재래돼지에서 6개 SNP와 경제형질, 고기품질 간의 연관성 분석
Association of 6 SNPs and Economic and Meat Quality Traits in Korean Native Pigs
2
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
The aim of this study is to investigate the genetic interrelationships between economic or meat quality traits (birth weight, weaning weight, average daily gain, market weight, carcass weight, backfat thickness, water, ash, fat, protein, water holding capacity and pH) and 6 SNPs located on six selected candidate genes (MC4R, PGK2, TNNI1, TNNI2, PIK3C3, and CTSK) in Korean native pigs. The genotypes were identified in the 6 SNPs by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) procedure, and association of the genotype on economically important traits was analyzed by general liner model. According to the analyzed results, the MC4R c.1426A>G was correlated with birth weight (p=0.032) and the PGK2 g.122T>G was associated with pH (p=0.026). These findings obtained in the present revealed that the each SNPs of MC4R and PGK2 could be useful as potential genetic markers for birth weight and pH in Korean native pigs, respectively.
Abstract
The aim of this study is to investigate the genetic interrelationships between economic or meat quality traits (birth weight, weaning weight, average daily gain, market weight, carcass weight, backfat thickness, water, ash, fat, protein, water holding capacity and pH) and 6 SNPs located on six selected candidate genes (MC4R, PGK2, TNNI1, TNNI2, PIK3C3, and CTSK) in Korean native pigs. The genotypes were identified in the 6 SNPs by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) procedure, and association of the genotype on economically important traits was analyzed by general liner model. According to the analyzed results, the MC4R c.1426A>G was correlated with birth weight (p=0.032) and the PGK2 g.122T>G was associated with pH (p=0.026). These findings obtained in the present revealed that the each SNPs of MC4R and PGK2 could be useful as potential genetic markers for birth weight and pH in Korean native pigs, respectively.
참고문헌 (26)
- Benoit, S., "CNS melancortin system involvement in the regulation of food intake", Horm. & Behav, 37(4), pp.299~305 (2000)
- 조규호, "듀록 품종의 Melanocortin-4 Receptor(MC4R) 유전자와 성장형질과의 연관성 분석", 한국동물자원과학회지, 49(4), pp.437~442 (2007), 한국동물자원과학회
- 조수현, "재래돼지의 출하체중별 도체수율 및 육질특성", 한국동물자원과학회지, 49(4), pp.523~530 (2007), 한국동물자원과학회
- Choi, Y. S., "Studies on the pork quality of Korean native black pigs and its improvement through dietary manipulation", 박사, pp.2004
- Cone, R. D., "The centeal melancortin system and energy homeostasis", Tren. Endo. Metab, 10, pp.211~216 (1999)
- Drogemuller, C., "Candidate gene markers for litter size in different German pig lines", J Anim. Sci, 79(10), pp.2565~2570 (2001)
- Fontanesi, L., "The insulin-like growth factor 2 (IGF2) gene intron3-g.3072G>A polymorphism is not the only sus scrofa chromosome 2p mutation affecting meat production and carcass traits in pigs: Evidence frome the effects of a cathepsin D (CTSD) gene polymorphism", American Soci. of Anim. Sci, 88, pp.2235~2245 (2010)
- Hernandez-Sanchez, J., "Candidate gene analysis for quantitative traits using the transmission disequilibrium test; The example of the melanocortin 4-receptor in pigs", Genet, 164, pp.637~644 (2003)
- Hirose, K., "Association of an SNP marker in exon 24 of a class 3 phosphoinositide- 3-kinase (PIK3C3) gene with production traits in Duroc pigs", J. Anim. Sci, 82, pp.46~51 (2011)
- Hofmann, K., "NeunesUber die bestimmung der wasserbindung des fleisches mit hilfe der filterpapierpressmethode", Fleischwiry, 62, pp.87~92 (1982)
- Houston, R. D., "A melanocortin-4 receptor (MC4R) polymorphism is associated with performance traits in divergently selected large white pig populations", Anim. Genet, 35, pp.386~390 (2004)
- 장홍철, "돼지 PGK 2 유전자의 단일염기다형성 및 성장 형질과의 연관성 구명", 한국동물자원과학회지, 53(1), pp.15~22 (2011), 한국동물자원과학회
- Jin, S. K., "Physicochemical characteristics of longissimus muscle between the Korean native pig and Landrace", Korean J. Food Sci. Anim. Resour, 21(2), pp.142~148 (2001)
- Kim, K. S., "Rapid communication : linkage and. physical mapping of the porcine melanocortin 4 receptor (MC4R) gene", J. Anim. Sci, 78(3), pp.791~792 (1999)
- Kim, K. S., "A missense variant of the porcine melanocortin-4 reccptor (MC4R) gene is associated with fatness, growth, and feed intake traits", Mamm. Gemo, 11, pp.131~135 (2000)
- Kim, K. S., "Functional and phylogenetic analyses of a melanocortin-4 receptor mutation in domestic pig", Dome. Anim. Endo, 26, pp.75~86 (2004)
- 김명직, "한국 재래 돼지와 듀록의 경제형질과 후보 유전자 다형성간의 연관성 분석", 한국수정란이식학회지, 21(4), pp.273~280 (2006), 한국수정란이식학회
- Kwon, O. S., "Korean native black pigs. Standard guideline for farmer", Rural Development Administration, ~ (2001)
- Lay, A. J., "Phosphoglycerate kinase acts in tumour angiogenesis as a disulphide reductase", Nature, 208, pp.869~873 (2000)
- Marshall, T. C., "Statistical confidence for likelihood-based paternity inference in natural populations", Mol. Ecol, 7, pp.639~655 (1998)
- Mas, M. T., "Active human-yeast chimeric phosphoglycerate kinases engineered by domain interchange", Science, 233, pp.788~790 (1986)
- Meidtner, K., "Association of the melanocortin 4 reccptor with feed intake and daily gain in F2 Mangalitsa X Pietrain pigs", Amim. Genet, 37, pp.245~247 (2006)
- Seyfert, M., "Influence of carbon monoxide in package atmospheres containing oxygen on colour, reducing activity, and oxygen consumption of five bovine muscles", Meat Sci, 75, pp.432~442 (2007)
- Thaller, G., "Effects of DGAT1 variants on milk production traits in German cattle breeds", J. Anim. Sci, 81(8), pp.1911~1918 (2003)
- Xu, Z. Y., "Identification of three novel SNPs and association with carcass traits in porcine TNNI1 and TNNI2", Mol. Biol. Rep, 37, pp.3609~3613 (2010)
- Yoo, C. K., "QTL analysis of back fat thickness and carcass pH in an F2 intercross between Landrace and Korean native pigs", Mol. Biol. Rep, 39, pp.8327~8833 (2012)