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Light-Microscopy-Based Sparse Neural Circuit Reconstruction: Array Tomography and Other Methods

라종철
한국현미경학회 (Korean Society Of Microscopy)|2016.12|Applied Microscopy|제46권 제4호|pp. 176-178

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참고문헌

키워드

Light microscopyArray tomographyNeural circuit reconstruction
주제분류자연과학일반

초록

Efficient neural circuit reconstruction requires sufficient lateral and axial resolution to resolve individual synapses and map a large enough volume of brain tissue to reveal the molecular identity and origin of these synapses. Sparse circuit reconstruction using array tomography meets many of these requirements but also has some limitations. In this minireview, the advantages and disadvantages of applicable imaging techniques will be discussed.

Abstract

Efficient neural circuit reconstruction requires sufficient lateral and axial resolution to resolve individual synapses and map a large enough volume of brain tissue to reveal the molecular identity and origin of these synapses. Sparse circuit reconstruction using array tomography meets many of these requirements but also has some limitations. In this minireview, the advantages and disadvantages of applicable imaging techniques will be discussed.

참고문헌 (25)

  1. Bloss E B, "Structured dendritic inhibition supports branch- selective integration in CA1 pyramidal cells", Aeuron, 89, pp.1016~1030 (2016)
  2. Bock D D, "Network anatomy and in vivo physiology of visual cortical neurons", Nature, 471, pp.177~182 (2011)
  3. Briggman K L, "Wiring specificity in the direction-selectivity circuit of the retina", Nature, 471, pp.183~188 (2011)
  4. Cella Zanacchi F, "Live-cell 3D super-resolution imaging in thick biological samples", Nat. Meth, 8, pp.1047~1049 (2011)
  5. Chen F, "Optical imaging. Expansion microscopy", Science, 347, pp.543~548 (2015)
  6. Chen F, "Nanoscale imaging of RNA with expansion microscopy", Nature Methods, 13, pp.679~684 (2016)
  7. DeFelipe J, "Estimation of the number of synapses in the cerebral cortex: methodological considerations", Cerebral Cortex, 9, pp.722~732 (1999)
  8. Feinberg E H, "GFP reconstitution across synaptic partners (GRASP) defines cell contacts and synapses in living nervous systems", Neuron, 57, pp.353~363 (2008)
  9. Graf E R, "Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins", Cell, 119, pp.1013~1026 (2004)
  10. Hayworth K J, "Automating the collection of ultrathin serial sections for large volume TEM reconstructions", Microsc. Microanal, 12, pp.86~87 (2006)
  11. Huang B, "Three-dimensional super-resolution imaging by stochastic optical reconstruction microscopy", Science, 319, pp.810~813 (2008)
  12. Kim J, "mGRASP enables mapping mammalian synaptic connectivity with light microscopy", Nat. Meth, 9, pp.96~102 (2011)
  13. Lee W C A, "Anatomy and function of an excitatory network in the visual cortex", Nature, 532, pp.370~374 (2016)
  14. Micheva K D, "Single-synapse analysis of a diverse synapse population: proteomic imaging methods and markers", Neuron, 68, pp.639~653 (2010)
  15. Micheva K D, "Array tomography: a new tool for imaging the molecular architecture and ultrastructure of neural circuits", Neuron, 55, pp.25~36 (2007)
  16. Mikula S, "Staining and embedding the whole mouse brain for electron microscopy", Nat. Meth, 9, pp.1198~1201 (2012)
  17. Mishchenko Y, "On optical detection of densely labeled synapses in neuropil and mapping connectivity with combinatorially multiplexed fluorescent synaptic markers", PLoS One, 5, pp.e8853~ (2010)
  18. Morgan J L, "The fuzzy logic of network connectivity in mouse visual thalamus", Cell, 165, pp.192~206 (2016)
  19. Nanguneri S, "Three-dimensional, tomographic super-resolution fluorescence imaging of serially sectioned thick samples", PLoS One, 7, pp.e38098~ (2012)
  20. Punge A, "3D reconstruction of high-resolution STED microscope images", Microsc. Res. Tech, 71, pp.644~650 (2008)
  21. Rah J C, "Thalamocortical input onto layer 5 pyramidal neurons measured using quantitative large-scale array tomography", Front. Neural Circuits, 7, pp.177~ (2013)
  22. Scheiffele P, "Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons", Cell, 101, pp.657~669 (2000)
  23. Shtengel G, "Interferometric fluorescent superresolution microscopy resolves 3D cellular ultrastructure", Proc. Natl. Acad. Sci. U.S.A, 106, pp.3125~3130 (2009)
  24. Sigal Y M, "Mapping synaptic input fields of neurons with super-resolution imaging", Cell, 163, pp.493~505 (2015)
  25. Tomer R, "SPED light sheet microscopy: fast mapping of biological system structure and function", Cell, 163, pp.1796~1806 (2015)

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