한국인 눈꺼풀 악성종양의 임상 양상
Clinicopathological Characteristics of Malignant Eyelid Tumor in Korea
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목적: 우리나라 눈꺼풀 악성종양 환자의 임상 양상과 결과를 알아보고자 한다. 대상과 방법: 2004년 4월부터 2012년 9월까지 눈꺼풀 악성종양으로 조직학적 진단을 받고 최소 6개월 이상 추적관찰 가능한 73명의의무기록을 후향적으로 조사하였다. 결과: 총 73명의 환자가 눈꺼풀 악성종양으로 진단 받았으며, 진단 당시 나이는 68.4 ± 11.5세였다. 종양은 아래눈꺼풀에 더 호발하는경향을 보였다(40명, 54.8%). 종양을 조직학적으로 분류하면 바닥세포암 41명(56.2%), 편평세포암 17명(23.3%), 피지샘암 11명(15.1%),악성흑색종 3명(4.1%), 바닥편평세포암 1명(1.4%)이었다. 대부분의 환자들이 조직학적 진단 시행 후 종양의 완전 절제 및 눈꺼풀 재건술(95.9%)을 시행하였다. 바닥세포암과 편평세포암은 피지샘암, 악성흑색 종과 비교해 상대적으로 낮은 재발률을 나타내어 더 좋은예후를 보였다. 결론: 눈꺼풀 악성종양으로 진단된 73명의 환자 중 가장 흔한 종양은 바닥세포암(56.2%)이었으며, 대부분의 종양은 완전 절제술 및재건술 이후 재발 소견은 흔하지 않았다.
Abstract
Purpose: To determine the clinical characteristics of patients with malignant eyelid tumors in Korea. Methods: We performed a retrospective review of the medical records of 73 patients with malignant eyelid tumors whowere histologically diagnosed at Seoul St. Mary’s hospital from April 2004 to September, 2012 and followed for 6 monthsor longer. Results: Of 73 cases, 41 (56.2%) were diagnosed as basal cell carcinoma, 17 (23.3%) as squamous cell carcinoma, 11(15.1%) as sebaceous gland carcinoma, 3 (4.1%) as malignant melanoma, and 1 (1.4%) as basosquamous cell carcinoma. The mean age at diagnosis was 68.4 ± 11.5 years. Tumors developed more commonly on the lower lid (54.8%). Most caseswere treated by complete resection of tumors and eyelid reconstruction (95.9%). The prognosis of patients with basal cellcarcinoma and squamous cell carcinoma was good, while that of the other tumors was relatively poor. Conclusions: The most common diagnosis was basal cell carcinoma (56.2%). Recurrence after complete surgical excisionand reconstruction was uncommon.
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