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원발개방각녹내장, 정상안압녹내장 및 원발폐쇄각녹내장에서 시야진행의 비교 연구

Visual Field Progression in Patients with Primary Open Angle Glaucoma, Normal Tension Glaucoma, and Primary Angle Closure Glaucoma

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목적: 원발개방각녹내장, 정상안압녹내장 및 원발폐쇄각녹내장 환자에서 시야 진행의 패턴, 속도 및 위치에 대해 비교해보고자 하였다. 대상과 방법: 115안의 원발개방각녹내장, 123안의 정상안압녹내장, 92안의 원발폐쇄각녹내장 환자를 대상으로 후향적 의무기록 분석을 시행하였다. Mean deviation을 이용하여 전반적인 시야진행 속도를 분석하였고, 국소적인 시야진행은 암점확대와 암점심화로 나누어 각 군별로 상측활모양영역, 하측활모양영역, 중심부영역에서 분석하였다. 결과: 평균 전반적인 시야진행속도의 변화는 원발개방각녹내장군에서 -0.52 ± 0.74 dB/year, 정상안압녹내장군에서 -0.35 ± 0.41 dB/year, 원발폐쇄각녹내장군에서 -0.38 ± 0.45 dB/year로 원발개방각녹내장군에서 통계적으로 유의하게 빠른 진행 소견을 보였다(p<0.01). 원발개방각녹내장군은 상측활모양영역에서, 정상안압녹내장군은 중심부영역에서, 원발폐쇄각녹내장군은 하측활모양영역에서 큰 암점확대와 암점심화를 보였다. 결론: 원발개방각녹내장군에서는 상측활모양영역에서, 정상안압녹내장군에서는 중심부영역에서, 원발폐쇄각녹내장군에서는 하측활모양영역에서 큰 시야진행을 보였다.

Abstract

Purpose: We compared visual field progression among patients with primary open-angle glaucoma (POAG), normal tension glaucoma (NTG), and primary angle-closure glaucoma (PACG). Methods: A total of 115 POAG, 123 NTG, and 92 PACG eyes were retrospectively analyzed. Global VF progression was evaluated by calculating the changes of mean deviations. To examine local VF deterioration, scotoma enlargement and deepening were analyzed in the superior, and inferior arcuate, and the central, zones. Results: The mean global rate of change in POAG eyes was -0.52 ± 0.74 dB/year, and -0.35 ± 0.41, and -0.38 ± 0.45 dB/year in NTG and PACG eyes; POAG eyes showed significantly more rapid progression than NTG and PACG eyes (p < 0.01). The superior arcuate zone of POAG eyes, the central zone of NTG eyes, and the inferior arcuate zone of PACG eyes exhibited more scotoma enlargement and scotoma deepening than did other zones. Conclusions: The superior arcuate zone of POAG eyes, the central zone of NTG eyes, and the inferior arcuate zone of PACG eyes showed greater VF progression.

참고문헌 (42)

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