본문 바로가기
KERD
논문KCI 등재

An Update on the Prevalence of Allergic Rhinitis in Korea, and Correlation with Hypertension, Obesity and Smoking

2

조회

0

다운로드

0

인용

0

참고문헌

주제분류이비인후과학

초록

Background and Objectives:We aimed to provide an updated data on the prevalence of allergic rhinitis (AR) in the Korean population and to evaluate the correlation between AR and hypertension, obesity, and smoking. Materials and Methods:Analysis of data from 31,822 people in Korean National Health and Nutrition Examination Survey during a 5-year period (from 2010 to 2014). The diagnosis of AR was done by questionnaire. Results:The overall prevalence of AR was 15.2% and 16.4% in Korean males and females, respectively. The prevalence tended to decrease with age. Subjects with AR were younger than those without (p<0.001) in both males and females. Living in urban area, history of atopic dermatitis, and asthma were all significantly correlated with higher prevalence (p<0.01). Risk for AR conferred to maternal hypertension history was 1.31 (95% CI=1.06-1.62 ; p<0.05) in the male population. However, systolic and diastolic blood pressures (DBP), medication history, and paternal hypertension history did not differ between the AR and normal groups (p>0.05). The odds ratio of obesity (BMI ≥25, compared to normal) for AR was 0.82 (95% CI=0.68-0.98 ; p<0.05) in the male population. Finally, the adjusted odds ratio of ex-smoker (compared to non-smoker) for AR was 1.41 (95% CI=1.05-1.89 ; p<0.05) in males. However, current smoking and pack-year did not differ between AR and normal groups (p>0.05). Conclusions:There was no significant correlation between hypertension and AR. In Korean adult males, obesity was associated with a low prevalence of allergic rhinitis. Although there was no significant correlation between current smoking and AR, there was a notable correlation between exsmoking and AR in male adults.

Abstract

Background and Objectives:We aimed to provide an updated data on the prevalence of allergic rhinitis (AR) in the Korean population and to evaluate the correlation between AR and hypertension, obesity, and smoking. Materials and Methods:Analysis of data from 31,822 people in Korean National Health and Nutrition Examination Survey during a 5-year period (from 2010 to 2014). The diagnosis of AR was done by questionnaire. Results:The overall prevalence of AR was 15.2% and 16.4% in Korean males and females, respectively. The prevalence tended to decrease with age. Subjects with AR were younger than those without (p<0.001) in both males and females. Living in urban area, history of atopic dermatitis, and asthma were all significantly correlated with higher prevalence (p<0.01). Risk for AR conferred to maternal hypertension history was 1.31 (95% CI=1.06-1.62 ; p<0.05) in the male population. However, systolic and diastolic blood pressures (DBP), medication history, and paternal hypertension history did not differ between the AR and normal groups (p>0.05). The odds ratio of obesity (BMI ≥25, compared to normal) for AR was 0.82 (95% CI=0.68-0.98 ; p<0.05) in the male population. Finally, the adjusted odds ratio of ex-smoker (compared to non-smoker) for AR was 1.41 (95% CI=1.05-1.89 ; p<0.05) in males. However, current smoking and pack-year did not differ between AR and normal groups (p>0.05). Conclusions:There was no significant correlation between hypertension and AR. In Korean adult males, obesity was associated with a low prevalence of allergic rhinitis. Although there was no significant correlation between current smoking and AR, there was a notable correlation between exsmoking and AR in male adults.

참고문헌 (27)

  1. 김지혜, "Detection of Allergen Specific Antibodies From Nasal Secretion of Allergic Rhinitis Patients", Allergy, Asthma & Immunology Research, 8(4), pp.329~337 (2016), 대한천식알레르기학회
  2. Salib RJ, "Allergic rhinitis: past, present and the future", Clin Otolaryngol Allied Sci, 28, pp.291~303 (2003)[DOI]
  3. Fineman SM, "The burden of allergic rhinitis: beyond dollars and cents", Ann Allergy Asthma Immunol Off Publ Am Coll Allergy Asthma Immunol, 88, pp.2~7 (2002)
  4. Ahn JC, "Prevalence and risk factors of chronic rhinosinusitus, alergic rhinitis, and nasal septal deviation: Results of the Korean National Health and Nutrition Survey 2008-2012", JAMA Otolaryngol- Head Neck Surg, 142, pp.162~167 (2016)[DOI]
  5. Brozek JL, "Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 revision", J Allergy Clin Immunol, 126, pp.466~476 (2010)[DOI]
  6. Kony S, "Rhinitis is associated with increased systolic blood pressure in men: a population-based study", Am J Respir Crit Care Med, 167, pp.538~543 (2003)[DOI]
  7. Aung T, "Allergic respiratory disease as a potential co-morbidity for hypertension", Cardiol J, 17, pp.443~447 (2010)
  8. Li C, "Hay fever and hypertension in the US adult population", Clin Exp Hypertens N Y N 1993, 36, pp.206~210 (2014)
  9. Heinrich J, "Blood pressure and rhinitis in adults: results of the MONICA", KORA-study, 2004, pp.22, 889~892
  10. Celebi Sozener Z, "Obesity-asthma phenotype: effect of weight gain on asthma control in adults", Allergy Asthma Proc Off J Reg State Allergy Soc, 37, pp.311~317 (2016)
  11. Bhatt NA, "Obesity-related asthma in adults", Postgrad Med, 128, pp.563~566 (2016)[DOI]
  12. Shin SH, "Comparison of Allergic Tests in Allergic Rhinitis and Bronchial Asthma Patients", J Clinical Otolaryngol, 8, pp.60~66 (1997)
  13. Lei Y, "Obesity is a risk factor for allergic rhinitis in children of Wuhan (China)", Asia Pac Allergy, 6, pp.101~104 (2016)[DOI]
  14. Han Y-Y, "Obesity and rhinitis in a nationwide study of children and adults in the United States", J Allergy Clin Immunol, 137, pp.1460~1465 (2016)[DOI]
  15. Loo EX-L, "Effects of infant weight gain on subsequent allergic outcomes in the first 3 years of life", BMC Pediatr, 17, pp.134~ (2017)[DOI]
  16. Iikuni N, "Leptin and Inflammation", Curr Immunol Rev, 4, pp.70~79 (2008)[DOI]
  17. Lord GM, "Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression", Nature, 394, pp.897~901 (1998)[DOI]
  18. Farooqi IS, "Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine", metabolic dysfunction of human congenital leptin deficiency, 2002, pp.110, 1093~1103
  19. Lannero E, "Exposure to environmental tobacco smoke and sensitisation in children", Thorax, 63, pp.172~176 (2008)
  20. Cakir E, "The prevalence and risk factors of asthma and allergic diseases among working adolescents", Asian Pac J Allergy Immunol Launched Allergy Immunol Soc Thail, 28, pp.122~129 (2010)
  21. Bendtsen P, "Alcohol consumption and the risk of selfreported perennial and seasonal allergic rhinitis in young adult women in a population-based cohort study", Clin Exp Allergy J Br Soc Allergy Clin Immunol, 38, pp.1179~1185 (2008)[DOI]
  22. Ludvigsson JF, "Exclusive breastfeeding and risk of atopic dermatitis in some 8300 infants", Pediatr Allergy Immunol Off Publ Eur Soc Pediatr Allergy Immunol, 16, pp.201~208 (2005)[DOI]
  23. Metsala J, "Maternal and perinatal characteristics and the risk of cow's milk allergy in infants up to 2 years of age: a case-control study nested in the Finnish population", Am J Epidemiol, 171, pp.1310~1316 (2010)[DOI]
  24. McKeever TM, "Siblings, multiple births, and the incidence of allergic disease: a birth cohort study using the West Midlands general practice research database", Thorax, 56, pp.758~762 (2001)[DOI]
  25. Wang I-J, "GSTM1, GSTP1, prenatal smoke exposure, and atopic dermatitis", Ann Allergy Asthma Immunol Off Publ Am Coll Allergy Asthma Immunol, 105, pp.124~129 (2010)
  26. Tariq SM, "The prevalence of and risk factors for atopy in early childhood: a whole population birth cohort study", J Allergy Clin Immunol, 101, pp.587~593 (1998)[DOI]
  27. Saulyte J, "Active or passive exposure to tobacco smoking and allergic rhinitis, allergic dermatitis, and food allergy in adults and children: a systematic review and meta-analysis", PLoS Med, 11, pp.e1001611~ (2014)[DOI]

관련 논문AI추천

비만과 알레르기 비염의 상관성에 관한 연구김솔리, 서운교, 신초영, 윤철호, 정혜미, 황민영한의병리학회 · 동의생리병리학회지2010 · 제24권 제6호Correlation between Metabolic Syndrome and Allergic Rhinitis이지숙, In Sik Kim, Min A Kim대한임상검사과학회 · 대한임상검사과학회지2019 · 제51권 제2호한국 성인에서 전자담배 흡연 경험과 알레르기비염 진단의 관계 – 2015 국민건강영양조사 자료 이용김만, 김선미, 김진욱, 윤소정, 윤정환, 이지영, 전혜란, 최윤선대한 소아알레르기 호흡기학회 · Allergy Asthma & Respiratory Disease2017 · 제5권 제6호한국 초·중·고등학생 알레르기비염의 전국 유병률과 위험 인자에 대한 분석이은, 강희태, 권지원, 김수영, 김수진, 김영호, 김유미, 김환철, 백영욱, 범은애, 사공준, 서주희, 손미아, 양송이, 오경재, 이기재, 이철갑, 임신예, 정해관, 조현주, 하미나, 홍수종대한 소아알레르기 호흡기학회 · Allergy Asthma & Respiratory Disease2015 · 제3권 제4호Assessing the Complex Impact of Smoking Habits on Allergic Rhinitis: A National Cross-Sectional Study김재형, 김태훈, 신재민, 이주현, 정유진대한이비인후과학회 · Clinical and Experimental Otorhinolaryngology2025 · 제18권 제1호한국 소아의 알레르기비염 역학김수영, 김양호, 김정희, 손병관, 양준모, 오인보, 이근화, 이지호, 이혜숙, 임대현, 정숙영, 홍성철, 황선혜대한 소아알레르기 호흡기학회 · Allergy Asthma & Respiratory Disease2013 · 제1권 제4호

이 간행물의 다른 논문 (22건)