뇌혈관 전산화단층촬영을 이용한 한국인의 연령대별정상 눈물샘 용적의 측정
Calculated Brain CT Angiography Volumes of Lacrimal Glands in Normal Korean Orbits
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목적: 뇌혈관 전산화단층촬영을 이용하여 한국인의 연령대별 눈물샘 용적을 측정하여 정상 범위를 확인하고자 한다. 대상과 방법: 안질환 및 안수술의 기왕력이 없는 정상 성인 107명 214안을 대상으로 20대부터 70대까지 뇌혈관 전산화단층촬영을시행한 환자들의 눈물샘 용적을 후향적으로 측정하였다. Aquaris Intuition Viewer software를 이용하여 눈물샘의 용적을 계산하였다. 결과: 평균 눈물샘 용적은 우안 0.655 cm3 (SD=0.15), 좌안 0.595 cm3 (SD=0.16)로 우안과 좌안의 눈물샘 용적은 유의한 차이가있었다(p=0.012). 남자와 여자의 평균 눈물샘 용적은 남자 0.616 cm3 (SD =0.17), 여자 0.625 cm3 (SD=0.15)로 유의한 차이(p=0.627)가 없었다. 눈물샘의 평균 용적과 나이는 음의 상관 관계(Pearson r=-0.433, p＜0.001)를 보였다. 결론: 본 연구는 한국인의 눈물샘 용적의 정상 범위를 뇌혈관 전산화단층촬영을 이용하여 측정하였다는 것에 의미가 있다. 눈물샘용적은 나이가 증가할수록 감소하며 남녀의 차이는 없었다. 서양인의 보고와 비교하여 한국인에서 눈물샘의 용적이 작았으며 좌우눈물샘 용적은 유의한 차이를 보였다. 한국인의 정상 눈물샘 용적의 측정치를 이용하여 병적인 눈물샘의 상태를 진단하는 데 도움이될 것으로 생각한다.
Abstract
Purpose: To determine the size range of lacrimal glands calculated from Brain CT angiography. Methods: A retrospective review of 107 CT scans of 214 orbits was performed. Aquaris Intuition Viewer software was used tocalculate the volumes. Results: The mean volume of the lacrimal gland was 0.655 cm3 in right orbits and 0.595 cm3 in left orbits, 0.616 cm3 in men and0.625 cm3 in women. There was a significant difference between right and left (p = 0.012) but no difference between men andwomen (p = 0.725). Linear regression analyses revealed that there was an inverse relationship between gland volume and age(Pearson r = -0.433, p < 0.001). Conclusions: This is the first study to report the normal volume range of Korean lacrimal glands as measured by CT scans. A differencewas detected in the volume between right and left lacrimal glands. The volume of the lacrimal gland decreased with age,and there were no gender differences.
참고문헌 (18)
- Lorber M, "Gross characteristics of normal human lacrimal glands", Ocul Surf, 5, pp.13~22 (2007)
- Bron AJ, "Lacrimal streams: the demonstration of human lacrimal fluid secretion and the lacrimal ductules", Br J Ophthalmol, 70, pp.241~245 (1986)
- Hughes GK, "Imaging of the lacrimal gland", Semin Ultrasound CT MR, 27, pp.476~491 (2006)
- 정원상, "The Radiological Spectrum of Orbital Pathologies that Involve the Lacrimal Gland and the Lacrimal Fossa", Korean Journal of Radiology, 8(4), pp.336~342 (2007), 대한영상의학회
- Tamboli DA, "Computed tomography dimensions of the lacrimal gland in normal Caucasian orbits", Ophthal Plast Reconstr Surg, 27, pp.453~456 (2011)
- Ueno H, "MR imaging of the lacrimal gland. Age-related and gender-dependent changes in size and structure", Acta Radiol, 37, pp.714~719 (1996)
- Lee JS, "Computed tomographic dimensions of the lacrimal gland in healthy orbits", J Craniofac Surg, 24, pp.712~715 (2013)
- Avetisov SE, "Ultrasound spatial clinical analysis of the orbital part of the lacrimal gland in health", Vestn Oftalmol, 122, pp.14~16 (2006)
- Lorber M, "Gross characteristics of normal human lacrimal glands", Ocul Surf, 5, pp.13~22 (2007)
- Barrett JF, "Artifacts in CT: recognition and avoidance", Radiographics, 24, pp.1679~1691 (2004)
- Landis JR, "The measurement of observer agreement for categorical data", Biometrics, 33, pp.159~174 (1977)
- Rootman J, "Diseases of the orbit: a multidisciplinary approach", pp.344~ (2003), Lippincott Williams and Wilkins
- Harris MA, "CT dimensions of the lacrimal gland in Graves orbitopathy", Ophthal Plast Reconstr Surg, 28, pp.69~72 (2012)
- Forbes G, "Volume measurements of normal orbital structures by computed tomographic analysis", AJR Am J Roentgenol, 145, pp.149~154 (1985)
- Bingham CM, "Calculated CT volumes of lacrimal glands in normal Caucasian orbits", Ophthal Plast Reconstr Surg, 29, pp.157~159 (2013)
- Lorber M, "Measurements of lacrimal glands from cadavers, with descriptions of typical glands and three gross variants", Orbit, 28, pp.137~146 (2009)
- Obata H, "Anatomy and histopathology of the human lacrimal gland", Cornea, 25, pp.S82~S89 (2006)
- Obata H, "Statistical analysis with special reference to aging", Ophthalmology, 102, pp.678~686 (1995)