데스메막박리 각막내피층판이식술에서 공여자 각막내피절편 두께에 따른 시력 예후
The Correlations between Donor Endothelial Lenticule Thickness and Visual Prognosis in DSAEK
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목적: 데스메막박리 각막내피층판이식술(Descemet stripping automated endothelial keratoplasty, DSAEK)에서 공여자 각막내피절편두께가 얇을수록 술 후 시력 예후가 좋을 것인지 알아보고자 한다. 대상과 방법: 2008년 1월부터 2010년 12월까지 본원에서 각막내피부전증으로 DSAEK 수술을 받은 22명 22안을 대상으로 공여자 각막내피절편 두께 130 μm를 기준으로 이보다 얇은 경우 thin lenticule 군으로, 두꺼운 경우 thick lenticule 군으로 나누어 각각 1, 3, 6개월에서의 시력(logMAR)을 비교하였다. 결과: Thin lenticule과 thick lenticule 군에서의 술 후 1개월 최대교정시력(logMAR)은 각각 0.46 ± 0.22, 0.71 ± 0.26 (p=0.025),3개월 최대교정시력(logMAR)은 각각 0.36 ± 0.17, 0.54 ± 0.32 (p=0.129), 6개월 최대교정시력(logMAR)은 0.27 ± 0.15, 0.38 ± 0.18(p=0.141)이었다. 결론: DSAEK 수술에서 공여자 각막내피절편 두께가 130 μm 보다 얇은 경우 술 후 1개월째만 내피의 두께가 130 μm 이상인 경우보다좋아 공여자 각막내피절편 두께는 술 후 1개월 후의 단기 시력 예후에만 영향을 미치는 것을 알 수 있었다.
Abstract
Purpose: To determine the correlations between donor endothelial lenticule thickness and visual prognosis in Descemet’s stripping automated endothelial keratoplasty (DSAEK). Methods: The present study included 22 patients (22 eyes), who underwent DSAEK surgery in our clinic due to endothelial decompensation. BCVA (log MAR) was compared at 1 month, 3 months and 6 months postoperatively between the thin lenticule group and thick lenticule group (≥130 μm). Results: The BCVA (log MAR) at 1 month postoperatively was 0.46 ± 0.22 in the thin lenticule group, and 0.71 ± 0.26 in the thick lenticule group, and significant statistical correlations between donor lenticule thickness and visual acuity were observed (p = 0.025). However, no significant correlations were observed at 3 months (p = 0.129) and 6 months (p = 0.141)postoperatively. Conclusions: The thin donor lenticule (<130 μm) can result in better visual acuity at 1 month postoperatively than the thick donor lenticule (≥130 μm), however, there is no difference in visual acuity between the 2 groups at 3 and 6 months postoperatively.
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