녹내장 환자의 약물 순응도 조사
Assessment of Glaucoma Medication Compliance
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목적: 녹내장 환자의 약물 치료 순응도와 영향요인을 알아보고자 한다. 대상과 방법: 녹내장으로 안약 점안 중인 415명의 환자를 대상으로 약물 순응도 및 부작용에 대한 설문조사를 시행하였다. 약물 순응도는 한 달 기준으로 약물을 용법대로 제대로 점안하지 못하는 날의 일수를 이용하여 순응도 점수(범위, 0–100)를 산출하였고, 녹내장및 약물 관련 증상과 부작용은 Glaucoma Symptom Scale (GSS)을 이용하여 평가하였다. 환자의 성별, 나이, 치료 기간, 약물 용법에대한 지식, 약물 개수, 약물의 종류, 약물 점안하는 사람(본인 또는 가족), GSS에 따라 녹내장 약물 순응도에 차이가 있는지 분석하였다. 결과: 안약을 용법대로 제대로 점안하지 않은 날은 한 달 중 하루에서 나흘이 가장 많았다(43.4%). 그 이유는 ‘깜빡 잊어버려서(80.5%)’, ‘바빠서(18.4%)’, ‘부작용 때문에(1.1%)’ 순이었다. 순응도 점수는 10.0부터 100.0까지의 분포를 보였고 중위값은 90.0이었다. 나이가 많을수록, 치료기간이 길수록, 약물 용법에 대한 지식이 높을수록, 가족이 안약을 점안해주는 경우에 높은 녹내장 약물 순응도를 보였다(p＜0.05). 성별, 약물의 종류나 개수, 약물관련 부작용은 약물 순응도에 유의한 영향을 주지 않았다. 결론: 나이, 치료기간, 약물 용법에 대한 이해, 가족의 안약 점안 도움이 녹내장 약물 치료 순응도에 영향을 주는 것으로 나타났다. 녹내장 환자의 약물 순응도를 높이기 위해 이 요인들을 고려하는 것이 치료에 도움이 될 것으로 생각한다.
Abstract
Purpose: To assess glaucoma medication compliance and its causative factors in glaucoma patients. Methods: This study was performed via a structured questionnaire given to 415 glaucoma patients using eye drops for glaucomatreatment. The degree of compliance was evaluated by using compliance score (range, 0–100) which was calculated based onthe number of days of missing medication per month. The degree of symptoms and complications related to glaucoma and itsmedication were investigated using the Glaucoma Symptom Scale (GSS). The effect of sex, age, treatment duration, knowledgeabout the glaucoma medication, number of eye drops, class of glaucoma medication, family support for eye drop use, and GSSon glaucoma medication compliance was assessed. Results: The most frequently found number of days of missing medication per month was one to four (43.4%). The most commonreason for missing medication was forgetfulness (80.5%), followed by busy daily schedule (18.4%) and complications of medication(1.1%). Compliance score ranged from 10.0 to 100.0 (median value, 90.0). Older age, longer duration of treatment, higherknowledge about the glaucoma medication, and the presence of family support was significantly associated with a higher compliancescore (p < 0.05). Sex, number and class of eye drops, and GSS did not significantly affect compliance score. Conclusions: Age, treatment duration, knowledge about the glaucoma medication, and familial support were affecting factors forglaucoma medication compliance. To enhance glaucoma medication compliance, these factors should be considered.
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