Simplified Correction of Ischemic Index in Diabetic Retinopathy Evaluated by Ultra-widefield Fluorescein Angiography
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Purpose: To develop a novel, simplified method for correcting the ischemic index of nonperfused areas in diabeticretinopathy (DR). Methods: We performed a retrospective review of 103 eyes with naive DR that underwent ultra-widefield angiography(UWFA) over a year. UWFAs were graded according to the quantity of retinal non-perfusion, anduncorrected ischemic index (UII) and corrected ischemic index (CII) were calculated using a simplified, novelmethod. Results: The average differences between UII and CII in the non-proliferative DR group and the proliferative DRgroup were 0.7 ± 0.9% in the <25% CII group, 3.0 ± 0.9% in the 25% to 49.9% CII group, and 3.6 ± 0.6% in the>50% CII group, respectively. A CII >25% was critical for determining DR progression (p < 0.001). Conclusions: Distortion created by UWFA needs to be corrected because the difference between UII and CII inDR increases with the ischemic index.
Abstract
Purpose: To develop a novel, simplified method for correcting the ischemic index of nonperfused areas in diabeticretinopathy (DR). Methods: We performed a retrospective review of 103 eyes with naive DR that underwent ultra-widefield angiography(UWFA) over a year. UWFAs were graded according to the quantity of retinal non-perfusion, anduncorrected ischemic index (UII) and corrected ischemic index (CII) were calculated using a simplified, novelmethod. Results: The average differences between UII and CII in the non-proliferative DR group and the proliferative DRgroup were 0.7 ± 0.9% in the <25% CII group, 3.0 ± 0.9% in the 25% to 49.9% CII group, and 3.6 ± 0.6% in the>50% CII group, respectively. A CII >25% was critical for determining DR progression (p < 0.001). Conclusions: Distortion created by UWFA needs to be corrected because the difference between UII and CII inDR increases with the ischemic index.
참고문헌 (9)
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