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Cryo-Transmission Electron Microscopy in Korean Society of Microscopy

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초록

Dr. Jacques Dubochet, Dr. Joachim Frank, and Dr. Richard Henderson received the 2017 Nobel Prize for Chemistry for their efforts to develop effective ways to obtain highresolution three-dimensional images of biomolecules using cryo-electron microscopy. Congratulations to the Nobel Prize in the field of electron microscopy, I will explain the scientific contributions of the three winners and introduce the role of cryo-electron microscopy (including cryo technology) in biology.

Abstract

Dr. Jacques Dubochet, Dr. Joachim Frank, and Dr. Richard Henderson received the 2017 Nobel Prize for Chemistry for their efforts to develop effective ways to obtain highresolution three-dimensional images of biomolecules using cryo-electron microscopy. Congratulations to the Nobel Prize in the field of electron microscopy, I will explain the scientific contributions of the three winners and introduce the role of cryo-electron microscopy (including cryo technology) in biology.

참고문헌 (10)

  1. Cavalier A, "Handbook of Cryo-Preparation Methods for Electron Microscopy" (2008), CRC Press
  2. Dubochet J, "Cryo-electron microscopy of vitrified specimens", Quart. Rev. Biophys, 21, pp.129~228 (1988)
  3. Dubochet J, "Electron microscopy of frozen water and aqueous solutions", J. Microsc, 128, pp.219~237 (1982)
  4. Dubochet J, "Vitrification of pure water for electron microscopy", J. Microsc, 124, pp.3~4 (1981)
  5. Frank J, "Averaging of low exposure electron micrographs of nonperiodic objects", Ultramicroscopy, 1, pp.159~162 (1975)
  6. Frank J, "In Three-Dimensional Electron Microscopy of Macromolecular Assemblies", pp.15~17 (1996), Academic Press
  7. Frank J, "Electron Tomography, Methods for Three-Dimensional Visualization of Structure in the Cell" (2005), Springer
  8. Frank J, "Three-Dimensional Electron Microscopy of Macromolecular Assemblies: Visualization of Biological Molecules in Their Native State" (2006), Oxford University Press
  9. Frank J, "Three-dimensional reconstruction of the 70S Escherichia coli ribosome in ice: the distribution of ribosomal RNA", J. Cell Biol, 115, pp.597~605 (1991)
  10. Henderson R, "Three-dimensional model of purple membrane obtained by electron microscopy", Nature, 257, pp.28~ (1975)

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