전산화 단층촬영으로 측정한 정상 한국인의 눈물샘 부피
Calculated CT Volumes of Lacrimal Glands in Normal Korean Orbits
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목적: 전산화 단층촬영을 이용하여 정상 한국인의 눈물샘의 부피 및 연령에 따른 크기 변화를 알아보고자 하였다. 대상과 방법: 2013년 1월부터 2013년 8월까지 본원에서 안면골 전산화 단층촬영 및 안와 전산화 단층촬영을 시행한 환자 중 눈물샘및 안와에 특이 질환이 없는 111명 213안을 후향적으로 조사하였다. 연속적인 축방향 전산화 단층촬영 이미지에서 Aquaris intuition(Tera Recon, Foster city, CA, USA)의 pencil tool technique을 이용하여 눈물샘의 부피를 측정하였고, 눈물샘 부피의 분포 및 연령에 따른 눈물샘의 부피변화를 분석하였다. 결과: 눈물샘의 평균 부피는 우안 0.589 cm3 (SD=0.090), 좌안 0.583 cm3 (SD=0.089), 남성 0.596 cm3 (SD=0.083), 여성 0.575 cm3(SD=0.094)로 좌, 우안(p=0.614) 및 성별에(p=0.102) 따른 유의한 차이는 보이지 않았다(2-sample t-test). 실험군 전체를 대상으로하여 연령대별 눈물샘의 부피를 살펴보면 20-40세 0.630 cm3 (SD=0.080), 41-60세 0.553 cm3 (SD=0.734), 61세 이상 0.544 cm3(SD=0.885)로 연령이 증가할수록 눈물샘의 부피는 감소하였다(Pearson r=-0.384, p=0.00). 결론: 눈물샘의 부피는 좌, 우안 및 성별에 따른 차이는 없었고, 연령이 증가할수록 눈물샘의 부피가 감소하였다.
Abstract
Purpose: We used computed tomography (CT) scans to describe normal Korean lacrimal gland volume and lacrimal gland sizeand then examined their correlations with patient age. Methods: CT scans were obtained in 213 orbits of 111 patients who underwent CT from January to August of 2013. AquariusiNtuition (TeraRecon, Foster City, CA, USA) software was used to outline the lacrimal gland in consecutive axial slices and tocalculate the volume. Results: The mean volume of the lacrimal gland was 0.589 cm3 in right orbits (SD = 0.090), 0.583 cm3 in left orbits (SD = 0.289),0.596 cm3 in males (SD = 0.083), and 0.575 cm3 in females (SD = 0.094). There was no significant difference in mean lacrimalgland volume according to laterality (p = 0.614) or sex (p = 0.102) (2-sample t-tests). We investigated mean lacrimal gland volumein 3 age groups. Mean lacrimal gland volume was 0.630 cm3 (SD = 0.080) for the 20 to 40 year old group, 0.553 cm3 (SD =0.734) for the 41 to 60 year old group, and 0.544 cm3 (SD = 0.885) for the older than 60 years old group. There was an inverserelationship between gland volume and age (Pearson r = −0.384, p = 0.00). Conclusions: The mean volume of the lacrimal gland decreased with age and there was no significant difference between rightand left orbits or between male and female patients.
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