스펙트럼영역 빛간섭단층촬영기로 측정한한국인 정상안의 황반부 용적
Mean Macular Volume in Normal Korean Eyes Measured by Spectral-domain Optical Coherence Tomography
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목적: 스펙트럼영역 빛간섭단층촬영기(SD-OCT)를 이용하여 한국인 정상안의 총 황반부 용적을 알아보고자 하였다. 대상과 방법: 안저검사상 정상이며, 교정시력 1.0 이상인 20세 이후의 한국인 132명 212안을 대상으로 SD-OCT를 이용하여 연령대별, 성별, 굴정이상의 정도 그리고 고혈압 혹은 당뇨 등의 전신질환 유무에 따라 총 황반부 용적을 비교 분석하였다. 결과: 전체 대상안의 평균 총 황반부 용적은 10.07±0.45 mm3였다. 청년군은 10.13±0.40 mm3, 장년군은 10.05±0.43 mm3, 노년군은 9.97±0.58 mm3로 측정되었고, 남성은 10.12±0.46 mm3, 여성은 9.97±0.40 mm3로 나타나 의미 있는 차이(p=0.028)를 보였다. 노년군에서 당뇨병 환자와 정상인은 의미 있는 차이(p=0.020)를 보였으며, 굴절이상에 따른 평균 황반부 용적의 차이는 의미가 없는 것으로 나타났다. 결론: 한국인 정상안의 평균 황반부 용적은 향후 황반부 병변의 진단과 경과관찰에 유용한 기준을 제공할 수 있을 것으로 기대된다.
Abstract
Purpose: To evaluate the mean macular volume in normal Korean eyes using spectral-domain optical coherence tomography. Methods: The present study consisted of 132 patients (212 eyes) with no ophthalmic evidence of retinopathy and who had a best corrected visual acuity of 1.0 or better. The total macular volume was measured using spectral-domain optical coherence tomography and was analyzed according to age group, sex, degree of refractive error and presence of systemic disease such as diabetes and hypertension. Results: The mean total macular volume of all subjects was 10.07±0.45 mm3, with means of 10.13±0.40 mm3, 10.05±0.43 mm3 and 9.97±0.58 mm3 measured for the respective A, B, and C age groups. There was a significant difference between male and female patients. In addition, there was a significant difference between diabetic patients in group C and normal subjects. However, there was no significant difference according to degree of refractive error. Conclusions: The measured value of mean macular volume in normal Korean eyes can be expected to provide a standard value for diagnosing retinal disease and the need for careful follow-up.
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