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실제 협착된 혈관에서의 혈류유동예측에 대한 해석적 연구

Numerical Study on Prediction of Hemodynamics on Actually Stenosed Blood vessel

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키워드

주제분류기계공학

초록

Angiography has excellent advantages to visually observe the internal morphology of the stenosed blood vessel. For OCT(Optical coherence tomography), it is possible to directly provide a reliable two-dimensional cross-sectional information as compared to conventional angiography. In the present study, both velocity and wall shear stress distributions were numerically investigated using stenosed blood vessel models (0%, 25%, 50%, and 75% stenotic expansion rate). The blood vessel geometry was prepared based on the human stenotic aorta from OCT image. Commercially available software (CATIA V5) was used to reconstruct 3D blood vessel for numerial analysis. Pulsatile blood flow boundary condition was applied. The numerical study could help our understanding of the hemodynamic differences in a stenosed blood vessel.

Abstract

Angiography has excellent advantages to visually observe the internal morphology of the stenosed blood vessel. For OCT(Optical coherence tomography), it is possible to directly provide a reliable two-dimensional cross-sectional information as compared to conventional angiography. In the present study, both velocity and wall shear stress distributions were numerically investigated using stenosed blood vessel models (0%, 25%, 50%, and 75% stenotic expansion rate). The blood vessel geometry was prepared based on the human stenotic aorta from OCT image. Commercially available software (CATIA V5) was used to reconstruct 3D blood vessel for numerial analysis. Pulsatile blood flow boundary condition was applied. The numerical study could help our understanding of the hemodynamic differences in a stenosed blood vessel.

참고문헌 (8)

  1. Kim, H.H., "Analysis of Bypass Grafting Effects in Stenosed Coronary Arteries", Proceeding of the KSME Fluids Engineering Division Fall Meeting, pp.201~206 (2001)
  2. A.Qiao, "Medical application oriented blood flow simulation", CLINICAL BIOMECHANICS, 23, pp.130~136 (2008)
  3. M. Toloui, "A numerical study of the effects of blood rheology and vessel deformability on the hemodynamics of carotid bifurcation", Scientia Iranica B, 19, pp.119~126 (2012)
  4. M. Willemet, "Inlet boundary conditions for blood flow simulations in truncated arterial networks", Journal of Biomechanics, 44, pp.897~903 (2011)
  5. K. Melih Guleren, "Numerical flow analysis of coronary arteries through concentric and eccentric stenosed geometries", Journal of Biomechanics, 46, pp.1043~1052 (2013)
  6. Kim S, "A method of isolating surface tension and yield stress effects in a U-shaped scanning capillary tube viscometer", Journal of Non-newtonian Fluid Mechanics, (103), pp.205~219 (2002)
  7. L. R. John, "Forward electrical transmission line model of the human arterial system", Medical & Biological Engineering & Computing, 42, pp.312~321 (2004)

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