The Effect of Pattern Scan Laser Photocoagulation on Peripapillary Retinal Nerve Fiber Layer Thickness and Optic Nerve Morphology in Diabetic Retinopathy
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Primary open anglPurpose: To evaluate the effect of pattern scan laser (PASCAL) photocoagulation on peripapillary retinal nervefiber layer (RNFL) thickness, central macular thickness (CMT), and optic nerve morphology in patients withdiabetic retinopathy. Methods: Subjects included 35 eyes for the PASCAL group and 49 eyes for a control group. Peripapillary RNFLthickness, cup-disc area ratio and CMT were measured before PASCAL photocoagulation and at 2 and 6months after PASCAL photocoagulation in the PASCAL or control groups. Results: The average RNFL thickness had increased by 0.84 μm two months after and decreased by 0.4 μmsix months after PASCAL photocoagulation compared to baseline, but these changes were not significant (p =0.83, 0.39). The cup-disc area ratio was unchanged after PASCAL photocoagulation. CMT increased by 18.11μm (p = 0.048) at two months compared to baseline thickness, and partially recovered to 11.82 μm (p = 0.11)at six months in the PASCAL group. Conclusions: PASCAL photocoagulation may not cause significant change in the peripapillary RNFL thickness,CMT, and optic nerve morphology in patients with diabetic retinopathy.e glaucoma, Prostaglandins, Timolol
Abstract
Purpose: To evaluate the effect of pattern scan laser (PASCAL) photocoagulation on peripapillary retinal nervefiber layer (RNFL) thickness, central macular thickness (CMT), and optic nerve morphology in patients withdiabetic retinopathy. Methods: Subjects included 35 eyes for the PASCAL group and 49 eyes for a control group. Peripapillary RNFLthickness, cup-disc area ratio and CMT were measured before PASCAL photocoagulation and at 2 and 6months after PASCAL photocoagulation in the PASCAL or control groups. Results: The average RNFL thickness had increased by 0.84 μm two months after and decreased by 0.4 μmsix months after PASCAL photocoagulation compared to baseline, but these changes were not significant (p =0.83, 0.39). The cup-disc area ratio was unchanged after PASCAL photocoagulation. CMT increased by 18.11μm (p = 0.048) at two months compared to baseline thickness, and partially recovered to 11.82 μm (p = 0.11)at six months in the PASCAL group. Conclusions: PASCAL photocoagulation may not cause significant change in the peripapillary RNFL thickness,CMT, and optic nerve morphology in patients with diabetic retinopathy.
참고문헌 (19)
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