눈꺼풀 양성종양의 임상 양상
Clinical Characteristics of Benign Eyelid Tumors
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목적: 눈꺼풀에서 발생한 양성종양의 임상 양상과 발생 빈도에 대해 알아보고자 하였다. 대상과 방법: 2009년 1월부터 2014년 12월까지 고려대학교 안산병원 안과에서 조직학적으로 진단 받은 192명의 눈꺼풀 양성종양 환자의 의무기록을 후향적으로 조사하였다. 결과: 총 192명의 환자가 눈꺼풀 양성종양으로 진단 받았으며, 남자 87명(45.3%), 여자 105명(54.7%)이었다. 진단 당시 환자들의 평균연령은 42.6 ± 19.2세로 40대가 가장 많았고, 지루성 각화증(60.2 ± 15.8세), 편평 상피 유두종(50.5 ± 13.4세)은 평균 연령이 더 높았으며, 물사마귀(5.5 ± 3.5세), 모기질종(14.0 ± 15.6세)은 더 낮았다. 발생 위치는 위눈꺼풀이 아래 눈꺼풀보다 더 많았다(121안, 63.0%). 조직학적으로 분류해 보면 멜라닌 세포성 모반(72명, 37.5%), 표피낭종(16명, 8.3%), 편평 상피 유두종(11명, 5.7%), 지루성각화증(10명, 5.2%) 순이었다. 결론: 눈꺼풀 양성종양으로 진단된 192명의 환자 중 가장 흔한 것은 멜라닌 세포성 모반이었다. 본 연구가 임상에서 눈꺼풀 종양에 대한 역학적 정보를 제공하고 진단과 치료에 도움이 될 수 있을 것으로 생각한다.
Abstract
Purpose: To report the relative frequency and clinical characteristics of patients with benign eyelid tumors. Methods: A retrospective study of 192 consecutive patients admitted to Korea University Ansan Hospital with benign eyelid tumor between January 2009 and December 2014 was undertaken, and clinical records including age, sex, involved site, and pathology of tumors were reviewed retrospectively. All eyelid tumors were confirmed histopathologically. Results: The sexual distribution revealed 87 males and 105 females with benign eyelid tumors. The mean age at diagnosis was 42.6 ± 19.2 years. Molluscum contagiosum (5.5 ± 3.5 years) and pilomatrixoma (14.0 ± 15.6 years) were generally found in younger individuals, while seborrheic keratosis (60.2 ± 15.8 years) and squamous cell papilloma (50.5 ± 13.4 years) occurred predominantly in elderly patients. Tumors were most common on the upper lid (63.0%). The four most frequent subtypes were melanocytic nevus (37.5%), epidermal cyst (8.3%), squamous cell papilloma (5.7%), and seborrheic keratosis (5.2%). Conclusions: The most common histopathological diagnosis of benign eyelid tumors was melanocytic nevus. The results of this study provide epidemiological information that will be useful for diagnosis and therapy of such tumors.
참고문헌 (21)
- Welch RB., "Lesions of the lids;a statistical note", Am J Ophthalmol, 45, pp.415~426 (1958)
- Allington HV., "Eyelid tumors", Arch Dermatol, 97, pp.50~65 (1968)
- Lee HK., "Clinical analysis of lid tumors", J Korean Ophthalmol Soc, 38, pp.1892~1898 (1997)
- Deprez M., "Clinicopathological features of eyelid skin tumors. A retrospective study of 5504 cases and review of literature", Am J Dermatopathol, 31, pp.256~262 (2009)
- Hornblass A., "Oculoplastic, Orbital and Reconstructive Surgery. Vol. 1", pp.193~205 (1988), Williams & Wilkins
- O’Brien CS., "Common tumors of the eyelids", J Am Med Assoc, 107, pp.933~938 (1936)
- Reese AB., "Tumors of the Eye", pp.54~56 (1976), Harper & Row
- Bak SI., "Benign tumors of the eye and its adnexa", J Korean Ophthalmol Soc, 19, pp.333~339 (1978)
- Lee TS., "Analysis of classification and incidence of eyelid and orbital tumors", J Korean Ophthalmol Soc, 38, pp.1700~1705 (1997)
- 최준호, "양성 안검 및 결막종양의 임상적 고찰", 대한안과학회지, 44(6), pp.5~1277 (2003), 대한안과학회
- Al-Faky YH, "Epidemiology of benign eyelid lesions in patients presenting to a teaching hospital", Saudi J Ophthalmol, 26, pp.211~216 (2012)
- Lee JC., "Clinical and histopathological observation on acquired melanocytic nevus(1975~1985)", Korean J Dermatol, 26, pp.874~878 (1988)
- Older JJ., "Eyelid Tumors. Clinical Diagnosis and Surgical Treatment", pp.47~ (2003), Raven Press
- Lee GS., "A histopathologic study of the seborrheic keratosis", Korean J Dermatol, 30, pp.76~80 (1992)
- Choi YH., "A stastistical survey of cutaneous epithelial cysts", Korean J Dermatol, 24, pp.61~66 (1986)
- Orlando RG., "Pilomatricoma in a pediatric hospital", Arch Ophthalmol, 101, pp.1209~1210 (1983)
- Perez RC., "Malherbe’s calcifying epithelioma (pilomatrixoma) of the eyelid. Clinical features", Arch Ophthalmol, 97, pp.314~315 (1979)
- Smith RJ., "Multiple apocrine hidrocystomas of the eyelids", Orbit, 31, pp.140~142 (2012)
- Moehlenbech FW, "Pilomatrixoma(calcifying epithelioma)", Arch Dermatol, 108, pp.532~534 (1973)
- Kim KH., "Classification and therapeutic effect of benign and malignant eyelid tumors", J Korean Ophthalmol Soc, 38, pp.703~709 (1997)
- Kersten RC., "Accuracy of clinical diagnosis of cutaneous eyelid lesions", Ophthalmology, 104, pp.479~484 (1997)