신체질환을 앓고 있는 정신과환자에서의 정신약물의 사용 II -새로운 정신약물을 중심으로
Use of Psychotropic in Psychiatric Patient with Physical Disease II - Focus on Newer Psychotropics -
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초록
정신약물을 사용할 때 약물선택에 신중을 기해야 하 는 체중증가 및 비만, 당뇨, 간질을 앓고 있는 환자에서 의 정신약물의 사용에 대하여 상기와 같이 고찰하였다. 상기의 신체질환이 있는 환자에게 정신약물을 사용 하는 경우에 약물의 선택 및 용량조절, 부작용 및 이와 관련된 문제 등을 필히 고려해야만 한다. 특히 상기 신 체질환 환자에서의 정신약물의 사용은 정신약물 사용 자체가 병의 발생 및 경과에 영향을 미칠 수 있으므로 약물 선택과 사용에 주의를 요하고 있다. 이에 본 논문은 지난 논문에서 다루지 않았던 상기 신체질환을 가진 환자들에게 정신약물을 사용할 경우 관심을 가져야 하는 약물을 중심으로 고찰하였다. 신체 질환 환자에서 정신약물 사용 시 더욱 주의를 기울여야 할 점을 숙지함으로써 더욱 향상된 치료를 시행할 수 있 을 것이다.
Abstract
The author reviewed the considerable factors of using psychotropic agents(antipsychotics, antidepressants, anti¬anxiety and hypnotics, mood stabilizers, and other psychotropics) in psychiatric patients with physical disease, es¬pecially weight gain and obesity, diabetes, and epilepsy. Because of the increasing risk of obesity, diabetes, and seizure related to decrease of seizure threshold by psychotropics, psychiatrists have to use psychotropics more carefully. It will be more helpful to treat psychiatric patients with physical disease.
참고문헌 (180)
- 이경규, "신체질환을 앓고 있는 정신과환자에서의 정신약물의 사용", 생물치료정신의학, 13(2), pp.158~169 (2007), 대한생물치료정신의학회
- Ackerman S, "Bodyweight Gain Induced by Psychotropic Drugs: Incidence, Mechanisms and Management", CNS Drugs, 9, pp.135~151 (1998)
- Keck PE, "Bipolar Disorder, Obesity, and Pharmacotherapy-Associated Weight Gain", J Clin Psychiatry, 64, pp.1426~1435 (2003)
- McElroy SL, "Are Mood Disorders and Obesity Related? A Review for the Mental Health Professional", J Clin Psychiatry, 65, pp.634~651 (2004)
- Schwartz TL, "Psychiatric medication-induced obesity: a review", Obes Rev, 5, pp.115~121 (2004)
- Vanina Y, "Body Weight Changes Associated With Psychopharmacology", Psychiatr Serv, 53, pp.842~847 (2002)
- Allison DB, "The Distribution of Body Mass Index Among Individuals With and Without Schizophrenia", J Clin Psychiatry, 60, pp.215~220 (1999)
- Baptista T, "Body weight gain induced by antipsychotic drugs: mechanisms and management", Acta Psychiatr Scand, 100, pp.3~16 (1999)
- Sechter D, "the Amisulpride Study Group. Amisulpride vs. Risperidone in Chronic Schizophrenia: Results of a 6- month. Double-blind Study", Neuropsychopharmacology, 27, pp.1071~1081 (2002)
- Mahe V, "Lack of weight gain during amisulpride treatment", Eur Neuropsychopharmacol, 11(Suppl 4), pp.S292~ (2001)
- Kolotkin RL, "Changes in weight and weight-related quality of life in a multicentre, randomized trial of aripiprazole versus standard of care" (2008), Eur Psychiatry In press, Corrected Proof
- Kerwin R, "A multicentre, randomized, naturalistic, open-label study between aripiprazole and standard of care in the management of community-treated schizophrenic patients Schizophrenia Trial of Aripiprazole: (STAR) study", Eur Psychiatry, 22, pp.433~443 (2007)
- Lamberti S, "Weight gain among schizophrenic patients treated with clozapine", Am J Psychiatry, 149, pp.689~690 (1992)
- Meyer JM, "Change in metabolic syndrome parameters with antipsychotic treatment in the CATIE Schizophrenia Trial: Prospective data from phase 1", Schizophr Res, 101, pp.273~286 (2008)
- Gupta S, "Olanzapine: weight gain and therapeutic efficacy", J Clin Psychopharmacology, 19, pp.273~274 (1999)
- Tran P, "Double blind comparison of olanzapine versus risperidone in the treatment of schizophrenia and other psychotic disorders", J Clin Psychopharmacology, 17, pp.407~418 (1997)
- Perez-Iglesias R, "Weight gain induced by haloperidol, risperidone and olanzapine after 1 year: Findings of a randomized clinical trial in a drug-naive population", Schizophr Res, 99, pp.13~22 (2008)
- Marder SR, "Efficacy and Safety of Paliperidone Extended-Release Tablets: Results of a 6-Week, Randomized, Placebo-Controlled Study", Biol Psychiatry, 62, pp.1363~1370 (2007)
- Arvanitis LA, "Multiple fixed doses of “Seroquel”(Quetiapine) in patients with acute exacerbation of schizophrenia: a comparison with haloperidol and placebo", Biol Psychiatry, 42, pp.233~236 (1997)
- Adler CM, "Safety and tolerability of quetiapine in the treatment of acute mania in bipolar disorder", J Affect Disord, 100(Suppl 1), pp.S15~S22 (2007)
- Gunasekara NS, "A review of its use in schizophrenia", CNS Drugs, 9, pp.325~340 (1998)
- Ganguli R, "Weight gain over 4 months in schizophrenia patients: a comparison of olanzapine and risperidone", Schizophr Res, 49, pp.261~267 (2001)
- Peuskens J, "Risperidone in the treatment of patients with chronic schizophrenia: a multi-national, multicentered, double-blind, parallel-group study versus haloperidol", Br J Psychiatry, 166, pp.712~733 (1995)
- Wirshing D, "Novel antipsychotics: weight gain liabilities", J Clin Psychiatry, 60, pp.358~363 (1999)
- Taylor DM, "Atypical antipsychotics and weight gain- a systematic review", Acta Psychiatr Scand, 101, pp.416~432 (2000)
- Ratner Y, "Effectiveness, safety, and tolerability of ziprasidone for treating schizophrenia patients undergoing usual care: A 12- month, open-label, flexible-dose, naturalistic observational trial", Prog Neuropsychopharmacol Biol Psychiatry, 31, pp.1401~1409 (2007)
- Lin WW, "Clinical efficacy, body weight change and cardiac safety of zotepine in schizophrenic patients", Eur Neuropsychopharmacol, 16(Suppl 4), pp.S415~S416 (2006)
- Allison DB, "Antipsychotic-induced weight gain: a comprehensive research synthesis", Am J Psychiatry, 156, pp.1686~1696 (1999)
- Adams CE, "Chlorpromazine versus placebo for schizophrenia", Cochrane Database Syst Rev, 18 (2007)
- Bernstein J, "Psychotropic drug induced weight gain: mechanism and management", Clin Neuropharmacol, 11, pp.194~206 (1988)
- Fava M, "Weight gain and antidepressants", J Clin Psychiatry, 61(Suppl 11), pp.S37~S41 (2000)
- Aronne LJ, "Weight gain in the treatment of mood disorders", J Clin Psychiatry, 64(Suppl 8), pp.S22~S29 (2003)
- Kraus T, "Body weight, the tumor necrosis factor system and leptin production during treatment with mirtazapine or venlafaxine", Pharmacopsychiatry, 35, pp.220~225 (2002)
- Silverstone PH, "Once-daily venlafaxine extended release(XR) compared with fluoxetine in outpatients with depression and anxiety", J Clin Psychiatry, 60, pp.22~28 (1999)
- Raskin J, "Duloxetine in the long-term treatment of major depressive disorder", J Clin Psychiatry, 64, pp.1237~1244 (2003)
- Perahia DGS, "Duloxetine in the treatment of major depressive disorder: a placebo- and paroxetine-controlled trial", Eur Psychiatry, 21, pp.367~378 (2006)
- Zimmermann U, "Epidemiology, implications and mechanisms underlying drug-induced weight gain in psychiatric patients", J Psychiatr Res, 37, pp.193~220 (2003)
- Montgomery SA, "A 24-Week Randomized, Double-Blind, Placebo- Controlled Study of Escitalopram for the Prevention of Generalized Social Anxiety Disorder", J Clin Psychiatry, 66, pp.1270~1278 (2005)
- Michelson D, "Changes in weight during a 1-year trial of fluoxetine", Am J Psychiatry, 156, pp.1170~1176 (1999)
- Abell CA, "Placebo controlled double-blind trial of fluvoxamine maleate in the obese", J Psychosom Res, 30, pp.143~146 (1986)
- Hinze-Selch D, "Effects of antidepressants on weight and on the plasma levels of leptin, TNF and soluble TNF receptors: a longitudinal study in patients treated with amitriptyline or paroxetine", Neuropsychopharmacology, 23, pp.13~19 (2000)
- Fava M, "Fluoxetine versus sertraline and paroxetine in major depressive disorder: changes in weight with long-term treatment", J Clin Psychiatry, 61, pp.863~867 (2000)
- Fernstrom MH, "Resting metabolic rate is reduced in patients treated with antidepressants", Biol Psychiatry, 20, pp.692~695 (1985)
- Fernstrom MH, "Drugs that cause weight gain", Obesity Research, 3(Suppl 4), pp.S435~S439 (1995)
- Croft H, "Effect on body weight of bupropion sustained-release in patients with major depression treated for 52 weeks", Clin Ther, 24, pp.662~672 (2002)
- Gadde KM, "Bupropion for weight loss: An investigation of efficacy and tolerability in overweight and obese women", Obesity Research, 9, pp.544~551 (2001)
- Fawcett J, "Review of the results from clinical studies on the efficacy, safety and tolerability of mirtazapine for the treatment of patients with major depression", J Affect Disord, 51, pp.267~285 (1998)
- Sussman N, "Weight effects of nefazodone, bupropion, mirtazapine, and venlafaxine: A review of the available evidence", Primary Psychiatry, 7, pp.33~48 (2000)
- Zimmermann U, "Effect of naltrexone on weight gain and food craving induced by tricyclic antidepressants and lithium: an open study", Biol Psychiatry, 41, pp.747~749 (1997)
- Fagiolini A, "Prevalence of Obesity and Weight Change During Treatment in Patients With Bipolar I Disorder", J Clin Psychiatry, 63, pp.528~533 (2002)
- Schou M, "Pharmacological and clinical problems of lithium prophylaxis", Br J Psych, 116, pp.615~619 (1970)
- Vendsborg PB, "Lithium treatment and weight gain", Acta Psych Scand, 53, pp.139~147 (1976)
- Vestergaard P, "Prospective studies on a lithium cohort 3: tremor, weight gain, diarrhea, psychological complaints", Acta Psych Scand, 78, pp.434~441 (1988)
- Atmaca M, "Weight gain and serum leptin levels in patients on lithium treat ment", Neuropsychobiology, 46, pp.67~69 (2002)
- Mathew B, "Lithium-induced changes in the body mass index", Acta Psych Scand, 80, pp.538~540 (1989)
- Baptista T, "Lithium and body weight gain", Pharmacopsychiatry, 28, pp.35~44 (1995)
- Nasrallah A, "Carbamazepine and valproate for the treatment of bipolar disorder: a review of the literature", J Affect Disord, 95, pp.69~78 (2006)
- Chengappa KNR, "Changes in body weight and body mass index among psychiatric patients receiving lithium, valproate, or topiramate: An open-label, nonrandomized chart review", Clin Ther, 24, pp.1576~1584 (2002)
- Davis R, "Valproic acid: a reappraisal of its pharmacological properties and clinical efficacy in epilepsy", Drugs, 47, pp.332~342 (1994)
- Sussman N, "Effect of psychotropic drugs on weight", Psychiatric Annals, 29, pp.580~594 (1999)
- Verrotti A, "Serum leptin changes in epileptic patients who gain weight after therapy with Valproic acid", Neurology, 53, pp.230~232 (1999)
- DeToledo JC, "Changes in body weight with chronic, high dose gabapentin therapy", Ther Drug Monit, 19, pp.394~396 (1997)
- Hogan RE, "Total percentage body weight changes during addon therapy with tiagabine, carbamazepine and phenytoin", Epilepsy Res, 41, pp.23~28 (2000)
- David Chadwick and for the Vigabatrin European Monotherapy Study Group, "Safety and efficacy of vigabatrin and carbamazepine in newly diagnosed epilepsy: a multicentre randomised double-blind study", Lancet, 354, pp.13~19 (1999)
- Calabrese JR, "A double-blind, placebocontrolled, prophylaxis study of lamotrigine in rapidcycling bipolar disorder", J Clin Psychiatry, 61, pp.841~850 (2000)
- Rosenfeld W, "Weight loss patterns with topiramate therapy", Epilepsia, 38, pp.60~63 (1997)
- Gordon A, "Mood stabilization and weight loss with topiramate", Am J Psychiatry, 156, pp.968~969 (1999)
- Evans S, "Food “craving” and the acute effect of alprazolam on food intake in women with premenstrual dysphoric disorder", Appetite, 32, pp.331~349 (1999)
- Physicians’ Desk Reference, "Montvale" (2000), NJ: Medical Economics Data Production Company
- Vanina Y, "Body Weight Changes Associated With Psychopharmacology", Psychiatr Serv, 53, pp.842~847 (2002)
- Dixon L, "Prevalence and correlates of diabetes in national schizophrenia samples", Schizophr Bull, 26, pp.903~912 (2000)
- Bushe C, "Prevalence of diabetes and impaired glucose tolerance in patients with schizophrenia", Br J Psychiatry, 47(Supp l), pp.S67~71 (2004)
- Haddad PM, "Antipsychotics and diabetes: review of non-prospective data", Br J Psychiatry, 47(Suppl), pp.S80~S86 (2004)
- Kohen D, "Diabetes mellitus and schizophrenia: historical perspective", Br J Psychiatry, 47(Supp l), pp.S64~S66 (2004)
- Ryan MC, "Impaired fasting glucose tolerance in first-episode, drug-naive patients with schizophrenia", Am J Psychiatry, 160, pp.284~289 (2003)
- Lindenmeyer JP, "Changes in glucose and cholesterol levels in patients with schizophrenia treat-ed with typical or atypical antipsychotics", Am J Psy-chiatry, 160, pp.290~296 (2003)
- Lieberman JA, "Effectiveness of antipsychotic drugs in patients with chronic schizophrenia", N Engl J Med, 353, pp.1209~1223 (2005)
- Singh R, "Mental health, antipsychotics and hyperglycaemia", Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 1, pp.209~224 (2007)
- Haupt DW, "Differential metabolic effects of antipsychotic treatments", Eur Neuropsychopharmacol, 16(Suppl 3), pp.S149~S155 (2006)
- De Hert MA, "Prevalence of the metabolic syndrome in patients with schizophrenia treated with antipsychotic medication", Schizophr Res, 83, pp.87~93 (2006)
- Pigott TA, "Aripiparzole for the prevention of relapse in stabilized patients with chronic schizophrenia: a placebo-controlled 26-week study", J Clin Psychiatry, 64, pp.1048~1056 (2003)
- Lund BC, "Clozapine use in patients with schizophrenia and the risk of diabetes, hyperlipidemia, and hypertension: a claimsbased approach", Arch Gen Psychiatry, 58, pp.1172~1176 (2001)
- Sernyak MJ, "Association of diabetes mellitus with use of atypical neuroleptics in the treatment of schizophrenia", Am J Psychiatry, 159, pp.561~566 (2002)
- Gianfrancesco F, "Antipsychotic-induced type 2 diabetes: evidence from a large health plan database", J Clin Psychopharmacol, 23, pp.328~335 (2003)
- Wirshing DA, "Risperidone-associated new-onset diabetes", Biol Psychiatry, 50, pp.148~149 (2001)
- Citrome L, "Relationship between antipsychotic medication treatment and new cases of diabetes among psychiatric inpatients", Psychiatr Serv, 55, pp.1006~1013 (2004)
- Kane J, "Treatment of schizophrenia with paliperidone extended-release tablets: A 6-week placebo- controlled trial", Schizophr Res, 90, pp.147~161 (2007)
- Mallya A, "Resolution of hyperglycemia on risperidone discontinuation; a case report", J Clin Psychiatry, 63, pp.453~454 (2002)
- Wilson DR, "New-onset diabetes and ketoacidosis with atypical antipsychotics", Schizophr Res, 59, pp.1~6 (2003)
- Koller EA, "Risperidone-associated diabetes mellitus: a pharmacovigilance study", Pharmacotherapy, 23, pp.735~744 (2003)
- Newcomer JW, "Abnormalities in glucose regulation during antipsychotic treatment of schizophrenia", Arch Gen Psychiatry, 59, pp.337~345 (2002)
- Simpson GM, "Randomized, controlled, double-blind multicenter comparison of the efficacy and tolerability of ziprasidone and olanzapine in acutely ill inpatients with schizophrenia or schizoaffective disorder", Am J Psychiatry, 161, pp.1837~1847 (2004)
- Kudla D, "Effectiveness, tolerability, and safety of ziprasidone in patients with schizophrenia or schizoaffective disorder: Results of a multi-centre observational trial", Eur Psychiatry, 22, pp.195~202 (2007)
- Newcomer JW, "Second-generation(atypical) antipsychotics and metabolic effects: a comprehensive literature review", CNS Drugs, 19(Suppl 1), pp.S1~S93 (2005)
- Schwarz L, "Blood Sugar Levels in Patients Treated with Chlorpromazine", Am J Psychiatry, 125, pp.253~255 (1968)
- Musselmana DL, "Relationship of depression to diabetes types 1 and 2: epidemiology, biology, and treatment", Biol Psychiatry, 54, pp.317~329 (2003)
- Anderson RJ, "Lustman PJ. The prevalence of comorbid depression in adults with diabetes: a meta-analysis", Diabetes Care, 24, pp.1069~1078 (2001)
- Eaton WW, "Depression and risk for onset of type II diabetes. A prospective population-based study", Diabetes Care, 19, pp.1097~1102 (1996)
- Bisschop MI, "The longitudinal relation between chronic diseases and depression in older persons in the community: the Longitudinal Aging Study Amsterdam", J Clin Epidemiol, 57, pp.187~194 (2004)
- Lustman PJ, "Depression and poor glycemic control: a meta-analytic review of the literature", Diabetes Care, 23, pp.934~942 (2000)
- Lin EH, "Effects of enhanced depression treatment on diabetes self-care", Ann Fam Med, 4, pp.46~53 (2006)
- Rubin RR, "Depression symptoms and antidepressant medicine use in Diabetes Prevention Program participants", Diabetes Care, 28, pp.830~837 (2005)
- McIntyre RS, "The effect of antidepressants on glucose homeostasis and insulin sensitivity: synthesis and mechanism", Expert Opin Drug Saf, 5, pp.157~168 (2006)
- Kajdasz DK, "Duloxetine for the Management of Diabetic Peripheral Neuropathic Pain: Evidence- Based Findings from Post Hoc Analysis of Three Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Studies", Clin Ther, 29, pp.2536~2546 (2007)
- Maheux P, "Fluoxetine improves insulin sensitivity in obese patients with non-insulin-dependent diabetes mellitus independently of weight loss", Int J Obes Relat Metab Disord, 21, pp.97~102 (1997)
- Gray DS, "A randomized double-blind clinical trial of fluoxetine in obese diabetics", Int J Obes Relat Metab Disord, 16(Suppl 4), pp.S67~S72 (1992)
- Sindrup SH, "The selective serotonin reuptake inhibitor citalopram relieves the symptoms of diabetic neuropathy", Clin Pharmacol Ther, 52, pp.547~552 (1992)
- Oswald P, "Fluvoxamine-induced hyperglycaemia in a diabetic patient with comorbid depression", Int J Neuropsychopharmacol, 6, pp.85~87 (2003)
- Gu¨ lseren L, "Comparison of fluoxetine and paroxetine in type II diabetes mellitus patients", Arch Med Res, 36, pp.159~165 (2005)
- Lustman PJ, "Sertraline for prevention of depression recurrence in diabetes mellius: a randomized, double-blind, placebo-controlled trial", Arch Gen Psychiatry, 63, pp.521~529 (2006)
- Brown LC, "Type of antidepressant therapy and risk of type 2 diabetes in people with depression", Diabetes Res Clini Prac, 79, pp.61~67 (2008)
- Lustman PJ, "Factors influencing glycemic control in type 2 diabetes during acute- and maintenance-phase treatment of major depressive disorder with bupropion", Diabetes Care, 30, pp.459~466 (2007)
- Himmerich H, "Changes in weight and glucose tolerance during treatment with mirtazapine", Diabetes Care, 29, pp.170~ (2006)
- Amrein R, "Schmid-Burgk W. Interactions of moclobemide with concomitantly administered medication: evidence from pharmacological and clinical studies", Psychopharmacology( Berl), 106(Suppl), pp.S24~S31 (1992)
- Dosterta P, "Review of the pharmacokinetics and metabolism of reboxetine, a selective noradrenaline reuptake inhibitor", Eur Neuropsychopharmacol, 7(Suppl 1), pp.S23~S35 (1997)
- Taylor D, "The Maudsley Prescribing Guidelines, 9th ed" (2007), London and New York: Informa Healthcare
- Ketter TA, "Mood stabilizers and atypical antipsychotics: bimodal treatments for bipolar disorder", Psychopharmacol Bull, 39, pp.120~146 (2006)
- Stefan H, "Novel anticonvulsant drugs", Pharmacol Ther, 113, pp.165~183 (2007)
- Doucet J, "Protein binding of digitoxin, valproate and phenytoin in sera from diabetics", Eur J Clin Pharmacol, 45, pp.577~579 (1993)
- Schnabel T Jr, "Evaluation of the safety and side effects of antianxiety agents", Am J Medicine, 82(Suppl 1), pp.7~13 (1987)
- Wagner J, "Non-benzodiazepines for the treatment of insomnia", Sleep Med Rev, 4, pp.551~581 (2000)
- Kerr D, "Betaadrenoceptor blockade and hypoglycaemia. A randomised, double-blind, placebo controlled comparison of metoprolol CR, atenolol and propranolol LA in normal subjects", Br J Clin Pharmacol, 29, pp.685~693 (1990)
- Bazire S, "Psychotropic drug directory 2005", pp.217~218 (2005), Salisbury: Fivepin
- Harden CL, "Mood disorders in patients with epilepsy: epidemiology and management", CNS Drugs, 16, pp.291~302 (2002)
- Lambert MV, "Depression in epilepsy: etiology, phenomenology, and treatment", Epilepsia, 409(Suppl 10), pp.S21~S47 (1999)
- Blumer D, "Treatment of the interictal psychoses", J Clin Psychiatry, 61, pp.110~122 (2000)
- Pisani F, "Effects of psychotropic drugs on seizure threshold", Drug Saf, 25, pp.91~110 (2002)
- Stimmen GL, "Psychotropic druginduced reductions in seizure threshold: Incidence and consequences", CNS Drugs, 5, pp.37~50 (1996)
- Jobe PC, "The serotonergic and noradrenergic effects of antidepressant drugs are anticonvulsant, not proconvulsant", Epilepsy Behav, 7, pp.602~619 (2005)
- Marks RC, "Antipsychotic medications and seizures", Psychiatr Med, 9, pp.37~52 (1991)
- Hedges D, "Antipsychotic medication and seizures: a review", Drugs Today(Barc), 39, pp.551~557 (2003)
- Tracqui A, "Amisulpride poisoning: a report on two cases", Hum Exp Toxicol, 14, pp.294~298 (1995)
- Tsai JF, "Aripiprazole-associated seizure", J Clin Psychiatry, 67, pp.995~996 (2006)
- Malik AR, "Aripiprazole-induced seizure", Can J Psychiatry, 50, pp.186~ (2005)
- Pacia SV, "Clozapine-related seizures: Exprerience with 5,629 patients", Neurology, 44, pp.2247~2249 (1994)
- Dedges DW, "Antipsychotic medication and seizures: A review", Drugs Today(Barc), 39, pp.437~439 (2002)
- Naber D, "Efficacy and adverse effects of clozapine in the treatment of schizophrenia and tardive dyskinesia-a retrospective study of 387 patients", Psychopharmacology (Berl), 99(Suppl), pp.S73~S76 (1989)
- Treves IA, "EEG abnormalities in clozapine- treated schizophrenic patients", Eur Neuropsychopharmacol, 6, pp.93~94 (1996)
- Popli AP, "Valproate and force control during clozapine treatment in schizophrenic patients", Schizophr Res, 24, pp.216~ (1997)
- Amann BL, "EEG abnormalities associated with antipsychotics: a comparison of quetiapine, olanzapine, haloperidol and healthy subjects", Hum Psychopharmacol, 18, pp.641~646 (2003)
- Pillmann F, "Electroencephalogram alterations during treatment with olanzapine", Psychopharmacology(Berl), 150, pp.216~219 (2000)
- Lee KC, "Risk of seizures associated with psychotropic medications: Emphasis on new drugs and new findings", Expert Opin Drug Saf, 2, pp.233~247 (2003)
- Woolley J, "Lowered seizure threshold on olanzapine", Br J Psychiatry, 178, pp.85~86 (2001)
- Dogu O, "Seizures associated with quetiapine treatment", Ann Pharmacother, 37, pp.1224~1227 (2003)
- Hedges DW, "New-onset seizure associated with quetiapine and olanzapine", Ann Pharmacother, 36, pp.437~439 (2002)
- Janssen Pharmaceuticals, (2007), New Jersey: Janssen Pharmaceuticals
- Janssen Pharmaceuticals, (2007), New Jersey: Janssen Pharmaceuticals
- Alldredge BK, "Seizure risk associated with psychotropic drugs: clinical and pharmacokinetic considerations", Neurology, 53(Suppl 2), pp.S68~S75 (1999)
- "New York: Pfizer Inc", 2007, ~
- Hori M, "Convulsive seizures in schizophrenic patients induced by zotepine administration", Jpn J Psychiatry Neurol, 46, pp.161~167 (1992)
- Markowitz JC, "Seizures with neuroleptics and antidepressants", Gen Hosp Psychiatry, 9, pp.135~141 (1987)
- Borowicz KK, "Fluoxetine enhances the anticonvulsant effects of conventional antiepileptic drugs in maximal electroshock seizures in mice", Pharmacol Rep, 58, pp.83~90 (2006)
- Pericic D, "Anticonvulsant effects of acute and repeated fluoxetine treatment in unstressed and stressed mice", Brain Res, 1033, pp.90~95 (2005)
- Cuenca PJ, "Seizure secondary to citalopram overdose", J Emerg Med, 26, pp.177~181 (2004)
- Kelly CA, "Comparative toxicity of citalopram and the newer antidepressants after overdose", J Toxicol Clin Toxicol, 42, pp.67~1 (2004)
- Clinckers R, "In vivo modulatory action of extracellular glutamate on the anticonvulsant effects of hippocampal dopamine and serotonin", Epilepsia, 46, pp.828~836 (2005)
- Pisani F, "Antidepressant drugs and seizure susceptibility: From in vitro data to clinical practice", Epilepsia, 40(Suppl 10), pp.S48~S56 (1999)
- White CM, "Seizure resulting from a venlafaxine overdose", Ann Pharmacother, 32, pp.135~136 (1998)
- Maramattom V, "Duloxetine-induced syndrome of inappropriate antidiuretic hormone secretion and seizures", Neurology, 66, pp.773~774 (2006)
- Alper K, "Seizure Incidence in Psychopharmacological Clinical Trials: An Analysis of Food and Drug Administration(FDA) Summary Basis of Approval Reports", Biol Psychiatry, 62, pp.345~354 (2007)
- Curran S, "Selecting an Antidepressant for Use in a Patient with Epilepsy: Safety Considerations", Drug Saf, 18, pp.125~133 (1998)
- Mongomery SA, "Antidepressants and seizures: emphasis on newer agents and clinical implications", Int J Clin Pract, 59, pp.1435~1440 (2005)
- Preskorn SH, "Tricyclic antidepressant-indu ced seizures and plasma drug concentration", J Clin Psychiatry, 54, pp.201~202 (1993)
- Rosenstein DL, "Seizures associated with antidepressants: A review", J Clin Psychiatry, 54, pp.289~299 (1993)
- Davidson J, "Seizures and bupropion: A review", J Clin Psychiatry, 50, pp.256~261 (1989)
- Jefferson JW, "Bupropion for major depressive disorder: Pharmacokinetic and formulation considerations", Clin Ther, 27, pp.1685~1695 (2005)
- Tutka P, "Convulsant and anticonvulsant effects of bupropion in mice", Eur J Pharmacol, 499, pp.117~120 (2004)
- Juckel G, "Epileptiform EEG Patterns Induced by Mirtazapine in Both Psychiatric Patients and Healthy Volunteers", J Clin Psychopharmacol, 23, pp.421~422 (2003)
- Haq MZU, "Mirtazapine precipitated seizures: A case report", Prog Neuropsychopharmacol Biol Psychiatry, 32, pp.1076~1078 (2008)
- Schiwy W, "Therapeutic and side-effect profile of a selective and reversible MAOA inhibitor, brofaromine. Results of dose-finding trials in depressed patients", J Neural Transm Suppl, 28, pp.33~44 (1989)
- Ku¨ hn K, "Antidepressive treatment in patients with temporal lobe epilepsy and major depression: a prospective study with three different antidepressants", Epilepsy Behav, 4, pp.674~679 (2003)
- "Electronic Medicines Compendium"[URL]
- Miyamoto T, "Psychotic episodes during zonisamide treatment", Seizure, 9, pp.65~70 (2000)
- Besag FM, "Behavioural effects of the newer antiepileptic drugs: an update", Expert Opin Drug Saf, 3, pp.1~8 (2004)
- Sillanpa¨ a¨ M, "Prognosis of seizure recurrence after stopping antiepileptic drugs in seizure-free patients: A long-term population-based study of childhood- onset epilepsy", Epilepsy Behav, 8, pp.713~719 (2006)
- Britton JW, "Antiepileptic drug withdrawal: literature review", Mayo Clin Proc, 77, pp.1378~1388 (2002)
- Browne JL, "A review of alprazolam withdrawal", Drug Intell Clin Pharm, 20, pp.837~841 (1986)
- Catalano G, "Seizures associated with buspirone overdose: case report and literature review", Clin Neuropharmacol, 21, pp.347~350 (1998)
- Julou L, "Pharmacological and clinical studies of cyclopyrrolones: zopiclone and suriclone", Pharmacol Biochem Behav, 23, pp.653~659 (1985)
- McConchie RD, "Disulfiram- induced de novo seizures in the absence of ethanol challenge", J Stud Alcohol, 44, pp.739~743 (1983)
