행동과 건강생활실천, 정신건강수준 간의 관련성", 보건교육건강증진학회지, 34(5), pp.95~105 (2017), 한국보건교육건강증진학회[DOI]
  4. 김지향, "대학생의 건강생활 습관과 스트레스에 관한 연구", 동아시아식생활학회지, 14(3), pp.207~216 (2004), 동아시아식생활학회
  5. "대학생 46%, ‘만성스트레스’에 시달려" (2010)[URL]
  6. 여정희, "남녀 대학 신입생의 건강습관과 영향요인", 한국간호교육학회지, 16(2), pp.283~291 (2010), 한국간호교육학회
  7. 이성희, "대학 신입생 흡연자의 흡연특성, 건강상태와 금연의도", 예술인문사회 융합 멀티미디어 논문지, 7(12), pp.601~610 (2017), 사단법인 인문사회과학기술융합학회[DOI]
  8. 정은영, "서울 지역 대학생의 기호품 섭취와 식생활 양상과의 관계", 석사, 가정학, pp.2000
  9. 허인자, "대학생들의 아침식사습관과 관련된 요인에 관한 연구", 보건교육건강증진학회지, 16(2), pp.121~135 (1999)
  10. 안영우, "만성적인 스트레스로 인한 부신고갈과 피로현상", 대한의사협회지, 54(1), pp.81~87 (2011), 대한의사협회
  11. Angold, A., "Adolescent depression, cortisol and DHEA", Psychological Medicine, 33(4), pp.573~581 (2003)[DOI]
  12. Bauer, M. E., "Stress, glucocorticoids and ageing of the immune system", Stress, 8(1), pp.69~83 (2005)[DOI]
  13. Belloc, N. B., "Relationship of physical health status and health practices", Preventive Medicine, 1(3), pp.409~421 (1972)[DOI]
  14. Brillon, D. J., "Effect of cortisol on energy expenditure and amino acid metabolism in humans", American Journal of Physiology-Endocrinology and Metabolism, 268(3), pp.E501~E513 (1995)[DOI]
  15. Chrousos, G. P., "A healthy body in a healthy mind-and vice versa-the damaging power of"uncontrollable"stress", The Journal of Clinical Endocrinology & Metabolism, 83(6), pp.1842~1845 (1998)[DOI]
  16. Derogatis, L. R., "BSI 18, Brief Symptom Inventory 18: Administration, Scoring and Procedure Manual" (2001), NCS Pearson
  17. Ditzen, B., "Adult attachment and social support interact to reduce psychological but not cortisol responses to stress", Journal of Psychosomatic Research, 64(5), pp.479~486 (2008)[DOI]
  18. Fraser, R., "Cortisol effects on body mass, blood pressure, and cholesterol in the general population", Hypertension, 33(6), pp.1364~1368 (1999)[DOI]
  19. Gallagher, P., "Cortisol", DHEA ratios in depression, 2002, pp.26(3), 410~
  20. Goodyer, I. M., "Adrenal steroid secretion and major depression in 8- to 16-year-olds, III. Influence of cortisol", DHEA ratio at presentation on subsequent rates of disappointing life events and persistent major depression, 1998, pp.28(2), 265~273
  21. Goodyer, I. M., "Psychoendocrine antecedents of persistent first-episode major depression in adolescents : a community-based longitudinal enquiry", Psychological Medicine, 33(4), pp.601~610 (2003)[DOI]
  22. Guilliams, T. G., "Chronic stress and the HPA axis", The Standard, 9(2), pp.1~12 (2010)[DOI]
  23. Harbuz, M., "Neuroendocrine Function and Chronic Inflammatory Stress", Experimental Physiology, 87(5), pp.519~525 (2004)[DOI]
  24. Heinze, K., "Longer-term increased cortisol levels in young people with mental health problems", Psychiatry Research, 236, pp.98~104 (2016)[DOI]
  25. Hellhammer, D. H., "Salivary cortisol as a biomarker in stress research", Psychoneuroendocrinology, 34(2), pp.163~171 (2009)[DOI]
  26. Jameison, K. 1., "Glucocorticoids and cognitive function : from physiology to pathophysiology", Human Psychopharmacology, 16(4), pp.293~302 (2001)[DOI]
  27. Jefferies, W. M., "Cortisol and immunity", Medical Hypotheses, 34(3), pp.198~208 (1991)[DOI]
  28. Kalmijn, S., "A prospective study on cortisol, dehydroepiandrosterone sulfate, and cognitive function in the elderly", The Journal of Clinical Endocrinology &Metabolism, 83(10), pp.3487~3492 (1998)[DOI]
  29. Kroboth, P. D., "DHEA and DHEA-S : A review", The Journal of Clinical Pharmacology, 39(4), pp.327~348 (1999)[DOI]
  30. Lam, J. C. W., "Greater lifetime stress exposure predicts blunted cortisol but heightened DHEA responses to acute stress", Stress Health, 35(1), pp.15~26 (2019)[DOI]
  31. Li, M., "Relationships among stress coping, secure attachment, and the trait of resilience among Taiwanese college students", College Student Journal, 42(2), pp.312~325 (2008)[DOI]
  32. Lubke, G., "Performance of Factor Mixture Models as a Function of Model Size, Covariate Effects, and Class-Specific Parameters, Structural Equation Modeling", A Multidisciplinary Journal, 14(1), pp.26~47 (2007)[DOI]
  33. Michael, A., "Altered salivary dehydroepiandrosterone levels in major depression in adults", Biological Psychiatry, 48(10), pp.989~995 (2000)[DOI]
  34. Newcomer, J. W., "Decreased memory performance in healthy humans induced by stress-level cortisol treatment", Archives Of General Psychiatry, 56(6), pp.527~533 (1999)[DOI]
  35. Oskis, A., "Anxious attachment style and salivary cortisol dysregulation in healthy female children and adolescents", The Journal of Child Psychology and Psychiatry, 52(2), pp.111~118 (2011)[DOI]
  36. Quirin, M, "HPA system regulation and adult attachment anxiety : Individual differences in reactive and awakening cortisol", Psychoneuroendocrinology, 33, pp.581~590 (2008)[DOI]
  37. Raison, C. L., "The neuroimmunology of stress and depression", Seminars in Clinical Neuropsychiatry, 6(4), pp.277~294 (2001)[DOI]
  38. Ramaswamy, V., "An empirical pooling approach for estimating marketing mix elasticities with PIMS data", Marketing Science, 12(1), pp.103~124 (1993)
  39. Rief, W., "Cortisol and somatization", Biological Psychology, 53(1), pp.13~23 (2000)[DOI]
  40. Santana, M. D., "Cortisol Levels and Autonomic Control of Heart Rate in Healthy Subjects", Acta Medica Martiniana, 17(2), pp.5~14 (2017)[DOI]
  41. Sateia M. J., "Insomnia", The Lancet, 364(9449), pp.1959~1973 (2004)[DOI]
  42. Smith, K. J., "Skipping breakfast : Longitudinal associations with cardiometabolic risk factors in the Childhood Determinants of Adult Health Study", The American Journal of Clinical Nutrition, 92(6), pp.1316~1325 (2010)[DOI]
  43. Straub, R. H., "The endotoxin-induced increase of cytokines is followed by an increase of cortisol relative to dehydroepiandrosterone(DHEA)in healthy male subjects", Journal of Endocrinology, 175(2), pp.467~474 (2002)[DOI]
  44. Stubbs, B., "An examination of the anxiolytic effects of exercise for people with anxiety and stress-related disorders : A meta-analysis", Psychiatry Research, 249, pp.102~108 (2017)[DOI]
  45. Tafet, G. E., "Psychoneuroendocrinological studies on chronic stress and depression", Annals of the New York Academy of Sciences, 1032, pp.276~278 (2004)[DOI]
  46. Van Voorhees, E. E., "Association of DHEA, DHEAS, and cortisol with childhood trauma exposure and posttraumatic stress disorder", International Clinical Psychopharmacology, 29(1), pp.56~62 (2014)[DOI]
  47. Walker, B. R., "Increased glucocorticoid activity in men with cardiovascular risk factors", Hypertension, 31(4), pp.891~895 (1998)[DOI]
  48. Wemm, S., "0 The role of DHEA in relation to problem solving and academic performance", Biological Psychology, 85(1), pp.53~61 (2010)[DOI]
  49. Whitworth, J. A., "Cardiovascular Consequences of Cortisol Excess", Vascular Health and Risk Management, 1(4), pp.291~299 (2005)[DOI]
  50. Wolf, O. T., "A single administration of dehydroepiandrosterone does not enhance memory performance in young healthy adults, but immediately reduces cortisol levels", Biological Psychiatry, 42(9), pp.845~848 (1997)[DOI]
  51. Young, A. H., "Elevation of the cortisoldehydroepiandrosterone ratio in drug-free depressed patients", American Journal of Psychiatry, 159(7), pp.1237~1239 (2002)[DOI]
  52. Young, E. A., "Twenty-four-hour ACTH and cortisol pulsatility in depressed women", Neuropsychopharmacology, 25(2), pp.267~276 (2001)[DOI]

관련 논문AI추천

이 간행물의 다른 논문 (6건)