스펙트럼 영역 빛간섭단층촬영을 이용한 정시안과 근시안의 황반 형태 연구
A Study of Foveal Shape in Emmetropia and Myopia Using Spectral Domain Optical Coherence Tomography
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목적: 스펙트럼 영역 빛간섭단층촬영(SD-OCT)을 이용하여 20대 한국인의 정상 황반 형태에 대해 알아보고자 하였다. 대상과 방법: 20세에서 29세 사이의 정시안 60명 112안과 근시안 58명 100안을 대상으로 Spectralis OCT를 이용하여 중심황반두께,구역별 최대 망막두께, 오목직경, 오목 깊이, 기울기를 측정한 후 구면렌즈 대응치, 성별에 따른 차이를 분석하였다. 결과: 정시안과 근시안에서 이측 최대 망막두께는 다른 구역에 비해 얇았고(p<0.001) 오목직경은 두 군에서 모두 가로가 세로에 비해 유의하게 길었다(p<0.001). 근시안은 정시안보다 중심황반두께가 유의하게 두꺼웠으나 구역별 최대 망막두께는 유의하게 얇았고(p<0.001),오목직경과 오목 깊이도 유의하게 좁고 얕았다(p<0.001). 두 군에서 모두 남자가 여자보다 중심황반두께와 구역별 최대 망막두께가유의하게 두꺼웠으나(p<0.05) 가로 오목직경과 오목 깊이, 기울기는 성별에 따른 유의한 차이를 보이지 않았다. 결론: 정상안에서 황반의 형태는 구면렌즈 대응치, 성별에 따른 차이가 있어 해석에 주의를 요하며 정상 황반 형태를 파악함으로써추후 황반 연구에 좋은 기초자료가 될 수 있을 것이다.
Abstract
Purpose: To investigate the shape of normal fovea in Korean subjects in their 20’s using spectral domain optical coherence tomography(SD-OCT). Methods: One hundred-twelve emmetropic eyes of 60 subjects and 100 myopic eyes of 58 subjects between 20 and 29 years ofage were included in this study. Central foveal thickness (CFT), regional maximal retinal thickness (MRT), pit diameter, pit depth,and slope were obtained using Spectralis OCT and analyzed according to spherical equivalent and gender. Results: In emmetropic and myopic eyes, MRT was significantly thinner temporally (p < 0.001) than in other regions and pit diameterwas wider horizontally than vertically (p < 0.001). The CFT was significantly thicker and all regional MRT was thinner in myopiceyes than in emmetropic eyes (p < 0.001). Foveal pits were narrower and shallower in myopic eyes (p < 0.001). In bothgroups, CFT and all regional MRT in males were significantly thicker than in females (p < 0.05); however, no difference betweenthe genders in horizontal pit diameter, pit depth, and slope were found. Conclusions: In normal subjects, statistically significant differences were found in foveal shapes between subjects with differentspherical equivalent and gender. These differences should be considered when interpreting a foveal shape. Knowledge of thenormal foveal morphology is important when conducting further macular studies.
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