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휴대용 안압계와 골드만 압평안압계로 측정한 안압 비교

Comparison of Portable Tonometers and Goldmann Applanation Tonometer for Intraocular Pressure Measurement

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초록

목적: 휴대용 안압계인 rebound 안압계와 TonoPen 압평안압계로 측정한 안압을 Goldmann 압평안압계(GAT)로 측정한 안압과 비교하고, 이에 영향을 줄 수 있는 인자들을 알아보고자 하였다. 대상과 방법: 463안을 대상으로 Icare ProⓇ rebound 안압계, TonoPen AVIAⓇ 압평안압계, 그리고 GAT로 안압을 측정하였다. 각 안압계로 측정한 안압의 일치도와 이에 영향을 미칠 수 있는 인자를 분석하기 위해 Bland-Altman plot, 급내상관계수, Pearson 상관분석및 다중회귀분석을 시행하였다. 결과: Icare ProⓇ 안압과 TonoPen AVIAⓇ 안압은 각각 GAT 안압보다 높게 측정되었지만 유의한 차이는 보이지 않았으며(p=0.307,p=0.114), Bland-Altman plot에서 GAT 안압과 높은 일치도를 보였다. Icare ProⓇ 안압과 GAT 안압, 그리고 Tonopen AVIAⓇ 안압과GAT 안압의 차이는 중심각막두께가 증가할수록(p=0.019, p=0.035) 또는 연령이 감소할수록(p=0.041, p=0.049), 각각 증가하였다. 결론: 휴대용 안압계인 Icare ProⓇ rebound 안압계와 TonoPen AVIAⓇ 압평안압계로 측정한 안압은 GAT로 측정한 안압과 뚜렷한상관관계를 보여, GAT로 측정이 어려운 환자에서 유용하게 사용될 수 있을 것으로 생각되나, 안압 측정 시 중심각막두께와 연령 등을고려하여야 하겠다.

Abstract

Purpose: To compare the intraocular pressure (IOP) measured by portable rebound tonometer and TonoPen applanationtonometer with pressure measured by Goldmann applanation tonometer (GAT) and analyze the factors affecting IOP disagreementbetween tonometers. Methods: In a prospective study of 463 eyes, IOP was measured with Icare Pro® rebound tonometer, TonoPen AVIA® applanationtonometer, and GAT. Bland-Altman plot, intraclass correlation coefficient, Pearson’s correlation analysis, andmultiple regression analysis were performed to evaluate the agreement of IOP measured by each tonometer and the factorsaffecting the measurements. Results: The IOP values measured by Icare Pro® and TonoPen AVIA® were consistently higher than those measured byGAT, but showed no significant differences with those measured by GAT (p = 0.307 and 0.114, respectively). In Bland-Altman plot, the IOP values measured by Icare Pro® and TonoPen AVIA® exhibited excellent agreement with those measuredby GAT. Both Icare Pro®/GAT and TonoPen AVIA®/GAT differences increased with younger age (p = 0.041 and0.049, respectively) and higher central corneal thickness (p = 0.019 and 0.035, respectively). Conclusions: IOPs measured by portable Icare Pro® rebound tonometer and TonoPen AVIA® applanation tonometer weresignificantly correlated with IOP measured by GAT. Therefore, such instruments can be useful when measuring IOP withGAT is difficult. However, central corneal thickness and age should be considered when measuring IOP with portabletonometers.

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