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Orbital Sarcoidosis Presenting as Diffuse Swelling of the Lower Eyelid

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초록

The author reports a case of orbital Sarcoidosis in a 70-year-old female that initially presented as diffuse swelling of the lower eyelid. The patient complained of painless swelling of the left lower lid without palpable mass, and a computerized tomography (CT) scan of the orbit was unremarkable. A serum angiotensin converting enzyme level was elevated, and hilar lymphadenopathy was noted on the chest CT. The patient underwent surgical debulking for histologic confirmation, which led to a final diagnosis of sarcoidosis involving the orbital fat. Unexplained chronic eyelid swelling without a mass should be considered a possible ophthalmic manifestation of orbital sarcoidosis.

Abstract

The author reports a case of orbital Sarcoidosis in a 70-year-old female that initially presented as diffuse swelling of the lower eyelid. The patient complained of painless swelling of the left lower lid without palpable mass, and a computerized tomography (CT) scan of the orbit was unremarkable. A serum angiotensin converting enzyme level was elevated, and hilar lymphadenopathy was noted on the chest CT. The patient underwent surgical debulking for histologic confirmation, which led to a final diagnosis of sarcoidosis involving the orbital fat. Unexplained chronic eyelid swelling without a mass should be considered a possible ophthalmic manifestation of orbital sarcoidosis.

참고문헌 (8)

  1. Prabhakaran VC, "Orbital and adnexal sarcoidosis", Arch Ophthalmol, 125, pp.1657~1662 (2007)
  2. Simon EM, "Systemic sarcoidosis with bilateral orbital involvement: MR findings", AJNR Am J Neuroradiol, 19, pp.336~337 (1998)
  3. Biswas J, "Lid swelling and diplopia as presenting features of orbital sarcoid", Indian J Ophthalmol, 48, pp.231~233 (2000)
  4. Pollock JM, "Neurosarcoidosis mimicking a malignant optic glioma", J Neuroophthalmol, 28, pp.214~216 (2008)
  5. Mavrikakis I, "Diverse clinical presentations of orbital sarcoid", Am J Ophthalmol, 144, pp.769~775 (2007)
  6. Moin M, "Destructive eyelid lesions in sarcoidosis", Ophthal Plast Reconstr Surg, 17, pp.123~125 (2001)
  7. Marchell RM, "Cutaneous sarcoidosis", Semin Respir Crit Care Med, 31, pp.442~451 (2010)
  8. Shaikh ZA, "Orbital involvement as the initial manifestation of sarcoidosis: magnetic resonance imaging findings", J Neuroimaging, 10, pp.180~183 (2000)

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