정상안압녹내장에서 초기 시야결손의 발생위치와 관련된 임상인자 분석
Analysis of Factors Related of Location of Initial Visual Field Defect in Normal Tension Glaucoma
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목적: 정상안압녹내장에서 초기 시야결손의 위치와 연관된 위험인자를 알아보고자 하였다. 대상과 방법: 정상안압녹내장으로 진단받은 환자 중 초기 녹내장성 시야결손을 보이는 81명을 중심시야 10도 이내에 암점이 존재하는경우 중심시야결손, 중심시야 10도 밖에 암점이 존재하는 경우 주변시야결손으로 분류한 후 성별, 나이, 고혈압, 당뇨, 흡연, 편측성,안압, 중심각막두께, 시신경유두함몰비, 시신경유두주위위축, mean deviation, pattern standard deviation, 최대교정시력, 굴절이상을비교분석하여 초기 시야결손의 위치와 연관된 위험인자를 분석하였다. 결과: 고혈압의 빈도가 중심시야결손군에서 60.6%로 주변시야결손군의 22.9%보다 더 높았고(p=0.001), 중심각막두께는 중심시야결손군에서 533.1 ± 18.2 μm로 주변시야결손군의 545.0 ± 30.0 μm보다 더 얇았다(p=0.003). 중심시야결손을 나타나게 하는 위험인자는 고혈압(p=0.001)만이 유의했고, 중심시야결손군 및 주변시야결손군 모두에서 하부보다 상부에서 더 많은 시야결손이 발생하였다. 결론: 정상안압녹내장에서 초기 중심시야결손에 관여하는 인자는 고혈압이었고, 시야결손은 주로 상부에 많았다.
Abstract
Purpose: To investigate the risk factors related to the location of visual field defects in normal tension glaucoma. Methods: Eighty-one eyes diagnosed as normal tension glaucoma in patients with early glaucomatous visual field defects were divided into central visual field defects and peripheral visual field defects. The difference between the 2 groups based on the intra-individual comparison were assessed with several ocular risk factors such as sex, age, hypertension, diabetes mellitus, smoking, laterality, intraocular pressure, central corneal thickness, cup-disc ratio, peripapillary atrophy, mean deviation,pattern standard deviation, best corrected visual acuity, and refractive errors. Results: The incidence of hypertension in the central visual field defects group (60.6%) was higher than in the peripheral visual field defects group (22.9%, p = 0.001). The central corneal thickness in the central group (533.1 ± 18.2 μm) was thinner than in the peripheral group (545.0 ± 30.0 μm, p = 0.003). Hypertension was the only risk factors for central visual field defects (p = 0.001). In both the central group and peripheral group, upper visual field defects were more common than lower defects. Conclusions: Hypertension in patients with normal tension glaucoma was a factor involved in central visual field defects. Additionally, numerous visual field defects were mainly found the superior portion.
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